springer new york jan 2013 (286 risultati)

Taschenbuch. Condizione: Neu. Neuware -The principal goal of the Handbook of Behavioral Neurobiology is a systematic, critical, and timely exposition of those aspects of neuroscience that have direct and immediate bearing on overt behavior. In this first volume, subtitled 'Sensory Integration,' the subject matter has been subdivided and the authors selected with this particular goal in mind. Although the early chapters (on the phylogeny and ontogeny of sensory systems, and on the common properties of sensory systems) are somewhat too abstract to permit many direct behavioral inferences, the focus on behavior has been maintained there too as closely as is now possible. A behavioral orientation is most obvious in the remaining chapters, which layout for each sensory modality in turn what is now known about structure-behavior relationships. The handbook is primarily intended to serve as a ready reference for two types of readers: first, practicing neuroscientists looking for a concise and authori tative treatment of developments outside of their particular specialities; and second, students of one or another branch of neuroscience who need an overview of the persistent questions and current problems surrounding the relation of the perceptual systems to behavior. The requirements imposed by the decision to address these particular audiences are reflected in the scope and style of the chapters as well as in their content.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 596 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -It is now more than twenty years since a proposal was first mooted to hold an international tunnelling symposium in Britain. At the time of the first symposium, held in London in 1976, the Channel Tunnel pro ject had just been shelved. Last weekend a charity walk was held in the finished tunnel, which will be open for business later in the year. Tunnels have figured prominently, and at times spectacularly, in the development of national and international links and it is hoped that such links gather pace in the future. It is particularly pleasing that Alastair Biggart of Storebrelt has agreed to deliver the twenty-sixth Sir Julius Wernher Memorial Lecture of the Institution of Mining and Metallurgy, entitled 'The changing face of tunnelling', at the start of this event. \* Although almost every edition of the technical journals on tunnelling reports another £1 billion scheme somewhere in the world, it would be unfair of me to suggest that tunnelling is restricted to these prestigious schemes for major transport links. Much of the work that makes mod ern life possible receives hardly a mention outside the technical press and one suspects that society at large applies the 'out of sight, out of mind' attitude even more readily to underground construction than it does to other forms of engineering. Clearly, there is a contiiming need to improve the capacity and performance of our infrastructure, while hav ing a careful regard for the environment.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 848 pp. Englisch.

Buch. Condizione: Neu. Neuware -Continuum Mechanics of Anisotropic Materials(CMAM) presents an entirely new and unique development of material anisotropy in the context of an appropriate selection and organization of continuum mechanics topics. These features will distinguish this continuum mechanics book from other books on this subject. Textbooks on continuum mechanics are widely employed in engineering education, however, none of them deal specifically with anisotropy in materials. For the audience of Biomedical, Chemical and Civil Engineering students, these materials will be dealt with more frequently and greater accuracy in their analysis will be desired. Continuum Mechanics of Anisotropic Materials' author has beena leaderin the field of developing new approaches for the understanding of anisotropic materials.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 440 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -¿¿¿¿¿¿¿Turbulence is a major problem facing modern societies. It makes airline passengers return to their seats and fasten their seatbelts but it also creates drag on the aircraft that causes it to use more fuel and create more pollution. The same applies to cars, ships and the space shuttle. The mathematical theory of turbulence has been an unsolved problems for 500 years and the development of the statistical theory of the Navier-Stokes equations describes turbulent flow has been an open problem. The Kolmogorov-Obukhov Theory of Turbulence develops a statistical theory of turbulence from the stochastic Navier-Stokes equation and the physical theory, that was proposed by Kolmogorov and Obukhov in 1941. The statistical theory of turbulence shows that the noise in developed turbulence is a general form which can be used to present a mathematical model for the stochastic Navier-Stokes equation. The statistical theory of the stochastic Navier-Stokes equation is developed in a pedagogical manner and shown to imply the Kolmogorov-Obukhov statistical theory. This book looks at a new mathematical theory in turbulence which may lead to many new developments in vorticity and Lagrangian turbulence. But even more importantly it may produce a systematic way of improving direct Navier-Stokes simulations and lead to a major jump in the technology both preventing and utilizing turbulence.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 120 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Drinfeld Moduli Schemes and Automorphic Forms: The Theory of Elliptic Modules with Applications is based on the author¿s original work establishing the correspondence between ell-adic rank r Galois representations and automorphic representations of GL(r) over a function field, in the local case, and,in the global case, under a restriction at a single place. It develops Drinfeld¿s theory of elliptic modules, their moduli schemes and covering schemes, the simple trace formula, the fixed point formula, as well as the congruence relations and a 'simple'converse theorem, not yet published anywhere. This version, based on a recent course taught by the author at TheOhio State University, is updated with references to research that has extended and developed the original work. The use of the theory of elliptic modules in the present work makes it accessible to graduate students, and it will serve as a valuable resource to facilitate anentrance to this fascinating area of mathematics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 160 pp. Englisch.

