Structure, Function and Regulation of TOR complexes from Yeasts to Mammals: Part A: 27 - Rilegato

Rilegato

ISBN 10: 0123815398 ISBN 13: 9780123815392

Casa editrice: Academic Press, 2010

Riassunto

Cell growth is highly regulated and is controlled by the TOR signaling network. Dysfunction of signaling pathways controlling cell growth results in cells of altered sizes and in turn causes developmental errors and a wide range of pathological conditions. An understanding of the TOR signaling network may lead to novel drugs for the treatment of, for example, cancer, diabetes, inflammation, muscle atrophy, learning disabilities, depression, obesity and aging.

There has been an explosion of knowledge in this area in recent years and this volume provides an in-depth review of our current knowledge of TOR complexes by the leaders in the field.

• Contributions from leading authorities
• Informs and updates on all the latest developments in the field

Su questo libro

L'autore:

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997. Since 1996, he has been a Director of Signal Transduction Program Area at Jonsson Comprehensive Cancer Center. Dr. Tamanoi earned his B.S. and M.S. in Biochemistry at the University of Tokyo. He received PhD in Molecular Biology at Nagoya University in 1977. He was a postdoctoral fellow at Harvard Medical School, where he worked on bacteriophage DNA replication. From 1980 to 1985, he was a senior staff investigator at Cold Spring Harbor Laboratory, where he worked on adenovirus DNA replication. From 1985 to 1993, he was an Assistant Professor and then Associate Professor at the University of Chicago, where he initiated studies on lipid modification of the Ras family proteins. His laboratory research centers on signal transduction and signal transduction inhibitors. He is currently exploring ways to deliver signal transduction inhibitors using nanoparticles.

Su questa edizione

• Editore: Academic Press
• Data di pubblicazione: 2010
• ISBN 10: 0123815398
• ISBN 13: 9780123815392
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 420
• Redattore: Hall Michael N, Tamanoi Fuyuhiko