Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493924060 ISBN 13: 9781493924066
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 53,49
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Veteran clinicians offer a unique framework for understanding the psychological origins of behaviors typical of Alzheimer's and other dementias, and for providing appropriate care for patients as they decline. Guidelines are rooted in the theory of retrogenesis in dementia--that those with the condition regress in stages toward infancy--as well as knowledge of associated brain damage. The objective is to meet patients where they are developmentally to best be able to address the tasks of their daily lives, from eating and toileting to preventing falls and wandering. This accessible information gives readers a platform for creating strategies that are respectful, sensitive, and tailored to individual needs, thus avoiding problems that result when care is ineffective or counterproductive. Featured in the coverage: Abilities and disabilities during the different stages of Alzheimer's disease.Strategies for keeping the patient's finances safe.Pain in those with dementia, and why it is frequently ignored.'Help! I've lost my mother and can't find her!'Sexuality and intimacy in persons with dementia.Instructive vignettes of successful caring interventions. Given the projected numbers of individuals expected to develop dementing conditions, Care Giving for Alzheimer's Disease will find immediate interest among clinical psychologists, health psychologists, psychiatrists, social workers, and primary care physicians. 144 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1461489237 ISBN 13: 9781461489238
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 53,49
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book explores the unique relationships between professional baseball teams and the unique ways professional baseball leagues are organized in North America with a primary focus on how proximity can and does impact consumer demand. Perhaps more than any other matter that arises in the business of baseball, proximity to other professional baseball teams is a concern that has uniquely shaped professional baseball leagues in North America. It is this particular component in how professional baseball leagues are organized that suggests building a proximity-based approach to studying the economics of minor league baseball. This book opens up new ways to study minor league baseball, specifically, and sports leagues more generally. So even as advanced technology has eliminated some of the need for fans to be in close proximity to the teams they love to follow, there is still a need to understand more completely how proximity matters can impact the way professional baseball leagues are structured and how that structure can ultimately impact the quality of the games that entertain sports fans everywhere. This book will be of interest to both sports economists and practitioners. 144 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493922432 ISBN 13: 9781493922437
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 53,49
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This SpringerBrief details the MESSENGER Mission, the findings of which present challenges to widely held conventional views and remaining mysteries surrounding the planet. The work answers the question of why Mercury is so dense, and the implications from geochemical data on its planetary formation. It summarizes imaging and compositional data from the terrestrial planet surface processes and explains the geologic history of Mercury. It also discusses the lack of southern hemisphere coverage. Our understanding of the planet Mercury has been in a transitional phase over the decades since Mariner 10. The influx of new data from the NASA MESSENGER Mission since it was inserted into the orbit of Mercury in March of 2011 has greatly accelerated that shift. The combined compositional data of relatively high volatiles (S, K), relatively low refractories (Al, Ca), and low crustal iron, combined with an active, partially molten iron rich core, has major implications for Mercury and Solar System formation. From a scientist at NASA Goddard Space Flight Center, this presents a comprehensive overview of the discoveries from the ten-year MESSENGER mission. 108 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493922815 ISBN 13: 9781493922819
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 53,49
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents the details of the BONUS algorithm and its real world applications in areas like sensor placement in large scale drinking water networks, sensor placement in advanced power systems, water management in power systems, and capacity expansion of energy systems. A generalized method for stochastic nonlinear programming based on a sampling based approach for uncertainty analysis and statistical reweighting to obtain probability information is demonstrated in this book. Stochastic optimization problems are difficult to solve since they involve dealing with optimization and uncertainty loops. There are two fundamental approaches used to solve such problems. The first being the decomposition techniques and the second method identifies problem specific structures and transforms the problem into a deterministic nonlinear programming problem. These techniques have significant limitations on either the objective function type or the underlying distributions for the uncertain variables. Moreover, these methods assume that there are a small number of scenarios to be evaluated for calculation of the probabilistic objective function and constraints. This book begins to tackle these issues by describing a generalized method for stochastic nonlinear programming problems. This title is best suited for practitioners, researchers and students in engineering, operations research, and management science who desire a complete understanding of the BONUS algorithm and its applications to the real world. 164 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493924885 ISBN 13: 9781493924882