Buch. Condizione: Neu. Neuware -The Theoretical Foundations of Quantum Mechanics addresses fundamental issues that are not discussed in most books on quantum mechanics. This book focuses on analyzing the underlying principles of quantum mechanics and explaining the conceptual and theoretical underpinning of quantum mechanics. In particular, the concepts of quantum indeterminacy, quantum measurement and quantum superposition are analyzed to clarify the concepts that are implicit in the formulation of quantum mechanics.The Schrodinger equation is never solved in the book. Rather, the discussion on the fundamentals of quantum mechanics is treated in a rigorous manner based on the mathematics of quantum mechanics. The new concept of the interplay of empirical and trans-empirical constructs in quantum mechanics is introduced to clarify the foundations of quantum mechanics and to explain the counter-intuitive construction of nature in quantum mechanics.The Theoretical Foundations of Quantum Mechanics is aimed at the advanced undergraduate and assumes introductory knowledge of quantum mechanics. Its objective is to provide a solid foundation for the reader to reach a deeper understanding of the principles of quantum mechanics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -On the Higher-Order Sheffer Orthogonal Polynomial Sequences sheds light on the existence/non-existence of B-Type 1 orthogonal polynomials. This book presents a template for analyzing potential orthogonal polynomial sequences including additional higher-order Sheffer classes. This text not only shows that there are no OPS for the special case the B-Type 1 class, but that there are no orthogonal polynomial sequences for the general B-Type 1 class as well. Moreover, it is quite provocative how the seemingly subtle transition from the B-Type 0 class to the B-Type 1 class leads to a drastically more difficult characterization problem. Despite this issue, a procedure is established that yields a definite answer to our current characterization problem, which can also be extended to various other characterization problems as well.Accessible to undergraduate students in the mathematical sciences and related fields, This book functions as an important reference work regarding the Sheffer sequences. The author takes advantage of Mathematica 7 to display unique detailed code and increase the reader's understanding of the implementation of Mathematica 7 and facilitate further experimentation. In addition, this book provides an excellent example of how packages like Mathematica 7 can be used to derive rigorous mathematical results.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 120 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book presents some recent systems engineering and mathematical tools for health care along with their real-world applications by health care practitioners and engineers. Advanced approaches, tools, and algorithms used in operating room scheduling and patient flow are covered. State-of-the-art results from applications of data mining, business process modeling, and simulation in healthcare, together with optimization methods, form the core of the volume.Systems Analysis Tools for Better Health Care Delivery illustrates the increased need of partnership between engineers and health care professionals. This book will benefit researchers and practitioners in health care delivery institutions, staff members and professionals of specialized hospital units, and lecturers and graduate students in engineering, applied mathematics, business administration and health care.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 188 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Information technology constantly changes and quickly becomes obsolete. The methodology of planning and implementing a health care information system, however, is more constant. Through practical, step-by-step guidelines, the author demonstrates how to establish the strategy and architecture against which vendor and system decisions must be made. Both management and technical perspectives are discussed. Thus, regardless of the technology used, the health care administrator and systems manager learn to implement information systems successfully and to link those systems with business strategy to achieve higher quality and more cost-effective patient care.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 368 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book is an introduction to manifolds at the beginning graduate level. It contains the essential topological ideas that are needed for the further study of manifolds, particularly in the context of differential geometry, algebraic topology, and related fields. Its guiding philosophy is to develop these ideas rigorously but economically, with minimal prerequisites and plenty of geometric intuition.Although this second edition has the same basic structure as the first edition, it has been extensively revised and clarified; not a single page has been left untouched. The major changes include a new introduction to CW complexes (replacing most of the material on simplicial complexes in Chapter 5); expanded treatments of manifolds with boundary, local compactness, group actions, and proper maps; and a new section on paracompactness.This text is designed to be used for an introductory graduate course on the geometry and topology of manifolds. It should be accessible to any student who has completed a solid undergraduate degree in mathematics. The author¿s book Introduction to Smooth Manifolds is meant to act as a sequel to this book.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 452 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This is a short, modern, and motivated introduction to mathematical logic for upper undergraduate and beginning graduate students in mathematics and computer science. Any mathematician who is interested in getting acquainted with logic and would like to learn Gödel¿s incompleteness theorems should find this book particularly useful. The treatment is thoroughly mathematical and prepares students to branch out in several areas of mathematics related to foundations and computability, such as logic, axiomatic set theory, model theory, recursion theory, and computability.In this new edition, many small and large changes have been made throughout the text. The main purpose of this new edition is to provide a healthy first introduction to model theory, which is a very important branch of logic. Topics in the new chapter include ultraproduct of models, elimination of quantifiers, types, applications of types to model theory, and applications to algebra, number theory and geometry. Some proofs, such as the proof of the very important completeness theorem, have been completely rewritten in a more clear and concise manner. The new edition also introduces new topics, such as the notion of elementary class of structures, elementary diagrams, partial elementary maps, homogeneous structures, definability, and many more.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 212 pp. Englisch.

