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Editore: Berlin, Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: Antiquariat Bookfarm, Löbnitz, Germania
Libro
Hardcover. 331 S. Ehem. Bibliotheksexemplar mit Signatur und Stempel. GUTER Zustand, ein paar Gebrauchsspuren. Ex-library with stamp and library-signature. GOOD condition, some traces of use. 9783540690368 Sprache: Englisch Gewicht in Gramm: 550.
Editore: Springer, Germany, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: The Book Exchange, Macclesfield, Regno Unito
Libro
Hardcover. Condizione: Near Fine. No Jacket. 9783540690368. Unread hardcover, from closed pharmaceutical company library. English text. 342 pages, Subject Index, illustrated with charts, tables and diagrams. Sections: Macrolide-Based Microtubule-Stabilizing Agents - Chemistry and Structure-Activity Relationships; The Chemical Synthesis of Discodermolide; The Interaction of Microtubules with Stabilizers Characterized at Biochemical and Structural Levels; The Tubulin Binding Mode of MT Stabilizing and Destabilizing Agents Studied by NMR; The Tubulin Binding Mode of Microtubule Stabilizing Agents Studied by Electron Crystallography; Microtubule-Destabilizing Agents: Structural and Mechanistic Insights from the Interaction of Colchicine and Vinblastine with Tubulin; Molecular Modeling Approaches to Study the Binding Mode on Tubulin of Microtubule Destabilizing and Stabilizing Agents. Contents unread, looks like new, clean, tight and bright. Book.
Editore: Springer, 2009
ISBN 10: 3642435947ISBN 13: 9783642435942
Da: Anybook.com, Lincoln, Regno Unito
Libro
Condizione: Good. Volume 286. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,650grams, ISBN:9783642435942.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: Studibuch, Stuttgart, Germania
Libro
hardcover. Condizione: Sehr gut. 342 Seiten; 9783540690368.2 Sprache: Deutsch Gewicht in Gramm: 1.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: Michener & Rutledge Booksellers, Inc., Baldwin City, KS, U.S.A.
Libro
Hardcover. Condizione: Very Good+. Text clean and tight; no dust jacket; Topics in Current Chemistry 286; 0.9 x 9.3 x 6.3 Inches; 342 pages.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: booksXpress, Bayonne, NJ, U.S.A.
Libro
Hardcover. Condizione: new.
Editore: Springer, Berlin|Springer US|Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: moluna, Greven, Germania
Libro Print on Demand
Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynam.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: GreatBookPrices, Columbia, MD, U.S.A.
Libro
Condizione: New.
Editore: Springer US Okt 2023, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains by measuring or calculating their affinity to phosphopeptides. Part Three focuses on inhibitors of SH2 domains that lead the way for chemical tool development and drug discovery. Part Four describes how to evolve and engineer SH2 domains with specific binding properties, and Part Five explores how to measure the regulation of protein tyrosine phosphatase activity through allosteric binding of peptides to SH2 domains and condensation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, SH2 Domains: Functional Modules and Evolving Tools in Biology is a valuable resource for researchers, working in the biophysical and biochemical field, who want to learn more about this exciting and versatile class of regulatory and signaling domains. 396 pp. Englisch.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: Ria Christie Collections, Uxbridge, Regno Unito
Libro
Condizione: New. In.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: GreatBookPricesUK, Castle Donington, DERBY, Regno Unito
Libro
Condizione: New.
Editore: Springer US, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: AHA-BUCH GmbH, Einbeck, Germania
Libro
Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains by measuring or calculating their affinity to phosphopeptides. Part Three focuses on inhibitors of SH2 domains that lead the way for chemical tool development and drug discovery. Part Four describes how to evolve and engineer SH2 domains with specific binding properties, and Part Five explores how to measure the regulation of protein tyrosine phosphatase activity through allosteric binding of peptides to SH2 domains and condensation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, SH2 Domains: Functional Modules and Evolving Tools in Biology is a valuable resource for researchers, working in the biophysical and biochemical field, who want to learn more about this exciting and versatile class of regulatory and signaling domains.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: Basi6 International, Irving, TX, U.S.A.
Libro
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Editore: Springer-Verlag New York Inc., New York, NY, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: Grand Eagle Retail, Wilmington, DE, U.S.A.
Libro Prima edizione
Hardcover. Condizione: new. Hardcover. This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains by measuring or calculating their affinity to phosphopeptides. Part Three focuses on inhibitors of SH2 domains that lead the way for chemical tool development and drug discovery. Part Four describes how to evolve and engineer SH2 domains with specific binding properties, and Part Five explores how to measure the regulation of protein tyrosine phosphatase activity through allosteric binding of peptides to SH2 domains and condensation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, SH2 Domains: Functional Modules and Evolving Tools in Biology is a valuable resource for researchers, working in the biophysical and biochemical field, who want to learn more about this exciting and versatile class of regulatory and signaling domains. Part Four describes how to evolve and engineer SH2 domains with specific binding properties, and Part Five explores how to measure the regulation of protein tyrosine phosphatase activity through allosteric binding of peptides to SH2 domains and condensation. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: GreatBookPrices, Columbia, MD, U.S.A.
