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Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441955208ISBN 13: 9781441955203
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Medical Wisdom and Doctoring aims to fill a need in the current medical literature for a resource that presents some of the classic wisdom of medicine, presented in a manner that can help today's physicians achieve their full potential. This book details the lessons every physician should have learned in medical school but often didn't, as well as classic insights and examples from current clinical literature, medical history, and anecdotes from the author's long and distinguished career in medicine. Medical Wisdom and Doctoring: the Art of 21st Century Practice presents lessons a physician may otherwise need to learn from experience or error, and is sure to become a must-have for medical students, residents and young practitioners. 384 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441910581ISBN 13: 9781441910585
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This innovative book focuses on HDL and its relationships to triglyceride-rich particles. As new therapies for HDL raising become available, a comprehensive understanding the role of HDL in Coronary Heart Disease is of great importance. This book is an excellent resource for educating physicians and scientists about dyslipidemia and HDL metabolism, including many exogenous substances which interact with and influence HDL. Readers will benefit from the unique visual exposition and the insights of international experts. 220 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441914757ISBN 13: 9781441914750
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book comprises empirical tests of the theoretical implications of collective action theory specifically with regard to mobilization. It is based on the author's European Protest and Coercion Data, which won the Comparative Politics Section of American Political Science Association award for the best data set in 2007. The dataare supplemented by historical investigations as well as other research. The volume is divided into six chapters. The introduction covers the theory of collective action in its many manifestations as well as the process of drawing out theoretical implications. The second chapter goes to the core of the mobilization issues, especially with regard to the role of leadership, which is inextricably linked to mobilization. The third chapter applies the concept of adaptation to the development of more productive tactics that promote mobilization in support of a public good and minimize the possibility of repression. In chapter four, five spatial hypotheses based on rationality and formal theories are developed and the role of time in protests is addressed. The fifth chapter focuses on the fundamental problems of terror with evidence from the Basque region of Spain and France from Ireland against the Provisional Irish Revolutionary Army in Northern Ireland. The final chapter surveys the empirical evidence and summarizes the support of collective action theory. Testing collective action theory implications with empirical evidence will appeal to political scientists, sociologists, economists and researchers concerned with mobilization. 132 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441956948ISBN 13: 9781441956941
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In their 1909 publication Théorie des corps déformables, Eugène and François Cosserat made a historic contribution to materials science by establishing the fundamental principles of the mechanics of generalized continua. The chapters collected in this volume showcase the many areas of continuum mechanics that grew out of the foundational work of the Cosserat brothers.The included contributions provide a detailed survey of the most recent theoretical developments in the field of generalized continuum mechanics and can serve as a useful reference for graduate students and researchers in mechanical engineering, materials science, applied physics and applied mathematics. 360 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441958738ISBN 13: 9781441958730
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mathematical modelling and computer simulation have proved tremendously successful in engineering. One of the greatest challenges for mechanists is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, biomedical sciences, and medicine. The proposed workshop will provide an opportunity for computational biomechanics specialists to present and exchange opinions on the opportunities of applying their techniques to computer-integrated medicine. For example, continuum mechanics models provide a rational basis for analysing biomedical images by constraining the solution to biologically reasonable motions and processes. Biomechanical modelling can also provide clinically important information about the physical status of the underlying biology, integrating information across molecular, tissue, organ, and organism scales. The main goal of this workshop is to showcase the clinical and scientific utility of computational biomechanics in computer-integrated medicine. 168 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441911596ISBN 13: 9781441911599