Buch. Condizione: Neu. Neuware -'In this book, Peter Bogetoft - THE expert on the theory and practice of benchmarking - provides an in¿depth yet very accessible and readable explanation of the best way to do benchmarking, starting from the ground up.'Rick AntleWilliam S. Beinecke Professor of Accounting, Yale School of ManagementCFO, Compensation Valuation, Inc.'I highly recommend this well-written and comprehensive book on measuring and managing performance. Dr. Bogetoft summarizes the fundamental mathematical concepts in an elegant, intuitive, and understandable way.'Jon A. ChilingerianProfessor, Brandeis University and INSEAD'Bogetoft gives in his book Performance Benchmarking an excellent introduction to the methodological basis of benchmarking.'Christian ParbølDirector, DONG Energy'This book is the primer on benchmarking for performance management.'Albert BirckBusiness Performance Manager, Maersk Oil'This excellent book provides a non technical introduction for performance management.'Misja MikkersDirector, Dutch Health Care Authority'With this very well written and comprehensive introduction to the many facets of benchmarking in hand, organizations have no excuse for not applying the best and cost effective benchmarking methods in their performance assessments.'Stig P. ChristensenSenior R&D Director, COWISpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 276 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book is the first comprehensive, full-scale treatment of the law, politics and economics with regard to the policies and policy instruments for budget stabilization at the state level. Covering the period from 1946 through 2008 in the United States, it provides details on the methods and results of empirical tests of the effects of budget stabilization instruments on government operations, public service provision, and some other aspects of social and economic life.With the lingering effects of the most recent financial crisis and economic downturn, and the subsequent Tea Party movement advocating smaller government and deficit reduction, this book carries timely and important theoretical as well as practical implications, particularly in regard to the potential for counter-cyclical fiscal policy in mitigating negative impacts during a recession. The first contribution of the book is in public finance theory: it provides insights into the applications of the stabilization function in the context of strong government, thereby refining Keynesianism. The second aspect is in Public Choice: the creation and functioning of budget stabilization funds offer extra evidence to demonstrate that the general public provides input and voice in more than the conventional ways when it comes to policy making, even in an area dominated by strong government. The third aspect is in policy making, exploring the opportunities for refining policy tools in preparation for future downturns.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 376 pp. Englisch.