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 58,84
Quantità: 1 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book helps in Achieving food safety success which requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of the human dimensions of food safety. In the field of food safety today, much is documented about specific microbes, time/temperature processes, post-process contamination, and HACCP-things often called the hard sciences. There is not much published or discussed related to human behavior-often referred to as the 'soft stuff.' However, looking at foodborne disease trends over the past few decades and published regulatory out-of-compliance rates of food safety risk factors, it's clear that the soft stuff is still the hard stuff. Despite the fact that thousands of employees have been trained in food safety around the world, millions have been spent globally on food safety research, and countless inspections and tests have been performed at home and abroad, food safety remains a significant public health challenge. Why is that Because to improve food safety, we must realize that it's more than just food science; it's the behavioral sciences, too. In fact, simply put, food safety equals behavior. This is the fundamental principle of this book. If you are trying to improve the food safety performance of a retail or food service establishment, an organization with thousands of employees, or a local community, what you are really trying to do is change people's behavior. The ability to influence human behavior is well documented in the behavioral and social sciences. However, significant contributions to the scientific literature in the field of food safety are noticeably absent. This book will help advance the science by being the first significant collection of 50 proven behavioral science techniques, and be the first to show how these techniques can be applied to enhance employee compliance with desired food safety behaviors and make food safety the socialnorm in any organization. 132 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1489996672 ISBN 13: 9781489996671
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 96,29
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Linear mixed-effects models (LMMs) are an important class of statistical models that can be used to analyze correlated data. Such data are encountered in a variety of fields including biostatistics, public health, psychometrics, educational measurement, and sociology. This book aims to support a wide range of uses for the models by applied researchers in those and other fields by providing state-of-the-art descriptions of the implementation of LMMs in R. To help readers to get familiar with the features of the models and the details of carrying them out in R, the book includes a review of the most important theoretical concepts of the models. The presentation connects theory, software and applications. It is built up incrementally, starting with a summary of the concepts underlying simpler classes of linear models like the classical regression model, and carrying them forward to LMMs. A similar step-by-step approach is used to describe the R tools for LMMs. All the classes of linearmodels presented in the book are illustrated using real-life data. The book also introduces several novel R tools for LMMs, including new class of variance-covariance structure for random-effects, methods for influence diagnostics and for power calculations. They are included into an R package that should assist the readers in applying these and other methods presented in this text. 576 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1489993665 ISBN 13: 9781489993663
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Mobile Speech and Advanced Natural Language Solutions' presents the discussion of the most recent advances in intelligent human-computer interaction, including fascinating new study findings on talk-in-interaction, which is the province of conversation analysis, a subfield in sociology/sociolinguistics, a new and emerging area in natural language understanding. Editors Amy Neustein and Judith A. Markowitz have recruited a talented group of contributors to introduce the next generation natural language technologies for practical speech processing applications that serve the consumer's need for well-functioning natural language-driven personal assistants and other mobile devices, while also addressing business' need for better functioning IVR-driven call centers that yield a more satisfying experience for the caller. This anthology is aimed at two distinct audiences: one consisting of speech engineers and system developers; the other comprised of linguists and cognitive scientists. The text builds on the experience and knowledge of each of these audiences by exposing them to the work of the other. 384 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1489989277 ISBN 13: 9781489989277
