Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: Leading specialists present a comprehensive review of methods in ion channel localization, and bring together in a single book different aspects of the versatile potential of today's exciting technology. The first part of this volume provides a detailed description of the use of Green Fluorescent Protein (GFP). The second part covers a broad and complete set of issues related to GFP applications for channel localization. The third section is devoted to the latest developments in functional mapping of ion channels. With its incursion into virtually every field of biological research, the final section provides a comprehensive description of Atomic Force Microscopy. The exciting new technologies presented in this volume will interest pharmacologists, neuroscientists, physiologists, as well as molecular and cell biologists. Codice inventario libreria
Riassunto: Since the pioneering discoveries of Hodgkin, Huxley, and Katz, it has been clear that specific ion conductance pathways underlie electrical act- ity. Over the ensuing 50 years, there has been ever increasing, and occasi- ally explosive, changes in the scope of efforts to understand ion channel behavior. The introduction of patch clamp technology by Erwin Neher and Bert Sakmann about 20 years ago led to the realization of the great variety of novel ion channel species, and the subsequent revolution in cl- ing has revealed an even greater diversity of the underlying molecular entities. Today, advances in the study of ion channel structure and function c- tinue at a high pace, from angstrom resolution imaging of crystallized ch- nels to their genetic manipulations in animals. In this regard, the field is a balanced one that inquires not only what ion channel entities are there, or how they operate, but also where are these molecular electronic switches? However, this balance is not particularly well presented to the general sci- tific audience or to specialists in the field. There are plenty of wonderful and useful books and monographs, as well as conferences and meetings on v- tually every aspect of ion channel structure and function. However, we are unaware that the channel localization theme has been considered in a u- fied forum.
From the Back Cover:
Although there are many useful books on virtually every aspect of ion channel structure and function, work on channel localization-determining the specific sites of ion channels and their receptors on cells-has long been neglected. In Ion Channel Localization: Methods and Protocols, active researchers at the cutting-edge of their fields describe how to use current and developing technologies to determine the exact cell sites of such channels and receptors. With emphasis on techniques employing the unique properties of these proteins, the core topics of the book include all the major pharmacological tools for ion channel determination. Also covered are fluorescent and radioligand assays, exciting new visualization methods employing green fluorescent protein (GFP), and novel assays based on the functional properties of ion channels and receptors, as well as rapidly developing atomic force microscopy methodologies.
Comprehensive and rich in practical detail, Ion Channel Localization: Methods and Protocols brings together in a single volume detailed reviews of all the major techniques-both currently in use and in development-for localizing ion channels and receptors in cells, tissues, and organisms.
Condizione libro: New
Descrizione libro Humana Press, 2001. Condizione libro: Very Good. 2001st Edition. Former Library book. Great condition for a used book! Minimal wear. Codice libro della libreria GRP10752422
Descrizione libro Humana Press. Hardcover. Condizione libro: VERY GOOD. Very Good copy, cover and pages show some wear from reading and storage. Binding may have light creases. Lots of life left in these pages. Codice libro della libreria 2735291453
Descrizione libro Humana, USA, 2001. Hardcover. Condizione libro: Near Fine. 0896038335. Pharmaceutical company library, laminated, pictorial board hardcover. Lending record shows this book has been borrowed once only. 502 pages, index, illustrated with charts, tables and diagrams. How to use current and developing technologies to determine the location of ion channels and receptors. With emphasis on techniques employing the properties of these proteins. Includes the major tools for ion channel determination along with fluorescent and radioligand assays, visualization methods employing green fluorescent protein (GFP), and atomic force microscopy methodologies. Reviews all the major techniques. Contents as new, clean, tight and bright. Book. Codice libro della libreria 16301
Descrizione libro Humana Press, U.S.A., 2001. Hardcover. Condizione libro: Very Good Ex-Library Condition. 0896038335 | Blue/white glossy boards. Usual library markings. Clean and tightly bound. Size: 8vo - over 7¾ - 9¾" tall. Book. Codice libro della libreria B037121
Descrizione libro Humana Press, 2001. Hardcover. Condizione libro: Used: Good. Codice libro della libreria SONG0896038335
Descrizione libro Condizione libro: Very Good. Book Condition: Very Good. Codice libro della libreria 97808960383323.0
Descrizione libro Condizione libro: Brand New. Brand New Original US Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Codice libro della libreria AIND-4100
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