Buch. Condizione: Neu. Neuware -Why has the clean, limitless energy promised by fusion always seemed just out of reach Search for the Ultimate Energy Source: A History of the U.S. Fusion Energy Program, explains the fundamentals and concepts behind fusion power, and tracesthe development of fusion historically by decade¿covering its history as dictated by US government policies, its major successes, and its prognosis for the future. The reader will gain an understanding of how the development of fusion has been shaped by changing government priorities as well as other hurdles currently facing realization of fusion power.Advance Praise for Search for the Ultimate Energy Source:¿Dr. Dean has been uniquely involved in world fusion research for decades and, in this book, describes the complicated realities like few others possibly could.¿Robert L. Hirsch, a former director of the US fusion program, an Assistant Administrator of the US Energy Research and Development Administration (ERDA); an executive at Exxon, Arco, and the Electric Power Research Institute (EPRI); and lead author of the book The Impending World Energy Mess (Apogee Prime Books, 2009).¿In this book, Dr. Dean provides the many reasons why fusion has progressed more slowly than many had hoped. Budget is usually cited as the culprit, but policy is equally to blame. Facilities have been closed down before their jobs were done¿or in some cases, even started. It seems this situation has become endemic in fusion, and if one thinks about it, in other nationally important Science and Technology initiatives as well.¿William R. Ellis, a former scientist at Los Alamos National Laboratory, Associate Director of Research at the US Naval Research Laboratory, a vice president at Ebasco Services and at Raytheon, and chair of the US ITER Industry Council and the US ITER Industrial Consortium.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Buch. Condizione: Neu. Neuware -Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The volume also covers the management of concomitant cancer risk and screening strategies.A concise, yet comprehensive overview of the current status of the topic, Management of the Patient at High Risk for Breast Cancer serves as a useful resource for physicians and researchers dealing with and interested in patients at high risk for breast cancer.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 200 pp. Englisch.

Buch. Condizione: Neu. Neuware -Thermodynamics is a well-established discipline of physics for properties of matter in thermal equilibrium with the surroundings. Applying to crystals, however, the laws encounter undefined properties of crystal lattice, which therefore need to be determined for a clear and well-defined description of crystalline states. Thermodynamics of Crystalline States explores the roles played by order variables and dynamic lattices in crystals in a wholly new way.The book begins by clarifying basic concepts for stable crystals. Next, binary phase transitions are discussed to study collective motion of order variables, as described mostly as classical phenomena. New to this edition is the examination of magnetic crystals, where magnetic symmetry is essential for magnetic phase transitions. The multi-electron system is also discussed theoretically, as a quantum-mechanical example, for superconductivity in metallic crystals. Throughout the book, the role played by the lattice is emphasized and studied in-depth.Thermodynamics of Crystalline States is an introductory treatise and textbook on mesoscopic phenomena in solid states, constituting a basic subject in condensed matter physics. While this book serves as a guide for advanced students in physics and material science, it can also be useful as a reference for all professionals in related fields.Minoru Fujimoto is author of Physics of Classical Electromagnetism (Springer, 2007) and The Physics of Structural Phase Transitions (Springer, 2005).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Buch. Condizione: Neu. Neuware -This thesis presents a significant contribution to decentralized resource allocation problems with strategic agents. The study focused on three classes of problems arising in communication networks. (C1). Unicast service provisioning in wired networks. (C2). Multi-rate multicast service provisioning in wired networks. (C3). Power allocation and spectrum sharing in multi-user multi-channel wireless communication systems. Problems in (C1) are market problems; problems in (C2) are a combination of markets and public goods; problems in (C3) are public goods. Dr. Kakhbod developed game forms/mechanisms for unicast and multi-rate multicast service provisioning that possess specific properties. First, the allocations corresponding to all Nash equilibria (NE) of the games induced by the mechanisms are optimal solutions of the corresponding centralized allocation problems, where the objective is the maximization of the sum of the agents' utilities. Second, the strategic agents voluntarily participate in the allocation process. Third, the budget is balanced at the allocations corresponding to all NE of the game induced by the mechanism as well as at all other feasible allocations. For the power allocation and spectrum sharing problem, he developed a game form that possesses the second and third properties as detailed above along with a fourth property: the allocations corresponding to all NE of the game induced by the mechanism are Pareto optimal. The thesis contributes to the state of the art of mechanism design theory. In particular, designing efficient mechanisms for the class of problems that are a combination of markets and public goods, for the first time, have been addressed in this thesis. The exposition, although highly rigorous and technical, is elegant and insightful which makes this thesis work easily accessible to those just entering this field and will also be much appreciated by experts in the field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 108 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book was written to provide resource materials for teachers to use in their introductory or intermediate statistics class. The chapter content is ordered along the lines of many popular statistics books so it should be easy to supplement the content and exercises with class lecture materials.The book contains R script programs to demonstrate important topics and concepts covered in a statistics course, including probability, random sampling, population distribution types, role of the Central Limit Theorem, creation of sampling distributions for statistics, and more. The chapters contain T/F quizzes to test basic knowledge of the topics covered. In addition, the book chapters contain numerous exercises with answers or solutions to the exercises provided. The chapter exercises reinforce an understanding of the statistical concepts presented in the chapters. An instructor can select any of the supplemental materials to enhance lectures and/or provide additional coverage of concepts and topics in their statistics book.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume explores the cross-linkages between the kinetic processes and macroscopic phenomena in the solar atmosphere, which are at the heart of our current understanding of the heating of the closed and open corona and the acceleration of the solar wind. The focus lies on novel data, on theoretical models that have observable consequences through remote sensing, and on near-solar and inner-heliosphere observations, such as anticipated by the upcoming Solar Orbiter and Solar Probe missions, which are currently developed by the international community.This volume is aimed at students and researchers active in solar physics and space science.Previously published in Space Science Reviews journal, Vol. 172, Nos. 1-4, 2012.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 416 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -It is now over 30 years since the idea of ion-conducting pores burst on the elec trophysiological scene, 15 years since these were generalIy realized to be mem brane-spanning proteins, and 10 years since the first observations of single ion channels from higher organisms were made. During the past 5 years, several integral membrane channel proteins have been purified in a functionalIy competent state: the nicotinic acetylcholine receptor, the Na + channel, mitochondrial 'VDAC,' and a variety of porins. The stage is thus set to attack ion channels in the same ways that biochemists have been attacking enzymes for decades: isolation folIowed by functional analysis in as simple a system as possible, with a view towards understanding the molecular mechanisms ofthe protein's behavior and how this is related to the underlying molecular structure. This is always a daunting task, alI the more so with ion channels because of our still primitive and scanty understanding of channel structures and because of the difficulty in iso lating functionally active channel proteins. In this volume, which can be considered a biochemically slanted companion to Sakmann and Neher's Single-Channel Recording, I have tried to present a view of the current landscape of ion-channel reconstitution. These chapters illustrate not only the different approaches and techniques of the major practitioners of ion channel reconstitution but, as importantly, the varied motivations for doing this kind of work.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 600 pp. Englisch.