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book discusses various aspects, challenges, and solutions for developing systems-of-systems for situation awareness, using applications in the domain of maritime safety and security. Topics include advanced, multi-objective visualization methods for situation awareness, stochastic outlier selection, rule-based anomaly detection, an ontology-based event model for semantic reasoning, new methods for semi-automatic generation of adapters bridging communication gaps, security policies for systems-of-systems, trust assessment, and methods to deal with the dynamics of systems-of-systems in run-time monitoring, testing, and diagnosis. Architectural considerations for designing information-centric systems-of-systems such as situation awareness systems, and an integrated demonstrator implementing many of the investigated aspects, complete the book. 284 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493925369 ISBN 13: 9781493925360
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3',5'-monophosphate (cAMP) compartmentalization, that probe relevant protein-protein interactions, that increase the spatial and temporal resolution of cAMP signal detection, and that can facilitate integration of the mounting complexity of the information that is becoming available on this signaling system. cAMP, the prototypical intracellular second messenger, regulates a large variety of cellular functions and biological processes, including gene transcription, cell metabolism, proliferation, development, as well as more specialized functions depending on the cell type, so the realization of its extremely complex spatial organization and local regulation is providing novel mechanistic insight into cell physiology and is producing a novel framework for the identification of disease mechanisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Practical and authoritative, cAMP Signaling: Methods and Protocols serves as a vital resource for researchers working in this expanding, complex field. 232 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 149392625X ISBN 13: 9781493926251
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Parasomnias are phenomena that occur exclusively during sleep or are exacerbated during sleep/wake transition. These disorders are known to contribute towards impaired quality of life, disturbed and non-restorative sleep, risk for injuries to self and others and often associated with other medical, neurological and psychiatric disorders. Advances in sleep medicine have revealed a high prevalence of parasomnias across all ages. With the growing interest for diagnosing and management of parasomnias in sleep medicine, a practical guide to parasomnias is greatly needed.Parasomnias provides a comprehensive review of epidemiology, pathophysiology, clinical characteristics, diagnostic evaluation and treatment of parasomnias across the patient's life span. Written by experts, each chapter integrates the latest research and clinical data. In addition, several chapters address medico-legal and forensic aspects of parasomnias.Clinicians and researchers with an interest in sleep medicine will find Parasomnias to not only be an important contribution to the literature, but an indispensible guide to identifying, understanding and treating this disorder. 508 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493925687 ISBN 13: 9781493925681
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume covers the latest technological advances in the characterization of the biosynthesis and functions of Rab GTPases and their regulation by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). The book consists of 28 chapters and starts with an overview of the Rab GTPase family. The next few chapters describe systematic approaches to the identification and classification of Rabs and Rab GAPs, as well as the detection of Rab isoprenylation and membrane distribution. The last few chapters examine the biochemical and functional properties of individual Rabs in the order of exocytic, recycling and endocytic Rabs. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls.Instructive and practical, Rab GTPases: Methods and Protocols approaches each topic with great detail and is a valuable resource for researchers and students interested in the field of Rab GTPases. 376 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493900439 ISBN 13: 9781493900435
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes a variety of current feedback operational amplifier (CFOA) architectures and their applications in analog signal processing/generation. Coverage includes a comprehensive survey of commercially available, off-the-shelf integrated circuit CFOAs, as well as recent advances made on the design of CFOAs, including design innovations for bipolar and CMOS CFOAs. This book serves as a single-source reference to the topic, as well as a catalog of over 200 application circuits which would be useful not only for students, educators and researchers in apprising them about the recent developments in the area but would also serve as a comprehensive repertoire of useful circuits for practicing engineers who might be interested in choosing an appropriate CFOA-based topology for use in a given application. 268 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1489997512 ISBN 13: 9781489997517
