springer japan mrz 2018 (21 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book overviews environmental issues 4 years after the Fukushima nuclear accident, covering a wide range of areas related to radiation and radioactivity. The topics discussed are necessary to make clear the relationship between the results of research and Fukushima's revitalized future. The chapters are divided into four parts: Part 1 presents the identification of radionuclides in soil and migration of radionuclides in the terrestrial environment; Part 2 describes the safety decontamination system and treatment of radioactive waste; Part 3 explains the development of the system of measurement of environmental radiation and evaluation of external exposure; and Part 4 discusses the identification of radionuclides in farm products, control of root uptake, identification of decreasing radionuclides by food processing, and evaluation of internal exposure. Since the accident at the Tokyo Electric Power Company's Fukushima Daiichi nuclear power station in 2011, gradual steps have been taken toward environmental recovery in the area. However, there are still many issues that need to be tackled in order to achieve the full revitalization of Fukushima. These issues encompass many different disciplines such as economics, psychology, and sociology. In this kind of situation, the role of science in relation to radiation and radioactivity is especially important. This book aims to contribute to planning countermeasures against nuclear disasters in the future. It will be of particular interest to governmental officials who are engaged with the Fukushima nuclear accident; researchers, including those in international sectors, who are interested in radiological issues; and those who need comprehensive and reliable information about the Fukushima accident. 248 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book covers seismic probabilistic risk assessment (S-PRA) and related studies which have become more important to increase the safety of nuclear facilities against earthquakes and tsunamis in the face of the many uncertainties after the Fukushima accident. The topics are (1) Active faults and active tectonics important for seismic hazard assessment of nuclear facilities,(2) Seismic source modeling and simulation and modeling techniques indispensable for strong ground motion prediction, and (3) PRA with external hazard and risk communication. The Fukushima accident has showed us the limitations of the deterministic evaluation approach to external events (an earthquake and tsunami) in which there are many uncertainties. Furthermore, public anxiety regarding nuclear safety because of an unexpected threat caused by an earthquake or tsunami is growing. The current policy on the estimation of the design basis of ground motion as well as tsunami height still has not been improved following the Fukushima accident. In particular, the risk concept in a nuclear system regarding seismic motion and a tsunami beyond the design basis is indispensable. Therefore, research and development for PRA enhancing nuclear safety are being actively pursued not only in Japan but also worldwide. This book provides an opportunity for readers to consider the future direction of nuclear safety vis-à-vis natural disasters. 192 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book brings together a number of contributions examining how changes associated with economic globalization have contributed to the creation of new pressures on, and expectations of, those fields of law connected to the regulation of cross-border commercial transactions. These new demands of law - in particular, that it be more agile or 'flexible' in regulating the economy - have prompted lawmakers and regulators in multiple jurisdictions to adopt a range of new regulatory techniques and legal forms to respond to this challenge. In many cases, these adaptations in law have entailed compromising traditional legal principles, such as legal certainty, in favor of empowering regulators with greater discretion than has traditionally been permitted in modern law. This change raises important questions about the meaning of fairness (certainty or flexibility), as well as the relationship between the public and private good. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This edited volume makes a contribution to the literature on happiness research by compiling studies based on cross-national research and from diverse academic disciplines. The book is distinctive in that it contains both theoretical and empirical analyses, investigating relationship between causes of happiness and economic behavior relating to employment, consumption, and saving. Most notably, it is one of the first studies in this subject area that analyzes micro data collected in Europe, US and Japan with information on respondents' attributes and their economic behavior, as well as in measuring inter-temporal happiness by principal factor analysis. Research findings in this volume shed new light on public policies for a number of areas such as employment, family, social welfare, urban and regional planning, and culture. The book draws on a collaborative research project between five institutions of higher education in France, UK, Germany, Switzerland, Belgium, and Japan that lasted for two years. 