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Deutsche Erstausgabe. Gr.8°. 1 Blatt, 454 Seiten, 1 Blatt, mit zahlreichen z.T. blattgrossen Abbildungen im Text auf Kunstdruckpapier (davon ein Frontispiz: Ein mit dem "Very Large Array" in Soccoro (New Mexico) aufgenommenes Radiobild der elliptischen Riesengalaxie Messier 87). Illustrierter Original-Pappband (Umschlagmotiv: Eine von der Seite gesehene Spiralgalaxie, der Sombreronebel (M 104/ NGC 4594). Gutes, sauberes Exemplar. Beiliegend: 4 Zeitungsausschnitte zu diesem Buch, Ephemera.

Broschiert. Condizione: Gut. 28x21cm; XVI, 470 S. Broschiert. 617 Ill. u. graph. Darst. Zustand: Gut bis Sehr Gut min. gebräunt (Innen); Einband (Außen) hat geringe Gebrauchsspuren; * Die Photos sind original von uns erstellt worden, u.a. erkennbar an einem kleinen weißen Stück Papier im oberen Schnitt. Ab und an verwenden Suchmaschinen Verlagsphotos, bei den Portalen selbst, werden aber nur unsere Originalphotos gezeigt.

Condizione: guter Zustand. Kl. Stempel im Vorsatz. Mit hs. Widmung d. Verfassers auf d. Titelbl.

VI, 274 S. 240 Ill. (z.T. farb.) u. graph. Darst. 4° quer. Bibl.- Einbd. Zustand: Bibl.-Ex., befriedigend erhalten.

Karton. Condizione: Sehr gut. Zust: Gutes Exemplar. 454 S. Deutsch 876g.

XVI, 597 SS., 1 Bl. Mit einigen Textfiguren. Gr. 8°. Opbd.

Gebunden. Condizione: New.

Taschenbuch. Condizione: Neu. Neuware - This text is based on a lecture course given by the authors in the framework of Oberwolfach Seminars at the Mathematisches Forschungsinstitut Oberwolfach in May, 2013. It is intended to serve as a thorough introduction to the rapidly developing field of positional games. This area constitutes an important branch of combinatorics, whose aim it is to systematically develop an extensive mathematical basis for a variety of two player perfect information games. These ranges from such popular games as Tic-Tac-Toe and Hex to purely abstract games played on graphs and hypergraphs. The subject of positional games is strongly related to several other branches of combinatorics such as Ramsey theory, extremal graph and set theory, and the probabilistic method. These notes cover a variety of topics in positional games, including both classical results and recent important developments. They are presented in an accessible way and are accompanied by exercises of varying difficulty, helping the readerto better understand the theory.The text will benefit both researchers and graduate students in combinatorics and adjacent fields.

Taschenbuch. Condizione: Sehr gut. Gebraucht - Sehr gut SG - leichte Beschädigungen, Verschmutzungen, ungelesenes Mängelexemplar, gestempelt, Versand Büchersendung - La construction en maçonnerie constitue généralement le premier des exercices de construction pendant les études. Les principes de base de mesure, de construction et d assemblage des composants sont développés sur des constructions en maçonnerie simple.

Condizione: New. Linear algebra is one of the most important branches of mathematics - important because of its many applications to other areas of mathematics, and important because it contains a wealth of ideas and results which are basic to pure mathematics. This book gi.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This is the first volume of a collection of essays focusing on progress in tsunami science since the great tsunami of 26 December. A magnitude Mw 9.1 earthquake (third strongest ever instrumentally recorded) generated a global tsunami that killed about 230,000 people along the coasts of 14 countries in the Indian Ocean and propagated as far as the North Pacific and North Atlantic.Since then, various countries from around the globe contributed major funding to tsunami research and mitigation, enabling the installation of hundreds of new high-precision instruments, the development of new technology and the establishment of more modern communication systems. As a result, incredible progress has been achieved in tsunami research and operation during the ten years after the 2004 Indian Ocean tsunami.The papers presented in this first of two special volumes of Pure and Applied Geophysics reflect the state of tsunami science during this time. Eight papers are related to casestudies highlighting regional hazards around the globe, while five papers record progress in tsunami warning systems. Benchmark studies that describe the accuracy of numerical models for tsunami impact, as well as a variety of inundation and generation studies, are presented by 7 additional papers.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering.

