Lingua: Inglese
Editore: Marcel Dekker, New York, NY, 1995
ISBN 10: 0824788400 ISBN 13: 9780824788407
Cloth. Condizione: Near Fine. 550 pp. Tightly bound. Corners not bumped. Text is free of markings.
Da: P.C. Schmidt, Bookseller, Kettering, OH, U.S.A.
Prima edizione
Hard Cover. Condizione: Very Good. First Edition. a very good hardcover; an ex-library copy with usual markings; internally pages bright and clean; ---------- SATISFACTION GUARANTEED --------- FAST, COURTEOUS SERVICE ------ ALL ORDERS SHIPPED WITH DELIVERY CONFIRMATION; Size: 7 x 9". Ex-Library.
hardcover. Condizione: New. In shrink wrap. Looks like an interesting title!
Da: Great Matter Books, Grand Rapids, MI, U.S.A.
Hardcover. Condizione: Very Good. No Jacket. Very Good condition hardcover book, no dust jacket. Shelf wear to covers. Bumping to spine ends. Pages lightly toned and smudged at text block edges and margins, pages are otherwise clean and unmarked. All books are individually inspected and described. Never X-Library unless specifically described as such.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
hardcover. Condizione: Very Good. 2014 signed and inscribed first edition, association copy (1977 Nobel winner Roger Guillemin), 7 x 9 7/8 inches tall color pictorial hardcover, no dust jacket (as issued), illustrated with color and black-and-white diagrams and drawings, index, xii, 296 pp. Laid in is a slip reading, 'From the Private Colllection of Dr. Roger and Lucienne Guillemin, Nobel Laureate, 1977, Salk Institute, La Jolla, CA.' Roger Charles Louis Guillemin (1924-2024) was a French-American neuroscientist who received the National Medal of Science in 1976, and the Nobel Prize for Medicine in 1977 for his work on neurohormones. Very slight soiling, rubbing and edgewear to covers. On the title page, nicely signed by author Douglas Lappi and inscribed to Guillemin, widely considered the 'father of neuroendocrinology' and winner of the Nobel prize for medicine. Otherwise, a very good to near fine copy - clean, bright and unmarked. ~SP19~ [2.5P] This important reference provides information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain. Contents: Preface; 1 Introduction and History; Introduction; Identification and Distribution in Nature; Mechanism of Action; Effects on Cells and Animals; Role in Nature; Practical Applications; Bioweapons; Future Challenges; References; 2 Occurrence and Taxonomical Distribution of Ribosome-inactivating Proteins Belonging to the Ricin/Shiga Toxin Superfamily; Introduction; How to Investigate the Distribution of Proteins with an N-glycosidase Domain?; Conclusions; Acknowledgments. IntroductionFamily Sambuceae; Type 2 RIPs from Other families; Uses of nontoxic type 2 RIPs; Concluding remarks; Acknowledgment; References; 6 The Intracellular Journey of Type 2 Ribosome-inactivating Proteins; Introduction; Cell Surface Events; Endosome to TGN Sorting; From the Golgi to the ER; Reductive Separation and Destabilization of the Holotoxin Subunits; Dislocation Across the ERâ?0 embrane; Cytosolic Post-dislocation Events that Restore Catalytic Activity; Concluding Remarks; Acknowledgements; References. 7 Shiga ToxinsIntroduction; Purification of Shiga Toxins; Structure and Mechanism of Action of Shiga Toxins; Role of Shiga Toxins in the Pathogenesis of HUS; The 2011 German STEC Outbreak; References; 8 The Structure and Action of Ribosome-inactivating Proteins; Introduction; Acknowledgments; References; 9 Updated Model of the Molecular Evolution of RIP Genes; Introduction; Important Issues to be Considered in View of the Evolution of RIP Genes. Dissecting RIP Genes and RIP Gene Families by in silico Analysis of Genome and Transcriptome DataNew Insights in the Overall Phylogeny of Plant RIPs; An Updated Model of the Molecular Evolution of the Plant RIP Gene Family; What is the Evolutionary Link Between Plant and Non-Plant RIPs?; Conclusions; References; 10 Enzymology of the Ribosome-inactivating Proteins; Introduction; Ricin as RNA N-glycosidase; Role of SRL in Ribosomes; Ribosomal RNA Apurinic Site-specific Lyase Intrinsic Stability of the Ribosomes; Action of RIPs on DNA.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
EUR 118,19
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Aggiungi al carrelloCondizione: New.