364 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a collection of cutting-edge studies on the functions and mechanisms of glycosylation in cancers. Along with progress in genomics and proteomics, new findings in the significance of these complex carbohydrates, through the regulation of cell signals, have been elucidated in a wide variety of biological events. This volume provides a comprehensive summary of glycosignals and their involvement in cancer, covering numerous topics such as glycosylation machineries, regulation of phenotypes, cell signaling, immune regulation, complex carbohydrate organization, and clinical applications. The contents have been organized to promote ready understanding, covering basic to clinical research and studies on micromolecules, to animal/human cells and tissues. This book is an essential read for students and young researchers interested in cancers and carbohydrates. Specialists in glycobiology will also benefit from the new results and approaches detailed here, which provide insights into future directions of functional studies of sugar chains in both basic and applied research. 228 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this monograph, the importance of fluctuations forbiological reactions is discussed from various points of view. Understandingthe biological reactions at the molecular level is one of the major targets inmany scientific fields, including not only basic biology but also physics,physical chemistry, and medical science. One of the key factors in the processis 'fluctuation'. Thermal energy causes biological molecules to be in constantfluctuation even while they are carrying out their biological functions. How dobiological systems overcome the thermal fluctuations to realize thephysiologically relevant reactions Scientists in a number of fields-physics,chemistry, pharmacology, medicine, and others-have contributed chapters thatelucidate the nature of the fluctuations and the relationship betweenfluctuations and biological functions. The fluctuations discussed in this volumeare detected by the transient grating method, nuclear magnetic resonance, X-raydiffraction and scattering, and computer simulation, among other methods. Thebook presents various results of the studies of fluctuations in biologicalprocesses that were obtained with these methods by the leading scientists intheir fields. 284 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this thesis theauthor contributes to the analysis of neutrino beam data collected between 2010and 2013 to identifynimi nieevents at the Super-Kamiokande detector. In particular,the author improves the pion-nucleus interaction uncertainty, which is one ofthe dominant systematic error sources in T2K neutrino oscillation measurement.In the thesis, the measurement ofnimi nieoscillation in the T2K (Tokai toKamioka) experiment is presented and a new constraint on dCPis obtained. Thismeasurement and the analysis establish, at greater than 5s significance, theobservation ofnimi nie oscillation for the first time in the world. Combiningthe T2Knimi nie oscillation measurement with the latest findings on oscillationparameters including the world average value ofth13from reactor experiments,the constraint on the value ofdCPat the 90% confidence level is obtained.This constraint ondCPis an important step towards the discovery of CPviolation in the lepton sector. 216 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents an in-depth, novel, and mathematically rigorous treatment of the modern classical theory of value based on the spectral analysis of the price-profit-wage rate system. The classical theory is also subjected to empirical testing to show its logical consistency and explanatory content with respect to observed phenomena and key economic policy issues related to various multiplier processes. In this context, there is an examination of the trajectories of relative prices when the distributive variables change, both theoretically and empirically, using actual input-output data from a number of quite diverse economies. It is suggested that the actual economies do not behave like the parable of a one-commodity world of the traditional neoclassical theory, which theorizes the relative scarcities of 'goods and production factors' as the fundamental determinants of relative prices and their movement. By contrast, the results of the empirical analysis are fully consistent with the modern classical theory, which makes the intersectoral structure of production and the way in which net output is distributed amongst its claimants the fundamental determinants of price magnitudes. At the same time, however, these results indicate that only a few vertically integrated industries ('industry core' or 'hyper-basic industries') are enough to shape the behaviour of the entire economy in the case of a disturbance. This fact is reduced to the skew distribution of the eigenvalues of the matrices of vertically integrated technical coefficients and reveals that, across countries and over time, the effective dimensions of actual economies are surprisingly low. Normal 0 false false false EN-US JA X-NONE /> 256 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides simplified principles of surgical anatomy for colorectal cancers with sophisticated drawings, standard laparoscopic procedures with striking photographs and illustrations, and advanced procedures such as