Structural Proteomics and Its Impact on the Life Sciences

Joel L. Sussman

Editore: World Scientific Publishing Co Pte Ltd, 2008
ISBN 10: 9812772049 / ISBN 13: 9789812772046
Usato / Hardcover / Quantità: 0
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Riassunto: The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, protein protein complexes and protein drug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.

This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis. This is the first book to provide such a comprehensive coverage of a rapidly evolving field.

Contents: The Importance of Target Selection Strategies in Structural Biology (E E Abola & R C Stevens); The Impact of Structural Proteomics on Macromolecular Structure Databases (J D Watson & J M Thornton); The Impact of 3D Structures on a Protein Knowledgebase: From Proteins to Systems (U Hinz & A Bairoch); Bioinformatics of Protein Function (A M Lesk et al.); Comparative Modeling in Structural Genomics (J Moult); The Contribution of Structural Proteomics to Understanding the Function of Hypothetical Proteins (M D Suits et al.); Intrinsically Disordered Proteins (P Tompa); Metalloproteins: Structure, Conservation and Prediction of Metal Binding Sites (M Edelman et al.); The Impact of Protein Expression Methodologies on Structural Proteomics (A Chesneau et al.); Protein Complexes Assembly by Multi-Expression in Bacterial and Eukaryotic Hosts (C Romier); The Impact of Structural Proteomics on the Prediction of Protein-Protein Interactions (C Kiel & L Serrano); Cryo-Electron Microscopy in the Era of Structural Proteomics (A C Steven & D M Belnap); On NMR-based Structural Proteomics (T Szyperski); Structural Proteomics in Relation to Signaling Pathways (F Bedez et al.); The Impact of Structural Proteomics and Drug Design (Y-P Pang); Structural Proteomics of Emerging Viruses: The Example of SARS-CoV and Other Coronaviruses (R Hilgenfeld et al.); High-throughput Technologies for Structural Biology: The Protein Structure Initiative Perspective (A Joachimiak); European Structural Proteomics A Perspective (S Daenke et al.); Structural Genomics and Structural Proteomics: A Global Perspective (L Banci et al.); Policies in Structural Genomics/Structural Proteomics (J Norvell & J Berg).

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Titolo: Structural Proteomics and Its Impact on the ...
Casa editrice: World Scientific Publishing Co Pte Ltd
Data di pubblicazione: 2008
Legatura: Hardcover
Condizione libro: New

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Descrizione libro World Scientific Publishing Co Pte Ltd, Singapore, 2008. Hardback. Condizione libro: New. Language: English . Brand New Book. The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, protein-protein complexes and protein-drug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis.This is the first book to provide such a comprehensive coverage of a rapidly evolving field. Codice libro della libreria AAJ9789812772046

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Descrizione libro World Scientific Publishing Co Pte Ltd, Singapore, 2008. Hardback. Condizione libro: New. Language: English . Brand New Book. The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, protein-protein complexes and protein-drug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis. This is the first book to provide such a comprehensive coverage of a rapidly evolving field. Codice libro della libreria AAJ9789812772046

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Descrizione libro World Scientific Publishing Co Pte Ltd, Singapore, 2008. Hardback. Condizione libro: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, protein-protein complexes and protein-drug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis. This is the first book to provide such a comprehensive coverage of a rapidly evolving field. Codice libro della libreria BTE9789812772046

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Descrizione libro World Scientific Publishing Co Pte Ltd. Hardback. Condizione libro: new. BRAND NEW, Structural Proteomics and Its Impact on the Life Sciences, Joel L. Sussman, Israel Silman, The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th century. The development of high-throughput technologies that permit the solution of hundreds of 3D structures of individual proteins, protein-protein complexes and protein-drug complexes, just by one laboratory in a single year, will provide a knowledge base which will change the face of structural biology. This will have an immediate influence on medicinal chemistry and molecular pharmacology, as well as an increasing impact on such disciplines as neurobiology, developmental biology, immunology and molecular medicine.This book presents a state-of-the-art overview of the structural proteomics field, ranging from policy issues related to funding and goals, through the high-throughput procedures for protein production, to the solution of the structures of proteins and higher-order entities, via a multidisciplinary approach involving molecular biology, X-ray crystallography, NMR and electron microscopy, as well as bioinformatics analysis. This is the first book to provide such a comprehensive coverage of a rapidly evolving field. Codice libro della libreria B9789812772046

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Descrizione libro 2008. Hardcover. Condizione libro: New. Hardcover. The role played by structural proteomics in the first decade of the 21st century is equivalent to that played by the Human Genome Project in the last decade of the 20th centur.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 572 pages. 0.998. Codice libro della libreria 9789812772046

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Descrizione libro World Scientific Publishing Company, Inc. Condizione libro: New. pp. 600. Codice libro della libreria 8368688

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