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Historical Archaeology of New York City is a collection of narratives about people who lived in New York City during the seventeenth, eighteenth, and nineteenth centuries, people whose lives archaeologists have encountered during excavations at sites where these people lived or worked. The stories are ethnohistorical or microhistorical studies created using archaeological and documentary data. As microhistories, they are concerned with particular people living at particular times in the past within the framework of world events. The world events framework will be provided in short introductions to chapters grouped by time periods and themes. The foreword by Mary Beaudry and the afterword by LuAnne DeCunzo bookend the individual case studies and add theoretical weight to the volume. Historical Archaeology of New York City focuses on specific individual life stories, or stories of groups of people, as a way to present archaeological theory and research. Archaeologists work with material culture-artifacts-to recreate daily lives and study how culture works; this book is an example of how to do this in a way that can attract people interested in history as well as in anthropological theory. 392 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493926535 ISBN 13: 9781493926534
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Contesting Ethnoarchaeologies provides a systematic overview of major non-American traditions of ethnoarchaeology, with a particular focus on Europe and Asia. It explores all stages of their research agenda. These ethnoarchaeologies were embedded in theoretical traditions of local archaeologies. Moreover, ethnoarchaeological studies carried out in these different settings targeted a wide range of different issues and addressed numerous questions of covering all sorts of different issues. Consequently, achieved results and data have been largely idiosyncratic and hardly compatible. Hence, this volume aims not only to conceptualize characteristics of these diverse ethnoarchaeologies but more importantly put them in a broader context of the development of archaeology in different parts of Europe and Asia. The contributors to the volume express their own diverse views on the cognitive and interpretative value of ethnoarchaeology for studying prehistoric past, based on particular cases of experience and research. As such, the volume is not only a valuable overview of numerous ethnoarchaeological practices in different parts of the region, but also a significant contribution to the history of archaeological thought. This perspective shall make the book of wider applicability and make possible to put up ethnoarchaeology as an immanent and important element of archaeological theory. 264 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493926799 ISBN 13: 9781493926794
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Social and behavioral scientists study religion or spirituality in various ways and have defined and approached the subject from different perspectives. In cultural anthropology and archaeology the understanding of what constitutes religion involves beliefs, oral traditions, practices and rituals, as well as the related material culture including artifacts, landscapes, structural features and visual representations like rock art. Researchers work to understand religious thoughts and actions that prompted their creation distinct from those created for economic, political, or social purposes. Rock art landscapes convey knowledge about sacred and spiritual ecology from generation to generation.Contributors to this global viewdetail how rock art can be employed to address issues regarding past dynamic interplaysof religions and spiritual elements. Studies from a number of different cultural areas and time periods explore how rock artengages the emotions, materializes thoughts and actions and reflects religiousorganization as it intersects with sociopolitical cultural systems. 292 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493902199 ISBN 13: 9781493902194
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In recent years, there has been an explosion of research on the early origins of adult health. A growing body of evidence documents that maternal health before conception, prenatal and perinatal exposures, and conditions in childhood play critical roles in health over the life course. Scientific understanding of the multiple and interacting influences on child health and their role in later health continues to evolve rapidly, but greater attention to how families shape the conditions of early life that underlie childhood health is needed. This volume aims to advance understanding of this topic, with attention to mechanisms through which health disparities emerge and are sustained across the lifespan. 248 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1489991875 ISBN 13: 9781489991874
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Metaheuristics have been a very active research topic for more than two decades. During this time many new metaheuristic strategies have been devised, they have been experimentally tested and improved on challenging benchmark problems, and they have proven to be important tools for tackling optimization tasks in a large number of practical applications. In other words, metaheuristics are nowadays established as one of the main search paradigms for tackling computationally hard problems. Still, there are a large number of research challenges in the area of metaheuristics. These challenges range from more fundamental questions on theoretical properties and performance guarantees, empirical algorithm analysis, the effective configuration of metaheuristic algorithms, approaches to combine metaheuristics with other algorithmic techniques, towards extending the available techniques to tackle ever more challenging problems.This edited volume grew out of the contributions presented at the ninth Metaheuristics International Conference that was held in Udine, Italy, 25-28 July 2011. The conference comprised 117 presentations of peer-reviewed contributions and 3 invited talks, and it has been attended by 169 delegates. The chapters that are collected in this book exemplify contributions to several of the research directions outlined above. 200 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 148999291X ISBN 13: 9781489992918