lateral pelvic node dissection and 'down to top' or 'reverse' total mesorectal excision.Oncological safety as well as minimum invasiveness of laparoscopic surgery for colorectal cancer has been acknowledged worldwide, based on long-term outcomes of several randomized controlled trials comparing laparoscopic surgery and open surgery. Developments in optical devices have provided us with a magnified clear vision of fine anatomical structures, facilitating our understanding of surgical anatomy and surgical procedures have been refined and improved accordingly.All these topics are presented in this book-valuable for surgical residents and experts eager to learn more about laparoscopic colorectal surgery-and readers will be enlightened by a new paradigm for 'lap-enhanced surgical anatomy'. Therefore this volume will greatly benefit not only colorectal surgeons but also general surgeons as well as gastroenterologists and oncologists. 248 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes three years of extensive research conducted in Sri Lanka, Indonesia and Vietnam as part of the CECAR - Asia project, which was intended to enhance resilience to climate and ecosystem changes by developing mosaic systems to strengthen resilience of bio-production systems through the integration of large-scale modern agriculture systems with traditional, decentralized small-scale systems. The book starts with climate downscaling and impact assessment in rural Asia, and then explores various adaptation options and measures by utilizing modern science and traditional knowledge including home garden systems and ancient irrigation systems. The book subsequently examines the influence of climatic and ecological changes and the vulnerability of social economies from quantitative and qualitative standpoints, applying econometric and statistical models in agriculture communities of Asia to do so. The main goal of all chapters and case studies presented here is to identify the merits of applying organic methods to both commercial large-scale production and traditional production to strengthen social resilience and promote sustainable development. Especially at a time when modern agriculture systems are highly optimized but run the risk of failure due to changes in the climate and ecosystem, this book offers viable approaches to developing an integrated framework of modern and traditional systems to enhance productivity and total system resilience, as illustrated in various case studies. 204 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers a much-needed practical and conceptual guide for various pro-environmental behaviors. Written by an expert in both the environmental psychology and engineering fields, the book presents an overview of various pro-environmental behaviors (Chapter 1), the psychological background of behaviors (Chapters 2 and 3), how to survey and understand pro-environmental behaviors using questionnaires (Chapter 4) and how to know the actual environmental burdens derived by each behavior using life-cycle assessment (LCA) (Chapter 5), and measures to foster the behaviors and selected case studies for practitioners (Chapter 6). Readers will find Chapters 1, 4, and 5 particularly unique and useful; they provide an overview of many environmental behaviors and also the practical academic tools for analyzing environmental behaviors, such as questionnaire procedures, questions lists ('scales' in psychology), statistical tools, software, LCA methodologies, and databases.The book addresses the needs of academics and practitioners and is well suited as a textbook and reference guide for those studying or working in environmental engineering (systematic research), social psychology (environmental psychology), environmental education, and sustainability science. Policymakers will find the questionnaire list useful, as it can help them to grasp citizens' environmental concerns and actual behaviors. The behavior list and LCA can be used to make manuals or guidelines for citizens to enhance environmental behaviors, and the case studies provide an informative basis for designing programs and workshops for citizens.Although the field of 'pro-environmental behaviors' has been intensively dealt with by European researchers, their approaches have largely been limited to psychological viewpoints and program (education) development through small case studies. Further, the target behaviors are often limited to recycling and energy/water savings.In contrast, this book provides the first introduction to pro-environmental behaviors as a whole. As pro-environmental behaviors have become increasingly important not only in developed but also in developing countries, this publication represents a timely resource for the growing number of researchers exploring pro-environment behaviors. 180 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma). Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists. 256 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Going from the philosophy and concepts to the implementation and user study, this book presents an excellent overview of Japan's contemporary technical challenges in the field of human-computer interaction. The next information era will be one in which information is used to cultivate human and social potential. Driven by this vision, the outcomes provided in this work were accomplished as challenges to establish basic technologies for achieving harmony between human beings and the information environment by integrating element technologies including real-space communication, human interfaces, and media processing. Ranging from the neuro-cognitive level to the field trial, the research activities integrated novel perceptual technologies that even exceed human ability to sense, capture, and affect the real world.This book grew out of one of the CREST research areas funded by the Japan Science and Technology Agency. The theme of the project is 'the creation of human-harmonized information technology for convivial society', where 17 research teams aimed at a common goal. The project promotes a trans-disciplinary approach featuring (1) recognition and comprehension of human behaviors and real-space contexts by utilizing sensor networks and ubiquitous computing, (2) technologies for facilitating man-machine communication by utilizing robots and ubiquitous networks, and (3) content technologies for analyzing, mining, integrating, and structuring multimedia data including those in text, voice, music, and images.This is the first of two volumes, which is contributed by nine team leaders. Besides describing the technical challenges, each contribution lays much weight on discussing the philosophy, concepts, and the implications underlying the project. This work will provide researchers and practitioners in the related areas with an excellent opportunity to find interesting new developments and to think about the relationship between human and information technology. 312 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents recent advances in translational research on muscular dystrophy (MD) to physicians and researchers, including cutting-edge research on the disease such as regenerative medicine, next-generation DNA sequencing, and nucleic acid therapies. It also describes the current systems for clinical trials and MD patient databases, resources, which will support the early realization of clinical application and improve patients' quality of life. MD is the one of the most widely known inherited neuromuscular diseases and is classified into diverse types by symptoms, age of onset, mode of inheritance, and clinical progression. With the development of molecular biology, the occurrence mechanisms of each type of MD are gradually being elucidated. Although there is no known permanent cure yet, the stage of treatment research has now advanced to clinical trials. 208 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the first comprehensive book on information geometry, written by the founder of the field. It begins with an elementary introduction to dualistic geometry and proceeds to a wide range of applications, covering information science, engineering, and neuroscience. It consists of four parts, which on the whole can be read independently. A manifold with a divergence function is first introduced, leading directly to dualistic structure, the heart of information geometry. This part (Part I) can be apprehended without any knowledge of differential geometry. An intuitive explanation of modern differential geometry then follows in Part II, although the book is for the most part understandable without modern differential geometry. Information geometry of statistical inference, including time series analysis and semiparametric estimation (the Neyman-Scott problem), is demonstrated concisely in Part III. Applications addressed in Part IV include hot current topics in machine learning, signal processing, optimization, and neural networks. The book is interdisciplinary, connecting mathematics, information sciences, physics, and neurosciences, inviting readers to a new world of information and geometry. This book is highly recommended to graduate students and researchers who seek new mathematical methods and tools useful in their own fields. 388 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a collection of important contributions by Japanese researchers and their coauthors to present current advances in behavioral economics and finance, particularly in relation to decision making and human well-being. The topics covered in this volume include decision making under the conditions of inter-temporal choices, risk and social relations, happiness and the neuro-scientific/biological basis of behavior. The book includes works of research, both theoretical and empirical, on time discounting, time preferences, risk aversion, altruism, social status, happiness, addiction, limited attention and health and financial investments. The authors of the chapters add supplementary discussions to survey more recent advances on related topics or to provide detailed information that were abbreviated in the original publications. The addenda will enable readers to deepen their understanding of decision making and human well-being. 740 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume of proceedings includes 32 original contributions presented at the 12th International Symposium on Distributed Autonomous Robotic Systems (DARS 2014), held in November 2014. The selected papers in this volume are authored by leading researchers from Asia, Australia, Europe, and the Americas, thereby providing a broad coverage and perspective of the state-of-the-art technologies, algorithms, system architectures, and applications in distributed robotic systems. 