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Riassunto: This volume provides a comprehensive account of the HLA system, and draws together contributions from specialists in an extraordinarily wide range of biological, biomedical, and clinical specialities. Based on the 1991 International Histocompatibility Workshop and Conference, the premiere meeting for setting terminology and standardization in this area, this work--which is divided into two parts--reports the emerging issues in this extremely important field. The meeting itself considered the results from an enormous four year international collaborative testing program, which used 537 selected sera and 32000 panel cells from 180 ethnic groups. From this program, known HLA specificities are further analysed, subdivided, and their categorization refined and agreed. New HLA types are also identified. For the first time, the meeting used oligonucleotide probes and amplification techniques to provide an analysis of the system at the DNA level. All these results are reported in Part 1 and are not easily available elsewhere. Part 2 comprises the 199 conference papers, plenary lectures and special and mini-symposia. Many of the key areas are reviewed by leading authorities in immunogenetics, DNA analysis of the system, transplantation, disease susceptibility, immune regulation, T-cell biology, population genetics and evolution. Authoritative editors and a distinguished roster of contributors make this work is an essential resource for all serious biomedical research collections.
L'autore: Kimiyoshi Tsuji, Professor, School of Medicine, Tokai University. Miki Aizawa, Professor (Retired), Hokkaido Histopathology Center. Takehiko Sasazuki, Professor, Department of Genetics, Medical Institute of Bioregulation, Kyushu University.
Titolo: HLA 1991: Proceedings of the Eleventh ...
Casa editrice: Oxford University Press
Data di pubblicazione: 1993
Condizione libro: very good
Descrizione libro Oxford University Press, USA, 1993. Hardcover. Condizione libro: New. 1. Codice libro della libreria DADAX019262217X