Necrotizing Enterocolitis: Insights Into the Pathogenesis of This Challenging Disease (Colloquium Series on Integrated Systems Physiology: From Molecule to Function)

Michael Caplan

ISBN 10: 1615045902 / ISBN 13: 9781615045907

Editore: Morgan & Claypool Life Sciences, 2013

The book has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged. Codice articolo GOR012700987

Riassunto:

Necrotizing enterocolitis is an acute inflammatory necrosis of bowel that primarily afflicts premature infants in the neonatal intensive care unit setting. Although patients who develop this disease have high morbidity and mortality rates, the pathogenesis is poorly understood, and therefore there are no specific preventive or treatment strategies that have been clearly effective. Recent studies have suggested that the pathophysiology of necrotizing enterocolitis includes alterations in the inflammatory response leading to dysregulated pro-inflammatory signaling in premature infants, as well as abnormal intestinal bacterial colonization patterns that can activate these inflammatory pathways, and these factors are discussed in depth in the following chapters. While human milk feedings are currently the standard of care for the prevention of this challenging condition, new approaches will be described based on sound evidence that might have a significant impact for premature infants throughout the world.

Dati bibliografici

Titolo: Necrotizing Enterocolitis: Insights Into the...
Casa editrice: Morgan & Claypool Life Sciences
Data di pubblicazione: 2013
Legatura: Paperback
Condizione: Very Good