492 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of this book is to review the latest findings on musculoskeletal disease associated with diabetes. It has been increasingly recognized that maintaining skeletal health is an important factor in achieving longevity in healthy subjects. Diabetes has been established as a disease independently associated with sarcopenia and increased risk of bone fracture resulting from osteoporosis; therefore, it is reasonable to maintain that musculoskeletal health is important in preserving good health. As either bone or muscle is intimately involved in the regulation of metabolic status, keeping the musculoskeletal system healthy is important for improving abnormal glucose metabolism toward normal levels and is vital, as well, for maintaining normal activities of daily living. Muscle is a target of insulin for enhancing the entry of glucose; thus it is conceivable that sarcopenia and muscle containing fat streaks causes insulin resistance in diabetic patients. Furthermore, bone is an organ that regulates Ca and Pi levels in serum by releasing or resorbing Ca and Pi to and from bone tissue. It is now known that bone is a definitive endocrine organ for regulating glucose metabolism and Pi metabolism by secreting osteocalcin and FGF-23 from osteocytes/osteoblasts. Readers will learn of the recent findings in this area, and this book will benefit physicians who deal with diabetes, particularly orthopedists and bone specialists, as well as all physical therapists. 308 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although several of their essential physiological roles have been revealed, many unknown and so far not fully understood functions have remained. In humans, there are eight active isozymes having distinct tissue and subcellular distribution patterns with different substrates and physiological roles. Accordingly, aberrant regulation of the enzyme reactions or expression may lead to or has been implicated in various pathologies including neurodegeneration, fibrosis, cancer, inflammation, celiac disease, and hemostasis disorders.To provide those who are new to the field with basic knowledge and recent information on transglutaminase structures and reactions, the mechanism by which transglutaminases modify substrate proteins and their contributions to multiple biological phenomena as well as disease phenotypes, the publication of the present transglutaminase book was planned, to consist of review articles by 17 expert investigators working in this exciting area of research. The book contains detailed information related to several transglutaminases from aspects in chemical and cellular biology, medical sciences, and biotechnology that will also supply starting points for drug discovery. Although many prominent findings have been published in recent years, this type of comprehensive review book has been missing in the scientific literature. This volume will be useful for investigators who either currently work on or will start addressing transglutaminase-related research, and beyond that, for a broad audience in the scientific community. 400 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents a large amount of information related to the heat shock response and heat shock factor (HSF), describes core observations about molecular mechanisms and pathophysiological roles, and provides fundamental concepts on the basis of information from diverse aspects. This adaptive response to high temperature or protein misfolding is a fundamental mechanism to maintain the capacity of protein homeostasis, or proteostasis, and is evolutionally conserved among all living organisms, including bacteria and humans, on the earth. Furthermore, physiological and pathological roles of HSF have been extensively studied in fruit fly, worm, and mouse models. It has been revealed that HSF plays roles in development of the brain, reproductive and sensory organs, and in ageing, inflammation, and circadian rhythm. Analysis of the mechanisms have uncovered that HSF exerts a wide range of effects on gene expression and epigenetic status on the whole genome. Moreover, loss or gain of HSF function is also closely related to protein-misfolding diseases including neurodegenerative diseases, psychiatric diseases, heart diseases, and cancers. Therefore, HSF is now thought to be a promising therapeutic target for treatment of these refractory diseases.For undergraduate students, this is a highly understandable source of information on heart shock response and HSF, covering the basis of HSF biology, the physiological role of HSF, and disease associated with HSF function. This book not only serves as a guide to the heat shock response and HSF for students and young researchers in other fields, but also is a cornerstone for future work in the field related to the heat shock response and HSF. 312 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the '3Rs') and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1-3), DNA Replication; Part 2 (Chapters 4-6), DNA Recombination; Part 3 (Chapters 7-9), DNA Repair; Part 4 (Chapters 10-13), Genome Instability and Mutagenesis; Part 5 (Chapters 14-15), Chromosome Dynamics and Functions; Part 6 (Chapters 16-18), Cell Cycle and Checkpoints; Part 7 (Chapters 19-21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable. 568 pp. Englisch.