A state-of-the-science compilation, Lipoic Acid follows the history of this potent coenzyme and the latest discoveries regarding the chemistry, biological action, and significance in energy production, antioxidant activity, and health. The book is divided into three sections:
· Section I: Discovery and Molecular Structure reviews the early studies leading to the discovery of alpha-lipoic acid and explains the molecular structure, biosynthesis, and the characterization of lipoic acid and its chemical derivatives.
· Section II: Metabolic Aspects describes in detail the human pharmacokinetics of alpha-lipoic acid including the lipoic acid-derived dehydrogenase complexes and their roles in energy metabolism. It also explains antioxidant activity and redox modulation and how lipoic acid induces Phase II detoxification enzymes through activation of Nrf2-dependent gene expression.
· Section III Clinical Aspects discusses enzyme deficiency disorders and the effects of lipoic acid on insulin. It defines lipoic acid influence on signaling pathways and AMP-activated kinase, and considers the therapeutic implications for treatment of metabolic syndromes and the improvement of mitochondrial function by lipoic acid supplementation.
Contributions from leading in
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
Spese di spedizione:
EUR 3,73
In U.S.A.
Descrizione libro Condizione: New. pp. 556. Codice articolo 26499041
Descrizione libro Condizione: New. pp. 556 Illus. This item is printed on demand. Codice articolo 7348926
Descrizione libro Condizione: New. Codice articolo 4968167-n
Descrizione libro Condizione: New. Codice articolo 4968167-n
Descrizione libro HRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000. Codice articolo FT-9781420045376
Descrizione libro HRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000. Codice articolo FT-9781420045376
Descrizione libro Hardcover. Condizione: Brand New. 1st edition. 532 pages. 9.00x6.00x1.25 inches. In Stock. Codice articolo __1420045377