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes a novel digital calibration technique called dynamic-mismatch mapping (DMM) to improve the performance of digital to analog converters (DACs). Compared to other techniques, the DMM technique has the advantage of calibrating all mismatch errors without any noise penalty, which is particularly useful in order to meet the demand for high performance DACs in rapidly developing applications, such as multimedia and communication systems. 176 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493925091 ISBN 13: 9781493925094
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents cutting-edge techniques to design, fabricate and use compartmentalized microfluidic devices. Chapters encompass axon guidance and manipulation, compartmentalized devices for synapse manipulation, cell populations interaction either in physiological or pathological condition and compartmentalized devices for pharmacological research and drug discovery. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.Authoritative and practical, Microfluidic and Compartmentalized Platforms for Neurobiological Research provides practical skills needed to fabricate, use microfluidics and compartmentalized platforms with neuronal cell cultures as well as the strengths of these exciting devices and their precious contribution in the field of Neuroscience. 264 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493925210 ISBN 13: 9781493925216
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume focuses on detecting different cellular stresses, measuring pathological consequences within the cell, and investigating the role of cellular stresses in select diseases. In addition, this book reviews the crosstalk between different stress pathways, stress responses during ageing, and targeting stress for regenerative medicine. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and instructive, Stress Responses: Methods and Protocols seeks to aid scientists to further study multiple stress pathways and outcomes triggered by such stresses. In depth knowledge of cellular stress will eventually lead to the development of novel therapeutics to prevent or treat related diseases. 260 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493924524 ISBN 13: 9781493924523
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides readers with a comprehensive review of various gene silencing methodologies and its applications. It provides a historical overview of gene silencing mechanisms in plants, vectors, and strategies available for plant gene silencing, practical applications of gene silencing, bioinformatics tools, and other resources. In addition to these review chapters, this book includes methodology for virus-induced gene silencing (VIGS) in various different plant species, understanding plant stress responses using VIGS, miRNA identification, DNA interference, host-induced gene silencing, use of artificial miRNAs for gene silencing, high throughput RNAi, and more. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Thorough and practical, Plant Gene Silencing: Methods and Protocols seeks to aid scientists to further understand functional relevance of target genes using gene silencing methods and use these technologies in commercial plant varieties. 320 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493924583 ISBN 13: 9781493924585
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume describes the methods of both in vivo and in vitro electroporation using ferrets, rats, mice, chickens, and zebrafish. Recent advances of experiments using the tetracycline-regulated gene expression and Tol2 transposon systems are also included. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Practical and authoritative, Electroporation Methods in Neuroscience serves to aid scientists in the further study into this crucially important way to study cells. 212 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493924311 ISBN 13: 9781493924318
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology. 252 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493921584 ISBN 13: 9781493921584
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This vibrant collection delivers a laboratory roadmap of testing cognition in the rodent. While rodents and mazes are the main center and focus of this book, many aspects in the field of learning and memory are discussed and detailed, spanning from the molecular to the human, with every chapter delivering a comprehensive review of historical milestones in order to provide context for past discoveries, new findings, and future studies. Didactic foundations, operational definitions, and theory, as well as practical experimental and apparatus set-up, data analysis, and interpretation instructions are included in the first part of the book, while part two contains step-by-step protocols, troubleshooting, and tips from experts in the field.Authoritative and inspirational, The Maze Book: Theories, Practice, and Protocols for Testing Rodent Cognition serves as a detailed and practical manual for scientists wishing to implement these tools in their laboratories and for scholars interested in this powerful field. 476 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493925466 ISBN 13: 9781493925469
