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Advanced Fluorescence Reporters in Chemistry and Biology 1

Alexander P. Demchenko

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ISBN 10: 3642047009 / ISBN 13: 9783642047008
Editore: Springer-Verlag Gmbh Sep 2010, 2010
Nuovi Condizione: Neu
Da Rhein-Team Lörrach Ivano Narducci e.K. (Lörrach, Germania)

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Neuware - Fluorescence reporter is the key element of any sensing or imaging technology. Its optimal choice and implementation is very important for increasing the sensitivity, precision, multiplexing power, and also the spectral, temporal, and spatial reso- tion in different methods of research and practical analysis. Therefore, design of uorescence reporters with advanced properties is one of the most important problems. In this volume, top experts in this eld provide advanced knowledge on the design and properties of uorescent dyes. Organic dyes were the rst uorescent materials used for analytical purposes, and we observe that they retain their leading positions against strong competition of new materials - conjugated polymers, semiconductor nanocrystals, and metal chelating complexes. Recently, molecular and cellular biology got a valuable tool of organic uorophores synt- sized by cell machinery and incorporated into green uorescent protein and its analogs. Demands of various uorescence techniques operating in spectral, anisotropy, and time domains require focused design of uorescence reporters well adapted to these techniques. Near-IR spectral range becomes more and more attractive for various applications, and new dyes emitting in this range are strongly requested. Two-photonic uorescence has become one of the major tools in bioimaging, and uorescence reporters well adapted to this technique are in urgent need. These problems cannot be solved without the knowledge of fundamental principles of dye design and of physical phenomena behind their uorescence response. 389 pp. Englisch. Codice inventario libreria 9783642047008

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Titolo: Advanced Fluorescence Reporters in Chemistry...

Casa editrice: Springer-Verlag Gmbh Sep 2010

Data di pubblicazione: 2010

Legatura: Buch

Condizione libro:Neu

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Riassunto:

Fluorescence reporter is the key element of any sensing or imaging technology. Its optimal choice and implementation is very important for increasing the sensitivity, precision, multiplexing power, and also the spectral, temporal, and spatial reso- tion in different methods of research and practical analysis. Therefore, design of ?uorescence reporters with advanced properties is one of the most important problems. In this volume, top experts in this ?eld provide advanced knowledge on the design and properties of ?uorescent dyes. Organic dyes were the ?rst ?uorescent materials used for analytical purposes, and we observe that they retain their leading positions against strong competition of new materials – conjugated polymers, semiconductor nanocrystals, and metal chelating complexes. Recently, molecular and cellular biology got a valuable tool of organic ?uorophores synt- sized by cell machinery and incorporated into green ?uorescent protein and its analogs. Demands of various ?uorescence techniques operating in spectral, anisotropy, and time domains require focused design of ?uorescence reporters well adapted to these techniques. Near-IR spectral range becomes more and more attractive for various applications, and new dyes emitting in this range are strongly requested. Two-photonic ?uorescence has become one of the major tools in bioimaging, and ?uorescence reporters well adapted to this technique are in urgent need. These problems cannot be solved without the knowledge of fundamental principles of dye design and of physical phenomena behind their ?uorescence response.

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“This book is a comprehensive overview of the different types of nanoscale probes that have been and are currently being developed for sensing of analytes. The timely reference section allows the reader to locate key references to the primary literature for expansion of the material covered. ... a valuable resource that covers the synthetic, photo-physical, and theoretical aspects of this diverse field of research.” (Jeffrey T. Petty, Journal of the American Chemical Society, Vol. 133, 2011)

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