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Pancreatic cancer is the fourth leading cause of cancer death in the United States. Every year, about 33,700 people in the United States will be diagnosed with pancreatic cancer and over 32,000 patients will die from the disease. The median survival of patients with advanced pancreatic cancer is about 6-months. This dismal picture of pancreatic cancer is mainly due to the lack of early diagnosis and effective treatment for patients with advanced disease. To increase the survival rate of pancreatic cancer patients, better tumor markers for diagnosis and new molecular targets for drug development are desperately needed. A lot of effort has been made in searching for pancreatic cancer-causing genes or genes associated with progression of malignant behavior in pancreatic cancer. As a result, alterations in the expression of several cancer-related genes have been identified in pancreatic tumors. The identification and characterization of these cancer-related genes have significantly increased our understanding of pancreatic cancer development, but unfortunately the treatment of pancreatic cancer has not advanced as much in the past 20 years.Over the past decade, tremendous advances have been made in the field of cancer drug discovery, particularly, in the area of molecular and genetic models and technologies. Many of those advanced models and technologies have been applied to the drug discovery processes for pancreatic cancer. In this book, a team of experts will describe the latest development in the application of these models and technologies in pancreatic cancer. The authors include basic researchers as well as clinicians who work in the front-line of the war against pancreatic cancer and have the first-hand experience on these cutting-edge tools and techniques. The book can be divided into two general areas: 1) model systems and 2) genomics and proteomics tools. In recent years there have been a lot of advances in the model systems for pancreatic cancer, including the further characterization of normal and cancerous pancreatic cell lines, the establishment of transgenic mouse models that recapitulate the initiation and progression of human pancreatic cancer, the development of a new xenograft model system for the evaluation of novel agents, and the establishment of a zebrafish pancreatic cancer model. The first four chapters of the book will be devoted to these models. The advances in genomics and proteomics research have made a major impact in cancer drug discovery. A number of these -omics-based tools and techniques have been applied in the pancreatic cancer drug discovery. Chapters 5-9 of the book will discuss techniques for genome-wide examination of gene expression, copy number, methylation, function and regulation. Chapters 10-11 will discuss in situ techniques for studying chromosomal and gene copy number abnormalities as well protein expression changes in cancer samples. Chapters 12-14 will focus on techniques for global examination of protein expression levels in biospecimens obtained from pancreatic cancer patients. Cancer drug discovery has become more and more target-centric. 320 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441915257ISBN 13: 9781441915252
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A Public Health Perspective of Women's Mental HealthEdited by Bruce Lubotsky Levin and Marion Ann BeckerAs many as one-half of all women in the U.S. will experience some form of mental illness in their lives-an especially distressing fact when health care budgets are in flux, adding to existing disparities and unmet health needs.Written from a unique multidisciplinary framework, A Public Health Perspective of Women's Mental Health addresses today's most pressing mental health challenges: effective treatment, efficient prevention, equal access, improved service delivery, and stronger public policy. Eminent clinicians, researchers, academicians, and advocates examine the effects of mental illness on women's lives and discuss the scope of clinical and service delivery issues affecting women, focusing on these major areas:Epidemiology of mental disorders in girls, female adolescents, adult women, and older women.Selected disorders of particular concern to women, including depression and postpartum depression, eating disorders, menopause, chemical dependence, and HIV/AIDS.Mental health needs of women in the workplace, rural areas, and prisons.Racial and ethnic disparities and their impact on service delivery.Parenting and recovery issues in mothers with mental illness.Women's mental health services in an era of evidence-based medicine.Improving women's health in today's technological climate. A Public Health Perspective of Women's Mental Health is a resource of immediate importance to professionals and graduate students in the public health, health administration, health disparities, social work, behavioral health, and health services research fields, as well as nursing, community/health psychology and community/public psychiatry. 432 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441917691ISBN 13: 9781441917690
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cancer is fundamentally a disease of abnormal cell proliferation: Cancer cells multiply when and where they should not. This proliferation entails escape from normal bounds imposed by the tissue environment, the internal biology of the cell (DNA damage, chromosomal imbalances, disorganized mitotic spindles), and the proliferative history of the cell (normal generational times). Some of the key oncogenic events in cancer directly perturb proteins that regulate progression through the cell division cycle, others alter cell cycle progression indirectly, through effects on signaling pathway that impinge on the cell cycle. This biology is fundamentally important in cancer therapy. Many of the workhorse treatments for cancer rely on killing proliferating cells. Furthermore, there is growing recognition that stem cell-transit amplifying cell hierarchies may persist or be generated during tumorigenesis, generating important functional heterogeneity in cell cycle control among tumor cells, with far-reaching scientific and clinical implications. This volume outlines major cell cycle perturbations that drive tumorigenesis and considers the prospects for using such knowledge in cancer therapy. 216 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 0387896856ISBN 13: 9780387896854