Buch. Condizione: Neu. Neuware -The goal of this book is to show how to build and manage a food safety department that is tasked with ensuring food safety within a food retail business. The experiences of the author as the head of Food and Product Safety at Chick-fil-A will be used as the model. Specifically, the book will discuss the specific components of a food safety program, the tactics needed to establish these components (forming the majority of the chapters), how to measure the success of each component, and how to influence the organization to ensure resources to support the program. The book will also focus on how to choose and work with the appropriate partners, validate the value to the business, and initiate the new component throughout the organization, including how to sustain the component within the program.Five features of this book that make it distinctive are: Most current ¿How tö book on leading a food safety department from the perspective of a respected national brandProvides the proper organization and methods to manage the work necessary to ensure food safety within the organizationProvides the means to utilize risk-based decisions linked to business practices that accommodate a business analysis modelDemonstrates step-by-step examples that can be used for continuous improvement in sustaining food safety responsibilitiesProvides examples on how to gain influence and obtain resources to support food safety responsibilitiesSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 144 pp. Englisch.

Buch. Condizione: Neu. Neuware -Advances in hardware technology have lead to an ability to collect data with the use of a variety of sensor technologies. In particular sensor notes have become cheaper and more efficient, and have even been integrated into day-to-day devices of use, such as mobile phones.This has lead to a much larger scale of applicability and mining of sensor data sets. The human-centric aspect of sensor data hascreated tremendous opportunities in integrating social aspects of sensor data collection into the mining process.Managing and Mining Sensor Data is a contributed volume by prominent leaders in this field, targeting advanced-level students in computer science as a secondary text book or reference. Practitioners and researchers working in this field will also find this book useful.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 548 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume summarizes the state-of-the-art in the fast growing research area of modeling the influence of information-driven human behavior on the spread and control of infectious diseases. In particular, it features the two main and inter-related ¿core¿ topics: behavioral changes in response to global threats, for example, pandemic influenza, and the pseudo-rational opposition to vaccines.In order to make realistic predictions, modelers need to go beyond classical mathematical epidemiology to take these dynamic effects into account.With contributions from experts in this field, the book fills a void in the literature. It goes beyond classical texts, yet preserves the rationale of many of them by sticking to the underlying biology without compromising on scientific rigor. Epidemiologists, theoretical biologists, biophysicists, applied mathematicians, and PhD students will benefit from this book. However, it is also written for Public Health professionals interested in understanding models, and to advanced undergraduate students, since it only requires a working knowledge of mathematical epidemiology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