Da: GreatBookPrices, Columbia, MD, U.S.A.
Condizione: New.
Da: GreatBookPrices, Columbia, MD, U.S.A.
Condizione: As New. Unread book in perfect condition.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Lingua: Inglese
Editore: John Wiley and Sons Ltd, Hoboken, 2014
ISBN 10: 1118125657 ISBN 13: 9781118125656
Da: Grand Eagle Retail, Bensenville, IL, U.S.A.
Prima edizione
Hardcover. Condizione: new. Hardcover. This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain. This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 141,28
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Aggiungi al carrelloCondizione: As New. Unread book in perfect condition.
Condizione: New. pp. 328.
Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 144,94
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Aggiungi al carrelloCondizione: New.
Condizione: Used. pp. 328 1st Edition.
EUR 164,37
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EUR 171,67
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Aggiungi al carrelloCondizione: New. Brand new! Please provide a physical shipping address.
Da: Kennys Bookshop and Art Galleries Ltd., Galway, GY, Irlanda
Prima edizione
EUR 170,06
Quantità: 15 disponibili
Aggiungi al carrelloCondizione: New. This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Editor(s): Stirpe, Fiorenzo; Lappi, Douglas. Num Pages: 328 pages, black & white illustrations, black & white line drawings, black & white tables, figures, BIC Classification: MJCM; PSBC. Category: (P) Professional & Vocational. Dimension: 251 x 169 x 20. Weight in Grams: 812. . 2014. 1st Edition. Hardcover. . . . .
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EUR 182,36
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Lingua: Inglese
Editore: John Wiley and Sons Ltd, Hoboken, 2014
ISBN 10: 1118125657 ISBN 13: 9781118125656
Da: CitiRetail, Stevenage, Regno Unito
Prima edizione
EUR 168,99
Quantità: 1 disponibili
Aggiungi al carrelloHardcover. Condizione: new. Hardcover. This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain. This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.
EUR 159,09
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Aggiungi al carrelloCondizione: New. Fiorenzo Stirpe is Professor Emeritus at the Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.Douglas A. Lappi is the President and Chief Scientific Officer of Advanced Targeting Systems, USA.Ribosome-inactivat.
Condizione: New. This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Editor(s): Stirpe, Fiorenzo; Lappi, Douglas. Num Pages: 328 pages, black & white illustrations, black & white line drawings, black & white tables, figures, BIC Classification: MJCM; PSBC. Category: (P) Professional & Vocational. Dimension: 251 x 169 x 20. Weight in Grams: 812. . 2014. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.
EUR 219,03
Quantità: 1 disponibili
Aggiungi al carrelloPaperback. Condizione: Brand New. reprint edition. 328 pages. 9.45x6.30x0.73 inches. In Stock.
Da: Kennys Bookshop and Art Galleries Ltd., Galway, GY, Irlanda
EUR 230,48
Quantità: 15 disponibili
Aggiungi al carrelloCondizione: New. Gives a treatment of the highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals. This book explains the theory and techniques of using targeted toxins experimentally. Editor(s): Wiley, Ronald G.; Lappi, Douglas. Num Pages: 312 pages, biography. Category: (G) General (US: Trade); (P) Professional & Vocational; (U) Tertiary Education (US: College). Dimension: 235 x 155 x 21. Weight in Grams: 654. . 2005. Hardback. . . . .