Articoli correlati a Proteases in Gastrointestinal Tissues: 5
This book is unique for its comprehensive presentation of protease function in the stomach, colon, pancreas and liver under both physiological conditions and major diseases manifesting in these four organs. The individual chapters have been written by leaders in the field who outline in great detail the role of proteases in the pathogenesis, diagnosis and treatment of disease. Animal models and experimental data are discussed in the context of patient-derived data.
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Contenuti:
Contributing Authors Preface Chapter 1 Protease-Activated Receptors in Gastrointestinal Function and Disease Nigel W. Bunnett and Graeme S. Cottrell Chapter 2 Matrix Metalloproteinases in Gastric Cancer Nikhil I. Khushalani and Nithya Ramnath Chapter 3 Proteases in Helicobacter pylori-Mediated Diseases Thomas Wex, Michael Zack, and Peter Malfertheiner Chapter 4 Proteases in Pancreatic Disease Avinash Sewpaul, Jeremy J. French, and Richard M. Charnley Chapter 5 PAR in the Pathogenesis of Pain in Pancreatic Disease Pankaj J. Pasricha Chapter 6 Importance of the Local Renin-Angiotensin System in Pancreatic Disease Po Sing Leung Chapter 7 Hepatitis C Viral Proteases And Inhibitors Mingjun Huang, Avinash Phadke and Atul Agarwal Chapter 8 Angiotensin Converting Enzyme in the Pathophysiology of Liver Fibrosis Yao Hong Wie Chapter 9 Matrix Metalloproteinases in Chronic Liver Disease and Liver Transplantation Hein W. Verspaget, Johan P. Kuyvenhoven, Cornelis F. M. Sier, Bart van Hoek Chapter 10 MMPs and ADAMs in Inflammatory Bowel Disease Alicja Wiercinska-Drapalo, Jerzy Jaroszewicz, Anna Parfieniuk, Anna Moniuszko Chapter 11 Chemokines and Matrix Metalloproteinases in Colorectal Cancer Gayle G. Vaday and Stanley Zucker Chapter 12 Angiotensin-Converting Enzyme (ACE) in Gut Inflammation Fernando Magro Chapter 13 Intestinal Apical Protein Transport in Health and Disease Stephan von Hörsten, Michael Krahn, Nadine Frerker, Anja Gemeinhardt, Dennis Schwab, Silvia Slesiona, Hassan Naim, and Marwan Alfalah Index
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- EditoreSpringer
- Data di pubblicazione2010
- ISBN 10 9048171342
- ISBN 13 9789048171347
- RilegaturaCopertina flessibile
- Numero di pagine364
- RedattoreLendeckel Uwe, Hooper Nigel M.
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Proteases in Gastrointestinal Tissues (Proteases in Biology and Disease) [Paperback ]
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Proteases in Gastrointestinal Tissues (Proteases in Biology and Disease, 5)
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Descrizione libro Condizione: New. Codice articolo ABLIING23Apr0316110338347
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Proteases in Gastrointestinal Tissues
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Descrizione libro Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is unique for its comprehensive presentation of protease function in the stomach, colon, pancreas and liver under both physiological conditions and major diseases manifesting in these four organs. The individual chapters have been written by leaders in the field who outline in great detail the role of proteases in the pathogenesis, diagnosis and treatment of disease. Animal models and experimental data are discussed in the context of patient-derived data. 364 pp. Englisch. Codice articolo 9789048171347
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Proteases in Gastrointestinal Tissues
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Descrizione libro Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Devoted to proteases in liver, stomach, colon, pancreas specifically and extensivelyCovers major diseases of gastrointestinal tissuesIntroducing individual proteases (or families of) extensivelyUp to date presentation of patient-deri. Codice articolo 5820978
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Descrizione libro Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This, the fifth volume in the Proteases in Biology and Disease series, is devoted to Proteases in Gastrointestinal Tissues. Of course, proteases play an important role in the digestion and utilization of ingested proteins, but besides that they elicit a wide range of physiological and pathological effects. Proteases have been recognized as essential regulators, acting both locally and systemically, of normal development, growth and functioning. Dysregulation of protease expression and/or enzymatic activity is often associated with the onset or progression of disease and, thus, proteases represent interesting targets for the pharmacological therapy of e. g. cancer, chronic inflammation, graft rejection, fibrosis, diabetes, vascular disease, and viral or bacterial infections. In addition, changes in the localization, abundance or activity of proteases may serve as informative diagnostic or prognostic markers. This volume focuses on stomach, gut, pancreas, and liver and highlights the role of proteases in normal physiology and disease processes involving these tissues. The first chapter by Nigel W. Bunnett and Graeme S. Cottrell reviews the current knowledge about the protease-activated receptors (PARs) in gastrointestinal tissues. Starting with the mechanisms of activation, signal transduction, and regulation of PAR, their role in controlling gastrointestinal functions and the possible involvement in gastrointestinal diseases are summarized. In Chapter 2, Nikhil I. Khushalani and Nithya Ramnath review the role of matrix metalloproteases (MMPs) and their natural inhibitors, TIMPs, in different types of gastric cancer. Codice articolo 9789048171347
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Descrizione libro Paperback. Condizione: Brand New. 350 pages. 9.00x6.00x0.75 inches. In Stock. Codice articolo x-9048171342
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Descrizione libro Condizione: New. Editor(s): Lendeckel, Uwe; Hooper, N. M. Series: Proteases in Biology and Disease. Num Pages: 344 pages, biography. BIC Classification: MJH. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 19. Weight in Grams: 511. . 2010. 1st ed. Softcover of orig. ed. 2006. Paperback. . . . . Codice articolo V9789048171347
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Descrizione libro Condizione: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Codice articolo ria9789048171347_lsuk
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