Buch. Condizione: Neu. Neuware -Psychology has focused more on personalities in poverty -- pathologizing -- than on contexts for poverty reduction (Pick & Sirkin, 2010). As a result, the discipline has inadvertently sequestered and isolated itself, and its potential contribution, from poverty reduction initiatives - globally and locally. In recent years, there have been major developments in both the scope and depth of psychological research on global development issues. Some of the key developments include significant advances in understanding of what motivates teachers in schools, on designing community interventions to promote health, and on managing the development of human ¿capacity¿ in aid and development projects. The Psychology of Poverty Reduction is poised to capture such advances in the understanding of ¿what works¿ - and what does not.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This Companion Textbook supplements the ActivEpi CD-ROM, sold separately. The ActivEpi CD-ROM provides a multimedia presentation of concepts, commonly taught in an introductory epidemiology course. ActivEpi mixes a full array of media to motivate, explain, visualize and apply epidemiological concepts. Virtually all of the material on the ActivEpi CD-ROM is included in the Companion Textbook. Because individuals differ in their learning skills, the ActivEpi CD-ROM and the ActivEpi Companion Textbook offer readers different but related options on how to learn epidemiology. The Textbook can be used as a hardcopy reference of the textual materials contained on the CD-ROM, as a resource for the practice exercises, as a general reference, or even a self-contained textbook. ActivEpi includes 15 lessons and over 50 hours of content via more than 250 launchable activities and homework exercises. It can be used in a variety of teaching formats: distance learning, self-paced learning, on-campus courses, and short courses. For the latest additions to ActivEpi, visit David Kleinbaum's website.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 564 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel's first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders.The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Condizione: Neu. Neuware -The space between the stars contains a large diversity of objects in which physical processes occur that are fundamental to the structure and evolution of galaxies. This book offers the reader a basic knowledge of these processes and presents simple numeric estimates of the main quantities relevant to the interstellar medium. The main objects that constitute the interstellar space are described, but the emphasis of the book lies in the physical processes occurring in these objects, which may also occur in other astrophysical environments. The book is directed tor graduate as well as advanced undergraduate students of physics and astrophysics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 276 pp. Englisch.

Buch. Condizione: Neu. Neuware -Recent research in health decision making has shown that many patients, even those with a college education, have difficulties grasping a host of numerical concepts, including percentages and probabilities. Yet, basic numeracy and graph literacy are essential for understanding information relevant to making decisions about health, such as the incidence and prevalence of different diseases, risk reductions from medical screenings and treatments, and risk increases from side effects of treatments and unhealthy behaviors. Patients who have problems understanding such numerical concepts are often prone to errors in risk perception and medical choices. Importantly, informed medical decision making, heavily reinforced these days by the legal requirement for informed consent, depends critically on communication of quantitative medical information. Meeting the challenge of effectively communicating medical information to patients with different levels of numeracy and graph literacy has become more important than ever.Transparent Communication of Health Risks describes a series of cross-cultural studies investigating how people in countries with different medical and educational systems understand numerical and graphical information, what they know about existing medical treatments and screenings, which presentation formats help them better understand the relevant information, and how they use the data to make medical decisions. Focusing on the careful measurement of necessary knowledge and skills, the book also includes validated numeracy and graph literacy scales in English, Spanish, and German. Some of the topics covered in the book are:numeracy and graph literacy for health;measuring risk comprehension in educated samples;communicating information about medical treatment and screening;reducing the effect of framed messages about health;the effect of individual differences on shareddecision making; andtransparent health information in the media.Transparent Communication of Health Risks emphasizes the importance and value of working toward the development of tailored risk communication interventions and clarifies the tasks ahead for health psychologists, public health professionals, pharmaceutical and medical education companies, medical physicists, and nurses.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 284 pp. Englisch.

Buch. Condizione: Neu. Neuware -Molecular Pathology of Neoplastic Gastrointestinal Diseases reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect thegastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on:the molecular basis of the individual diseasemolecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapiesrecommended guidelines for clinical application of molecular tests are included whenever availablemolecular testing for hereditary predisposition or disease riskanimal models and cell culture models of diseaseSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Buch. Condizione: Neu. Neuware -Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of multiple myeloma. This book will give a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 136 pp. Englisch.