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Riassunto: This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investiga tion of secondary metabolism began with curiosity about the struc tures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here. This account is primarily intended to be an introduction to the biosynthesis of secondary metabolites. I have also endeavoured, however, to make the book as comprehensive as possIble. This has meant that some of the material has had to be presented in abbrevi ated form. The abbreviated material is largely confined to particular sections of the book. The paragraphs marked with a dagger (t) can be omitted by the reader wishing to acquire a general introduction to the subject. A blend of the most significant and the most recent references is cited to provide the reader with ready access to the primary litera ture. This is clearly most necessary for the material presented in abbreviated form. Relevant reviews are also cited.
Sinossi: Secondary metabolites are substances produced chiefly by micro-organisms and plants. They exhibit a wide range of biological activities and include antibiotics, such as the pencillins, and other medicinals, such as morphine. An understanding of the way these substances are made in vivo, that is to say their biosynthesis, is essential to anyone studying or working with compounds isolated from natural sources. This volume provides an account of the main experimental evidence on which current biosynthetic knowledge is based. Two introductory chapters provide the necessary background information, while the rest of the book is devoted to particular groups of secondary metabolites: polyketides, terpenes and steroids, shikimate metabolites, alkaloids and microbial metabolites containing nitrogen.
Titolo: The Biosynthesis of Secondary Metabolites
Casa editrice: Springer
Data di pubblicazione: 1981
Condizione libro: very good
Descrizione libro Chap.& H., 1981. Hardcover. Condizione libro: Gut. Sofort verfügbar / Versand am folgenden Arbeitstag / mit Rechnung / daily shipping worldwide with invoice / ex library / aus Bibliothek / Sprache: Deutsch Gewicht in Gramm: 550. Codice libro della libreria 139616