Taschenbuch. Condizione: Neu. Neuware - Many effective analgesic drugs are available for the relief of acute pain, but their clinical use is widely regarded as being inadequate. The reasons cited for this include concern about the adverse effects of opioids and also insufficient adjustment of therapy to the patient's needs. Non-opioid anal gesics are the staple drugs for mild to moderate pain and are generally better tolerated than opioid drugs. Differences exist, however, among the non-opioid analgesics which affect the choice of drug for individual pa tients and specific acutely painful conditions. In an associated symposium of the 7th International Symposium: The Pain Clinic, held in Istanbul, Turkey, the ways were discussed in which treatment with non-opioid analgesics can be tailored to meet the needs of individual patients with acute pain. The highlights of this Hoechst sympo sium, emphasize the distinctions between the non-steroidal anti-inflamma tory drugs, and the non-acidic antipyretic analgesics, particularly dipyrone. 9 Mechanisms of action of non-opioid analgesics Professor F. C. Tulunay, M.D. Ankara, Turkey The non-opioid analgesics are among the oldest class of synthetic drugs still in widespread clinical use. They can be divided into the non-steroidal anti-inflammatory drugs (NSAIDs), such as acetylsalicylic acid, and the non-acidic, antipyretic analgesics, paracetamol and dipyrone. The pharma cology of these various agents will be reviewed briefly.

Condizione: New. This integrated book begins by discussing Fourier series, Hilbert spaces and the Fourier transform on the real line, and then turns to the heart of the text, geometric considerations. The concept of orthogonality weaves the material into a coherent whole.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book provides multidisciplinary reviews of the mechanism of action and uses of methotrexate in the treatment of cancer, psoriasis, gynecologic and inflammatory diseases. The intended audience is composed of clinicians involved in the care of patients suffering from oncologic, gynecologic, rheumatic diseases as well as scientists involved in research into the pathogenesis and treatment of these diseases. This book is unique in that it provides a single, state-of-the-art source for information regarding the mechanism and use of methotrexate in many different areas of medicine.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - In November 1998 many of the key leaders of new drug discovery for inflammatory diseases gathered at Hershey, Pennsylvania for the 9th International Conference of the Inflammation Research Association. The Conference was held over a five day period and provided a stimulating environment for the open exchange of important advances in basic inflammation research as well as new drug discovery and development. This book encompasses some of the highlights of several presentations made at the Conference. It contains some of the latest and important developments in the field of inflammation research. Topics include the status of eotaxin and chemokines in asthma and allergy, signal transduction and regulation of diverse mediators such as the JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well as regulators of AP-1, macrophage metalloproteinases, lymphotoxin and further insights into the role of MCP-1 in disease. Also discussed are drug targets in rheumatoid and osteoarthritis, fibrotic diseases,.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The subject of nonlinear partial differential equations is experiencing a period of intense activity in the study of systems underlying basic theories in geometry, topology and physics. These mathematical models share the property of being derived from variational principles. Understanding the structure of critical configurations and the dynamics of the corresponding evolution problems is of fundamental importance for the development of the physical theories and their applications. This volume contains survey lectures in four different areas, delivered by leading resarchers at the 1995 Barrett Lectures held at The University of Tennessee: nonlinear hyperbolic systems arising in field theory and relativity (S. Klainerman); harmonic maps from Minkowski spacetime (M. Struwe); dynamics of vortices in the Ginzburg-Landau model of superconductivity (F.-H. Lin); the Seiberg-Witten equations and their application to problems in four-dimensional topology (R. Fintushel). Most of this material has not previously been available in survey form. These lectures provide an up-to-date overview and an introduction to the research literature in each of these areas, which should prove useful to researchers and graduate students in mathematical physics, partial differential equations, differential geometry and topology.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The present volume summarizes the state of information on chemokines focussing on skin diseases. The first three chapters deal with the structure and molecular biology of chemokines and their receptors. The following three review information on the interaction of chemokines with lymphocytes, mast cells and eosinophilic granulocytes. One chapter deals with the expression of chemokines in several inflammatory skin diseases. The final chapter reports on in vitro evidence for a growth-promoting activity of chemokines in skin-derived tumor cells. The volume is of use for the basic scientist interested in practical aspects and for the physician in search for basic mechanisms of skin diseases.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorticoid biology from the seminal description of glucocorticoid insufficiency by Thomas Addison in the mid-19th century, up to current advances in elucidating the molecular basis of glucocorticoid action. Important discoveries are presented, as well as milestones in drug development, a survey of current clinical practice, and prospects for novel glucocorticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book features an up-to-date analysis of the epidemiology of asthma in children and adults, the role of steroids in asthma management and new and novel asthma therapies. The book addresses clinicians and basic scientists with an interest in asthma epidemiology, steroids and future therapies. It is also of interest to clinical and non-clinical teachers in academic disciplines relating to respiratory disease.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Allergic skin diseases belong to the most common dermatoses. This book deals with fundamental (in particular immunological aspects) as well as clinical symptoms and therapeutic strategies of the allergic skin diseases. Cells involved in the pathomechanisms of allergic skin disease are described in individual chapters. The allergic skin diseases which will be discussed are atopic dermatitis, being the chronic inflammatory skin disease with the highest prevalence, allergic contact dermatitis with special focus on contact dermatitis from cosmetics, being the most frequent cause of contact dermatitis and occupational contact dermatitis. The broad ethiology of urticaria and the value of several therapeutic strategies will be explained. The chapter on drug allergy will deal with the variety of symptoms and the difficulties concerning in vitro and in vivo diagnosis. The book is of great interest to clinicians working in the field of dermatology, allergology, pediatrics and even general practitioners.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Important clinical issues as the outcome of long term treatment with antidepressants, the time of onset of the antidepressant response and the limitations of the antidepressants currently available are covered in this monograph. Leading researchers in the area of clinical and experimental psychopharmacology critically assess the progress in their specialist fields. The mechanisms of action of antidepressants are considered, followed by clinical research into the role of the hypothalamic-pituitary-adrenal axis and the immune system in the biology of depression and in response to treatment. The final chapter deals with the important chemical entities now undergoing development as antidepressants. The purpose of this monograph is not only to inform but also to stimulate research into the biology of depression and the mechanisms behind the action of effective antidepressants. This monograph is of interest to psychiatrists, psychologists, pharmacologists, neuroscientists and endocrinologists.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book is a comprehensive review of the structure/function and biology of molecules belonging to the TGF-ß superfamily. Because molecules in this family have very diverse biological roles the editors have chosen to focus on the parts they play in the specific areas of inflammation and wound/fracture healing. Whilst molecules in the TGF-ß superfamily have been extensively studied, there are few, if any, publications which have taken a broad perspective on this family, most having chosen to focus on just one very small area. This book is therefore unusual in that it offers a comprehensive overview of the current state of the field, providing both in-depth and essential background material suitable for both clinicians and scientists alike.