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since 1985, scientists have been documenting a hypoxic zone in the Gulf of Mexico each year. The hypoxic zone, an area of low dissolved oxygen that cannot s- port marine life, generally manifests itself in the spring. Since marine species either die or ee the hypoxic zone, the spread of hypoxia reduces the available habitat for marine species, which are important for the ecosystem as well as commercial and recreational shing in the Gulf. Since 2001, the hypoxic zone has averaged 2 1 16,500 km during its peak summer months , an area slightly larger than the state 2 2 of Connecticut, and ranged from a low of 8,500 km to a high of 22,000 km . To address the hypoxia problem, the Mississippi River/Gulf of Mexico Watershed Nutrient Task Force (or Task Force) was formed to bring together represen- tives from federal agencies, states, and tribes to consider options for responding to hypoxia. The Task Force asked the White House Of ce of Science and Technology Policy to conduct a scienti c assessment of the causes and consequences of Gulf hypoxia through its Committee on Environment and Natural Resources (CENR). 336 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441956913ISBN 13: 9781441956910
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Breathing is performed by the rhythmic contraction of respiratory muscles. It ma- tains homeostasis of the organism by taking in the oxygen necessary to live and work and by controlling the level of CO within the organism. At first glance, breathing 2 seems simple; however, it is produced by a complex system in the brain with various afferents and efferents. The control of breathing is of the utmost importance in s- taining life, and although more than 150 years have passed since research on brea- ing control was first begun, many unsolved mysteries still remain. Breathing is like watching the tides at a beach that are created by the vast, complex open sea. The first Oxford Conference on Modeling and Control of Breathing was held 30 years ago in September of 1978 at the University Laboratory of Physiology in Oxford, England. During this first conference, the participants engaged in a hot d- cussion on the problem of whether breathing rhythm was produced by pacemaker cells or a neural network. This was before the discovery of the Bötinger complex in the medulla, and at the time, central chemoreceptive areas were still the focus of research. This conference was an especially unforgettable moment in the dawning of the new age of respiratory research. It has since been held every 3 years in various countries around the globe and is widely appreciated as the best respiratory meeting in the world. 408 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441914714ISBN 13: 9781441914712
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The purpose of this book is to provide a current perspective on the epidemiology head and neck cancer. Cancers of the oral cavity, pharynx, and larynx comprise an important group of tumors with diverse international patterns of incidence and mortality, established risk factors, suggested association with a virus, and potential genetic susceptibility determinants. These tumors offer a unique insight into mechanisms of cancer initiation and progression and gene-exposure interaction. 220 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441915400ISBN 13: 9781441915405
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Genetics and Genomics of Populus provides an indepth description of the genetic and genomic tools and approaches for Populus, examines the biology that has been elucidated using genomics, and looks to the future of this unique model plant. This volume is designed to serve both experienced Populus researchers and newcomers to the field. Contributors to the volume are a blend of researchers, some who have spent most of their research career on Populus and others that have moved to Populus from other model systems. Research on Populus forms a useful complement to research on Arabidopsis. In fact, many plant species found in nature are - in terms of the life history and genetics - more similar to Populus than to Arabidopsis. Thus, the genetic and genomic strategies and tools developed by the Populus community, and showcased in this volume, will hopefully provide inspiration for researchers working in other, less well developed, systems. 400 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441908285ISBN 13: 9781441908285
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 504 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441959785ISBN 13: 9781441959782
