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Riassunto: First the Bad News, Then the Good News. An honored scientist, who has a fine track-record of being correct, uncovers the first powerful evidence that xray procedures are a MAJOR cause, for men and women, of Cancer AND of Ischemic Heart Disease (also called Coronary Heart Disease, Coronary Artery Disease, and Myocardial Ischemia).
These two discoveries (not previously published elsewhere) point to a safe and painless way to achieve big reductions in mortality from both diseases --- because the undeniable benefits of xray procedures can be obtained, demonstrably, at much lower levels of xray dosage. Exposure to xrays, including fluoroscopy and CT scans, is a well-established cause of structural chromosomal aberrations and other mutations, even at very low doses and dose-rates.
Because the author's two discoveries are so startling, he shares at the outset (Chapter 1) the eight reasons which combine to make him confident that the findings are scientifically sound.
The content of this book is important to everyone who has either a professional or a personal interest in understanding and preventing Cancer and Ischemic Heart Disease. These two diseases account for 45% of deaths in the USA. The book presents strong evidence that medical radiation is one of their important causes.
Like detectives, many readers ENJOY evaluating evidence of causation. They seek data-and-logic, and are not intimidated by it. Such readers will find this to be a reader-friendly book. It uses no complex statistical operations. It shows each step between the raw data and the conclusions. And, because readers will "arrive" from many different fields, it defines even basic terms and concepts.
The nature of the evidence in this book will be comprehensible not only to biomedical and public health scientists, physicians, and undergraduate students worldwide, but also to non-medical scientists, engineers, lawyers, and health activists. The book begins with a short Introduction, an Abstract, and an Executive Summary.
Nearly all physicians --- whether they be radiologists, surgeons, gynecologists, cardiovascular specialists, general practitioners, or other --- either administer or "order" medical xrays. They need to know the findings and implications of this book for the health of their patients, regarding two of the most serious diseases in the United States. One implication: The undeniable benefits of xrays need to be, and demonstrably can be, obtained at much lower dose-levels than the levels commonly in use.
Patients today, who diligently inform themselves about the causes and prevention of various ailments, may wish to talk over the discoveries in this book with their own physicians.
Scientific inquiry is often organized around the exploration of hypotheses. Evidence is presented to test the validity of the hypotheses in logical ways. While an untested hypothesis is a speculation, hypotheses which PASS appropriate tests are the very substance of scientific knowledge.
This book presents a mountain of evidence which supports the two hypotheses stated on the book's cover. The first is that medical radiation is a highly important cause (probably the principal cause) of cancer mortality in the United States during the Twentieth Century. The second is that medical radiation, received even at very low and moderate doses, is an important cause of death from Ischemic Heart Disease; the probable mechanism is radiation-induction of mutations in the coronary arteries, resulting in dysfunctional clones (mini-tumors) of smooth muscle cells.
From the Back Cover:
Some Comments about Dr. John Gofman's Earlier Work and Books.
o In 1972, Dr. Gofman shared the 1972 Stouffer Prize, one of the top
awards for research in combatting arteriosclerosis. The 1972 Prize
Committee was chaired by Professor Ulf S. von Euler, M.D., former
chairman of the Nobel Prize Committee for Physiology and Medicine. The
"The 1972 Stouffer Prize is awarded to Dr. John W. Gofman for
pioneering work on the isolation, characterization and measurement of
plasma lipoproteins, and on their relationship to arteriosclerosis.
His methods and concepts have profoundly stimulated and influenced
further research on the cause, treatment, and prevention of
Radiation and Human Health. 1981. ISBN 0-87156-275-8.
o From the Journal of the American Medical Assn., March 19, 1982,
p.1637, a review by Victor E. Archer, M.D.: "This remarkable and
important book enables any intelligent person with a high school
education to understand the complexities involved in assessing the
risks to man from low levels of ionizing radiation. Gofman not only
demonstrates his mastery of this complex subject but carefully explains
the basic concepts of epidemiology, genetics, birth defects,
carcinogenesis, radiobiology, physics, chemistry and even mathematics,
which are necessary to an understanding of the subject."
Xrays--Health Effects of Common Exams. 1985. ISBN 0-87156-838.1.
o From the New England Journal of Medicine, Feb. 6, 1986, p.393, a
review by Maurice M. Greenfield, M.D. (radiologist): "This book is
practical and important. It is destined to represent a watershed in
the controversial field of low-dose radiobiology and will be of
inestimable value to radiologists, other physicians, dentists, and
o From the American Journal of Roentgenology, April 1986, p.774, a
review by David S. Martin: "From a radiologist's point of view, this
book represents a well organized and concise attempt to quantify the
cancer risk from diagnostic xray exposures by age, gender, organ, and
examination. As such, it is a useful starting point for comparisons."
Radiation-Induced Cancer from Low-Dose Exposure. 1990. ISBN 0-932682-89-8.
o From the New England Journal of Medicine, Feb. 14, 1991, p.497, a
review by G. Theodore Davis, M.D., and Andre J. Bruwer, M.D.
(radiologist) of two books jointly: The 1990 book by Gofman (above)
and the 1990 BEIR-5 Report from the National Research Council, National
Academy Press: "Both these works agree that previous assessments of
the dangers of radiation underestimated the risk, but they reach
substantially different conclusions about the magnitude of the risk,
especially when the radiation is at lower doses (below 10 rem) and the
doses are delivered slowly ... We strongly recommend both these
excellent and timely books for physicians, engineers, and public health
officials concerned with radiation, the environment, and public health."
Preventing Breast Cancer. 1995. ISBN 0-932682-96-0 (Second Edition).
o From the Journal of the American Medical Assn. "Medical News &
Perspectives," August 2, 1995, a two-page feature (pp.367-368) by
Andrew A. Skolnick about Gofman's book: "A respected authority on the
biological effects of ionizing radiation has just published a book
claiming that the vast majority of breast cancers in the United States
were caused by ... medical xrays ..." Skolnick quotes from interviews
with the author and with critics of the book.
o On August 3, 1995, Channel 3 in Britain telecast a report ("The Xray
Effect") featuring the book's findings. The 1995 broadcast included
"John Gofman is a superb analyst and has always been at the cutting
edge of medical science, particularly when it comes to protecting
people." o - Mortimer Mendelsohn, M.D., Ph.D., then Assoc. Director of
the Radiation Effects Research Foundation (the A-Bomb Survivor Study).
"Dr. Gofman is owed a debt of gratitude by the scientific community
because he was one of the first people to raise the issue of cancer
risks from radiation exposure." o - Edward P. Radford, M.D.,
epidemiologist and Chairman of the 1980 Committee on the Biological
Effects of Ionizing Radiation (BEIR-3) of the National Academy of
Sciences, National Research Council.
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