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains state-of-the-art methods tackling all aspects of small non-coding RNAs biology. Small Non-Coding RNAs: Methods and Protocols guides readers through customized dedicated protocols and technologies that will be of valuable help to all those willing to contribute deciphering the numerous functions of small non-coding RNAs. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubles troubleshooting and avoiding known pitfalls.Instructive and practical, Small Non-Coding RNAs: Methods and Protocols reaches out to biochemists, cellular and molecular biologists already working in the field of RNA biology and to those just starting to study small non-coding RNAs. 252 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493923676 ISBN 13: 9781493923670
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph presents the state of the art in aeroservoelastic (ASE) modeling and analysis and develops a systematic theoretical and computational framework for use by researchers and practicing engineers. It is the first book to focus on the mathematical modeling of structural dynamics, unsteady aerodynamics, and control systems to evolve a generic procedure to be applied for ASE synthesis. Existing robust, nonlinear, and adaptive control methodology is applied and extended to some interesting ASE problems, such as transonic flutter and buffet, post-stall buffet and maneuvers, and flapping flexible wing.The author derives a general aeroservoelastic plant via the finite-element structural dynamic model, unsteady aerodynamic models for various regimes in the frequency domain, and the associated state-space model by rational function approximations. For more advanced models, the full-potential, Euler, and Navier-Stokes methods for treating transonic and separated flows are also briefly addressed. Essential ASE controller design and analysis techniques are introduced to the reader, and an introduction to robust control-law design methods of LQG/LTR and H2/H synthesis is followed by a brief coverage of nonlinear control techniques of describing functions and Lyapunov functions. Practical and realistic aeroservoelastic application examples derived from actual experiments are included throughout.Aeroservoelasiticity fills an important gap in the aerospace engineering literature and will be a valuable guide for graduate students and advanced researchers in aerospace engineering, as well as professional engineers, technicians, and test pilots in the aircraft industry and laboratories. 332 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493924672 ISBN 13: 9781493924677
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Wireless sensor Networks: Vehicle and Space Applications describes the practical perspectives in using wireless sensor networks (WSN) to develop real world applications that can be used for space exploration. These applications include sensor interfaces, remote wireless vehicles, space crew health monitoring and instrumentation. The material discusses how applications of WSN originally developed for space travel and exploration are being applied and used in multiple real world applications, allowing for the development of smart systems that have characteristics such as self healing, self diagnosis, and emergency healthcare notification. 260 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 149392446X ISBN 13: 9781493924462
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of this edition is to introduce the beginner to the basics of affinity chromatography and provide practical knowledge for the development of affinity separation protocols. Affinity Chromatography: Methods and Protocols, Third Edition guides readers through new state of the art protocols, molecular modelling, and the study of ligand-target interactions. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Affinity Chromatography: Methods and Protocols, Third Edition is designed as a useful resource for those interested in the rapid and quantitative isolation of biomolecules with high purity. 356 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493923323 ISBN 13: 9781493923328
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides a comprehensive overview of quality metrics and methods used to improve quality for all major modalities of CRC screening. It introduces the readers to the evidence of effectiveness behind various CRC screening modalities: stool-based tests (Fecal Occult Blood, Fecal Immunochemical and Fecal DNA tests), flexible sigmoidoscopy, colonoscopy and CT colonography. In-depth chapters review the latest guidelines for CRC screening, compare differences among the five major national guidelines, and highlight the need for valid quality and cost indicators. While the main focus of this volume is on colonoscopy, since most quality indicators and analyses have focused on this modality of screening and surveillance, one chapter is devoted to quality indicators of other screening modalities. Differences between process and outcome measures are also highlighted and a small but valid set of recommended national measures are listed.Written by experts in the field, Colorectal Cancer Screening: Quality and Benchmarks is an important and useful resource written for gastroenterologists, primary care physicians, general and colorectal surgeons, family physicians, and investigators with research focus in screening and quality metrics. 220 pp. Englisch.
Editore: Springer New York Mrz 2015, 2015
ISBN 10: 1493920464 ISBN 13: 9781493920464
Lingua: Inglese
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
EUR 106,99
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature.Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice. 280 pp. Englisch.