Articoli correlati a Gene Vaccines
The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti:
Preface.- 1 General mechanisms of gene vaccines.- 2 Strategies to Improve DNA Vaccine Potency: HPV-associated Cervical Cancer as a Model System.- 3 Immune-activating mechanisms of replicase-based DNA and RNA vaccines and their role in immune-apoptosis.- 4 Cytokine genes as molecular adjuvants for DNA vaccines.- 5 Pharmaceutical non-viral formulations for gene vaccines.- 6 Rational design of formulated DNA vaccines: the DermaVir approach.- 7 In vivo electroporation.- 8 Electroporation-based Trigrid™ delivery system (TDS) for DNA vaccine administration.- 9 Prime Boost Regimens for Enhancing Immunity: Magnitude, Quality of Mucosal and Systemic Gene Vaccines.- 10 Intranodal genetic immunization.- 11 Immunotherapy of cancer with RNA vaccines.- 12 DNA and RNA vaccines for prophylactic and therapeutic treatment of type I allergy.- 13 Approved veterinary vaccines – paving the way to products for human use.- 14 Current status of regulations for DNA vaccines.- 15 State of the art production of antibiotic resistance-free plasmid DNA.- 16 Industrial Manufacturing of Plasmid-DNA Products for Gene Vaccination and Therapy.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
- EditoreSpringer Verlag
- Data di pubblicazione2011
- ISBN 10 3709104386
- ISBN 13 9783709104385
- RilegaturaCopertina rigida
- Numero edizione1
- Numero di pagine330
- RedattoreThalhamer Josef, Weiss Richard, Scheiblhofer Sandra
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Descrizione libro Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models.Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the 'world of naked gene vaccines', namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing 'burning questions'. 344 pp. Englisch. Codice articolo 9783709104385
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Descrizione libro Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Only updated volume on gene vaccines focus on the most promisingApproaches towards gene vaccinationApproaches close to or already in clinical use objective comparison of different methods and protocolsThe induction of antigen-specif. Codice articolo 5249531
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Descrizione libro Hardcover. Condizione: new. Hardcover. The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models.Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the world of naked gene vaccines, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing burning questions. The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Codice articolo 9783709104385
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Descrizione libro Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models.Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the 'world of naked gene vaccines', namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing 'burning questions'. Codice articolo 9783709104385
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Descrizione libro Condizione: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Codice articolo ria9783709104385_lsuk
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