Alveolar Structure and Function (Colloquium Series on Integrated Systems Physiology)

Payne, D. Keith

ISBN 10: 161504504X ISBN 13: 9781615045044

Editore: Morgan & Claypool Life Sciences, 2012

Lingua: Inglese

Condizione: Usato - Molto buono Brossura

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Dati bibliografici

Titolo

Alveolar Structure and Function (Colloquium Series on Integrated Systems Physiology)

Editore

Morgan & Claypool Life Sciences

Data di pubblicazione

2012

Lingua

Inglese

ISBN 10

161504504X

ISBN 13

9781615045044

Rilegatura

Paperback

Condizione

Very Good

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Descrizione articolo

Riassunto

In the distal regions of the human lung, one of the most challenging problems facing a large multicellular organism is solved—ensuring an adequate supply of oxygen for aerobic tissue metabolism while removing associated waste products. Conduits for both air and blood converge at the alveolar level to match ventilation with perfusion and thus assure the free diffusion of oxygen and carbon dioxide. Despite their thin walls and their intimate relationship to the pulmonary capillary bed, the alveolus must present a barrier function robust enough to resist alveolar flooding from the hydrostatic pressures generated by the weight of the lungs and the volume of blood in the pulmonary circuit. The strategic position of the alveolar region and its vast associated capillary network ensure its importance in the synthesis and degradation of a wide range of molecules. Finally, the alveoli have evolved important immune functions vital to protecting the host from a variety of inhaled pollutants and microorganisms. Understanding alveolar structure and function is essential not only to appreciate the elegance of the human lung in its pristine state but also to understand the perturbations that underlay many lung diseases. Table of Contents: Introduction / Historical Perspectives / Lung Development / Structural Anatomy—Conducting Airways to the Alveoli / The Alveolar–Capillary Membrane and Gas Exchange / Fluid and Solute Exchange / Alveolar Defense and Clearance Mechanisms / References / Author Biography

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Book by Payne D Keith Wellikoff Adam

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