Libro
Condizione: As New. Unread book in perfect condition.
Editore: Springer, 2014
ISBN 10: 3642435947ISBN 13: 9783642435942
Da: booksXpress, Bayonne, NJ, U.S.A.
Libro
Soft Cover. Condizione: new.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: booksXpress, Bayonne, NJ, U.S.A.
Libro
Hardcover. Condizione: new.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: GreatBookPricesUK, Castle Donington, DERBY, Regno Unito
Libro
Condizione: As New. Unread book in perfect condition.
Editore: Humana Pr Inc, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: Revaluation Books, Exeter, Regno Unito
Libro
Hardcover. Condizione: Brand New. 10.00x7.01 inches. In Stock.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: Ria Christie Collections, Uxbridge, Regno Unito
Libro Print on Demand
Condizione: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Editore: Springer, 2014
ISBN 10: 3642435947ISBN 13: 9783642435942
Da: Ria Christie Collections, Uxbridge, Regno Unito
Libro Print on Demand
Condizione: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: Kennys Bookshop and Art Galleries Ltd., Galway, GY, Irlanda
Libro
Condizione: New.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: GreatBookPrices, Columbia, MD, U.S.A.
Libro
Condizione: New.
Editore: Springer, 2014
ISBN 10: 3642435947ISBN 13: 9783642435942
Da: Lucky's Textbooks, Dallas, TX, U.S.A.
Libro
Condizione: New.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: Lucky's Textbooks, Dallas, TX, U.S.A.
Libro
Condizione: New.
Editore: Springer Berlin Heidelberg Nov 2014, 2014
ISBN 10: 3642435947ISBN 13: 9783642435942
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an interdisciplinary manner to generate a time-resolved picture of the interaction of the drugs with different tubulin forms. The fourth and fifth chapters review the efforts and achievements made in the characterization of the structure of the complexes of tubulin with microtubules stabilizing agents by NMR (Chapter 4) and EM (Chapter 5). Especially evident is the discrepancy of the results obtained for epothilones, where the two techniques deliver radically different structures of the bound drug. Both NMR and EM models are, however, able to explain a consistent set of SAR data. The authors of the two chapters discuss critically the advantages and limitations of each methodology. 344 pp. Englisch.
Editore: Humana, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: ALLBOOKS1, Salisbury Plain, SA, Australia
Libro
Editore: Springer-Verlag New York Inc., New York, NY, 2023
ISBN 10: 1071633929ISBN 13: 9781071633922
Da: CitiRetail, Stevenage, Regno Unito
Libro Prima edizione
Hardcover. Condizione: new. Hardcover. This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains by measuring or calculating their affinity to phosphopeptides. Part Three focuses on inhibitors of SH2 domains that lead the way for chemical tool development and drug discovery. Part Four describes how to evolve and engineer SH2 domains with specific binding properties, and Part Five explores how to measure the regulation of protein tyrosine phosphatase activity through allosteric binding of peptides to SH2 domains and condensation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, SH2 Domains: Functional Modules and Evolving Tools in Biology is a valuable resource for researchers, working in the biophysical and biochemical field, who want to learn more about this exciting and versatile class of regulatory and signaling domains. Part Four describes how to evolve and engineer SH2 domains with specific binding properties, and Part Five explores how to measure the regulation of protein tyrosine phosphatase activity through allosteric binding of peptides to SH2 domains and condensation. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.
Editore: Springer Berlin Heidelberg, 2014
ISBN 10: 3642435947ISBN 13: 9783642435942
Da: AHA-BUCH GmbH, Einbeck, Germania
Libro
Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an interdisciplinary manner to generate a time-resolved picture of the interaction of the drugs with different tubulin forms. The fourth and fifth chapters review the efforts and achievements made in the characterization of the structure of the complexes of tubulin with microtubules stabilizing agents by NMR (Chapter 4) and EM (Chapter 5). Especially evident is the discrepancy of the results obtained for epothilones, where the two techniques deliver radically different structures of the bound drug. Both NMR and EM models are, however, able to explain a consistent set of SAR data. The authors of the two chapters discuss critically the advantages and limitations of each methodology.
Editore: Springer, 2009
ISBN 10: 3540690360ISBN 13: 9783540690368
Da: GreatBookPrices, Columbia, MD, U.S.A.
Libro
Condizione: As New. Unread book in perfect condition.