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The microbial world has given us many surprises including microbes that grow under extremely harsh conditions (122C at 40 MPa), novel metabolisms such as the uranium and perchlorate reduction, and novel chemicals that can be used to control diseases. We continually face new and difficult problems such as the need to transition to more carbon-neutral energy sources and to find eco-friendly chemicals and to find new drugs to treat disease. Will it be possible to tap into the seemingly limitless potential of microbial activity to solve our current and future problems The answer to this question is probably yes. We are already looking to the microbial world to provide new energy sources, green chemicals to replace those made from petroleum, and new drugs to fight disease. To help us along these paths, we are deciphering how microorganisms interact with each other. We know that microbial populations interact and communicate with each other. The language that microbes use is chemical where small molecules are exchanged among different microbial cells. Sometimes, these chemicals suppress activities of competitors and could be used as antibiotics or may have other therapeutic uses. Other times, the chemicals stimulate complex responses in microbial populations such as fruiting body or biofilm formation. By understanding the conversation that microbes are having among themselves, e. g. 360 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441916717ISBN 13: 9781441916716
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis. 432 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 144191398XISBN 13: 9781441913982
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -TheInternationalSymposiumonRetinalDegenerationhasbeenheldinconjunction withthebiennialInternationalCongressofEyeResearch(ICER)since1984. These RDSymposiahaveallowedbasicandclinicianscientistsfromaroundtheworldto conveneandpresenttheirnewresearch ndings. Theyhavebeenorganizedtoallow suf cienttimefordiscussionsandone-on-oneinteractionsinarelaxedatmosp here, whereinternationalfriendshipsandcollaborationscanbefostered. The XIII International Symposium on Retinal Degeneration (also known as RD2008) was held from September 18 23, 2008 at the Hong Zhu Shan Hotel at thefootofEmeiMountainintheSichuanProvinceofChina,nearChengdu. The meeting brought together 152 basic and clinician scientists, retinal specialists in ophthalmology,andtraineesinthe eldfromallpartsoftheworld. Inthecourse ofthemeeting,42platformand88posterpresentationsweregiven,andamajority ofthesearepresentedinthisproceedingsvolume. Newdiscoveriesandstateofthe art ndingsfrommostresearchareasinthe eldofretinaldegenerationswerep- sented. TheRD2008meetingwashighlightedbythreespeciallectures. The rstwas givenby Glen Prusky,PhD,WeillCornellMedicalCollegeofCornellUniversity, New York City, NY. Dr. Prusky discussed the measures of vision in rodents as a tool for evaluating the treatment of retinal degenerative diseases. The second was given by Kang Zhang, MD, PhD, on the molecular genetics of Stargardt s Disease. Dr. Zhang s undergraduate degree in biochemistry is from West China University in Chengdu, and he currently is at the Shiley Eye Center, University ofCaliforniaatSanDiego,SanDiego,CA. Thethirdplenarylecturewasgivenby Peter Campochiaro,MD,oftheWilmerEyeInstitute,JohnsHopkinsUniversity, Baltimore, MD. Dr. Campochiaro discussed the role of oxidant stress in macular degeneration. This Symposium would not have been possible without the support of our colleagues at the Sichuan People s Provincial Hospital and the Department of Ophthalmology of West China Hospital, Sichuan University. Fan Ying Chuan, MD,ViceChairman,SichuanOphthalmologySociety,DirectorofOphthalmology Department,SichuanAcademyofMedicalScience&SichuanProvincialPeople s Hospitaland Chen Xiao Ming,MD,Chairman,SichuanOphthalmologySociety, Director of West China Eye Center, West China Hospital, Sichuan University, gave tirelessly to our effort from the beginning. We are especially grateful to the ix x Preface administration of the Sichuan People s Provincial Hospital, which provided the nancialguaranteesnecessarytosecurethemeetingvenue. Theassistanceof Chen Hui (Robert), MD, of the SPPH throughout the planning and the meeting itself were of enormous help to us. 764 pp. Englisch.
Editore: Springer New York Mrz 2010, 2010
ISBN 10: 1441914161ISBN 13: 9781441914163
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -At present, the marketplace for professionals, researchers, and graduate students in solid-state physics and materials science lacks a book that presents a comprehensive discussion of ferroelectrics and related materials in a form that is suitable for experimentalists and engineers. This book proposes to present a wide coverage of domain-related issues concerning these materials. This coverage includes selected theoretical topics (which are covered in the existing literature) in addition to a plethora of experimental data which occupies over half of the book.The book presents experimental findings and theoretical understanding of ferroic (non-magnetic) domains developed during the past 60 years. It addresses the situation by looking specifically at bulk crystals and thin films, with a particular focus on recently-developed microelectronic applications and methods for observations of domains with techniques such as scanning force microscopy, polarized light microscopy, scanning optical microscopy, electron microscopy, and surface decorating techniques.'Domains in Ferroic Crystals and Thin Films' covers a large area of material properties and effects connected with static and dynamic properties of domains, which are extremely relevant to materials referred to as ferroics. In other textbooks on solid state physics, one large group of ferroics is customarily covered: those in which magnetic properties play a dominant role. Numerous books are specifically devoted to magnetic ferroics and cover a wide spectrum of magnetic domain phenomena. In contrast, 'Domains in Ferroic Crystals and Thin Films' concentrates on domain-related phenomena in nonmagnetic ferroics. These materials are still inadequately represented in solid state physics textbooks and monographs. 840 pp. Englisch.