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Spese di spedizione:
EUR 5,25
Da: Regno Unito a: U.S.A.
Descrizione libro paperback. Condizione: New. Language: ENG. Codice articolo 9783659116339
Descrizione libro Condizione: New. Book is in NEW condition. Codice articolo 3659116335-2-1
Descrizione libro Condizione: New. New! This book is in the same immaculate condition as when it was published. Codice articolo 353-3659116335-new
Descrizione libro Paperback or Softback. Condizione: New. Enhancement of solubility of Mebendazole by SEDDS 0.36. Book. Codice articolo BBS-9783659116339
Descrizione libro Condizione: New. Codice articolo ABLIING23Mar3113020263364
Descrizione libro PAP. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Codice articolo L0-9783659116339
Descrizione libro Condizione: New. Codice articolo I-9783659116339
Descrizione libro Condizione: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Codice articolo ria9783659116339_lsuk
Descrizione libro PF. Condizione: New. Codice articolo 6666-IUK-9783659116339
Descrizione libro Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for increasing its solubility. Various oils, surfactants and co-surfactants were screened for their suitability in the formulation of SEDDS. Based on the initial screening, Omix of Tocopherol acetate and Peceol in the ratio 6:4 and surfactant, Labrasol and co-surfactant, PEG 200 were found to be satisfactory. Five formulations were selected from pseudoternary phase diagrams and were evaluated for parameters like drug content, percentage transmittance, dilution potential, centrifugation test, in-vitro release study, emulsification time and dispersibility, emulsion droplet size, zeta potential, polydispersibility index and ex-vivo permeation studies. All the formulations exhibited a rapid emulsification rate and a good polydispersibity index. The size of the droplets as determined by zeta sizer was found to be below 300 nm. The percentage drug release from the formulations was improved compared to that of pure drug. Thus, the formulated SEDDS helped in improving the solubility and dissolution of the drug, thereby increasing its therapeutic effectiveness. 104 pp. Englisch. Codice articolo 9783659116339