Condizione: New. This book provides multidisciplinary reviews of the mechanism of action and uses of methotrexate in the treatment of cancer, psoriasis, gynecologic and inflammatory diseases. The intended audience is composed of clinicians involved in the .

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Linear algebra is one of the most important branches of mathematics - important because of its many applications to other areas of mathematics, and important because it contains a wealth of ideas and results which are basic to pure mathematics. This book gives an introduction to linear algebra, and develops and proves its fundamental properties and theorems taking a pure mathematical approach - linear algebra contains some fine pure mathematics. Main topics: - vector spaces and algebras, dimension, linear maps, direct sums, and (briefly) exact sequences - matrices and their connections with linear maps, determinants (properties proved using some elementary group theory), and linear equations - Cayley-Hamilton and Jordan theorems leading to the spectrum of a linear map - this provides a geometric-type description of these maps - Hermitian and inner product spaces introducing some metric properties (distance, perpendicularity etc.) into the theory, also unitary and orthogonal maps and matrices - applications to finite fields, mathematical coding theory, finite matrix groups, the geometry of quadratic forms, quaternions and Cayley numbers, and some basic group representation theory A large number of examples, exercises and problems are provided. Answers and/or sketch solutions to all of the problems are given in an appendix. Some of these are theoretical and some numerical, both types are important. No particular computer algebra package is discussed but a number of the exercises are intended to be solved using one of these packages chosen by the reader.The approach is pure-mathematical, and the intended readership is undergraduate mathematicians, also anyone who requires a more than basic understanding of the subject. This book will be most useful for a 'second course' in linear algebra, that is for students that have seen some elementary matrix algebra. But as all terms are defined from scratch, the book can be used for a 'first course' for more advanced students.

Condizione: New. Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorti.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The inducible isoforms of the enzymes cyclooxygenase (COX 2), nitric oxide synthase (iNOS) and heme oxygenase 1 (HO-1) have generated great interest as possible therapeutic targets in inflammation. This book is the first publication to address the importance of all three enzymes and the consequences of their interactions to the inflammatory process. The book brings together overviews by leading researchers in the field of the current status of knowledge of COX, NOS and HO in inflammation. These overviews cover a series of new concepts in the mechanism of inflammation. Topics include inducible enzyme involvement in inflammatory processes including the role in vascular permeability, leukocycte migration, granuloma formation, angiogenesis, neuroinflammation and algesia. New findings from transgenic animal models are reviewed. Other chapters address the importance of these enzymes in inflammatory disease states including rheumatoid arthritis, atherosclerosis and multiple sclerosis. The possibility of selective inhibitors or inducers of COX, NOS and HO, and their use in the clinic is discussed. The subject matter of this book is of interest to rheumatologists, pathologists, pharmacologists, neuroscientists and anyone with an academic interest in the mechanisms of inflammation.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Nitric oxide is an endogenously produced gas with a wide range of biological effects and has been implicated in many physiological and pathophysiological processes. It is released by many cell types in various organs but is particularly important in the maintenance of normal lung function. Nitric oxide in exhaled breath has been identified as a marker for lung disease in some patients. Thus, it is appropriate to consider the lung separately for the role and functioning of nitric oxide. The authors identify key areas in the history, biochemistry, physiology, pathophysiology, immunology and clinical applications of nitric oxide in the lung. The contents of this book will be of particular importance to scientists and clinicians with an interest in lung disease. Moreover, the authors encompass state of the art opinions of and rational for the therapeutic potential of nitric oxide and its inhibitors.