springer new york sep 2011 (582 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From one of the editors of the renowned book Beyond Calculation, acclaimed by The New York Times for its 'astonishing intellectual reach', comes a new collection of equal brilliance. Focusing on the impact of computers on humans, Talking Back to the Machine features essays on how computers will affect the ways we live, learn, teach, communicate, and relate to each other in the coming decades. Outstanding contemporary thinkers describe the myriad ways, both good and bad, in which our lives will be altered by information technology, and what we can do to influence these changes. Talking Back to the Machine is a must-read for anyone who is interested in technology and society. 220 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Starting with an elegant description of a small piece of land called Hungry Hollow, A.K. Dewdney introduces us to its denizens. The reader goes on a guided tour through the many dimensions of our natural habitat, back into prehistoric time and inward to a teeming microscopic world full of strange creatures performing bizarre feats.'It surprised me how 220 pages explaining biological phenomena can add up to a literary image of the magic of lifePerhaps this book will go some way to redress the general deficiency in judgement that allows humans to endanger other life forms.' -NEW SCIENTIST 252 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Human consciousness has perplexed philosophers, artists and scientists for centuries. Some hold it to be purely physical, while others believe it transcends the material world. Now comes a book that offers a new perspective - based entirely on evidence from the natural sciences - whereby materialism and dualism co-exist. The author - a distinguished pioneer of nonlinear dynamics - bases his argument on a hierarchical view of mental organization; a stairway. Atoms give rise to molecules, neurons form the brain and individual consciousness leads to shared culture. All steps are needed to complete the picture and each level derives from the previous one. The book shows specialists how each of their fields adds to the overall picture, while providing general readers with an introduction to this investigation. 252 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For more than a century, oil has been the engine of growth for a society that delivers an unprecedented standard of living to many. We now take for granted that economic growth is good, necessary, and even inevitable, but also feel a sense of unease about the simultaneous growth of complexity in the processes and institutions that generate and manage that growth. As societies grow more complex through the bounty of cheap energy, they also confront problems that seem to increase in number and severity. In this era of fossil fuels, cheap energy and increasing complexity have been in a mutually-reinforcing spiral. The more energy we have and the more problems our societies confront, the more we grow complex and require still more energy. How did our demand for energy, our technological prowess, the resulting need for complex problem solving, and the end of easy oil conspire to make the Deepwater Horizon oil spill increasingly likely, if not inevitable This book explains the real causal factors leading up to the worst environmental catastrophe in U.S. history, a disaster from which it will take decades to recover. 252 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In February 1996, a chess-playing computer known as Deep Blue made history by defeating the reigning world chess champion, Gary Kasparov, in a game played under match conditions. Kasparov went on to win the six-game match 4-2 and at the end of the match announced that he believed that chess computing had come of age. This book provides an enthralling account of the match and of the story that lies behind it: the evolution of chess-playing computers and the development of Deep Blue. The story of chess-playing computers goes back a long way and the author provides a whistlestop tour of the highlights of this history. As the development comes to its culmination in Philadelphia, we meet the Deep Blue team, Garry Kasparov and each of the historic six games is provided in full with a detailed commentary. Chess grandmaster Yasser Seirawan provided a lively commentary throughout the match and here provides a Foreword about the significance of this event. 340 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Every amateur astronomer has at least heard of the many different catalogs of deep-sky objects; the most well known are the Messier, the Caldwell, the Herschel, and the NGC. All of these catalogs are, in general, readily available, but very few amateur observers are in a position to choose the best catalog for their particular deep-sky observing program, know how to use the catalog, or even realize just how many there are out there!The Amateur Astronomer's Guide to the Deep-sky Catalogs is a single compilation of the historical and modern astronomical deep-sky catalogs. It discusses their origins, compares what's in them, explains how to interpret the data they contain, and even outlines how readers can create suitable 'custom' catalogs for their own use. The last section provides a set of three deep-sky catalogs created by the author, for observers of different levels of experience, from newcomer to expert. 392 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume, like the others, not only focuses upon the individual missions within the decade but also upon key challenges facing human space exploration at specific points within those years - from the problems of simply breathing and eating in space to the challenges of venturing outside in a pressurized spacesuit, the development of newer and better space toilets, and the difficulties of locomotion on the Moon.The Eighties was a time when traveling into space far more commonplace. Examining in detail the American and Soviet fronts, Ben Evans gives a comprehensive analysis of the varying fortunes of the U.S. space shuttle in the Eighties, including its early test flights and commercial flights, its problems, the 51L tragedy and its aftermath, and the resumption of operations with STS-26. The U.S. story ends with STS-37 in April 1991. In the Soviet sphere, two pivotal space station efforts - Salyut 7 and its succesor, Mir - are considered, showing how they were alike and different. 496 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -demographic changes and an aging construction work force. Also, an improvement in construction safety could not only reduce accidents but also decrease the cost of the construction, and is therefore one of the imperative goals of the construction industry. These challenges correspond to the potential for Automation and Robotics in Construction as one of solutions. Almost half of construction work is said to be material handling and materials used for construction are heavy and bulky for humans. To date, various types of robots have been developed for glazed panel construction. Through the case studies on constructions, to which the robots were applied, however, we could find some difficulties to be overcome. In this study, a human-robot cooperative system is deduced as one approach to surmount these difficulties and then, considerations on interactions among the operator, robot and environment are applied to design of the system controller. The human-robot cooperative system can cope with various and untypical constructing environment through the real-time interacting with a human, robot and constructing environment simultaneously. The physical power of a robot system helps a human to handle heavy construction materials with relatively scaled-down load. Also, a human can feel and response the force reflected from robot end effecter acting with working environment. Through the experiments and mock-up tests with a prototype robot, we could observe the characteristics of the power assist and the force reflection, the merits of the human-robot cooperation system. To apply human-robot cooperative system at real construction sites, Glazed Ceiling Panel Construction Robot is developed for the first time. This robot is distinguished from other glazed panel construction robots because of the methods of lifting the panel to high installation positions and installing the fragile and bulk panel with robot force control. After application to real construction sites, evaluation on the productivity of the developed robot was done by comparing and analyzing with the existing installation methods. 80 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The subject of this book is the physics of vortices. A detailed analysis of the dynamics of vortices will be presented. The important topics of vorticity and molecular spin will be dealt with, including the electromagnetic analogy and quantization in superfluids. The effect of molecular spin on the dynamics of molecular nano-confined fluids using the extended Navier-Stokes equations will also be covered -especially important to the theory and applicability of nanofluidics and associated devices. The nanoscale boundary layer and nanoscale vortex core are regions of intense vorticity (molecular spin). It will be shown, based on molecular kinetic theory and thermodynamics, that the macroscopic (solid body) rotation must be accompanied by internal rotation of the molecules. Electric polarization of the internal molecular rotations about the local rotation axis -the Barnett effect - occurs. In such a spin aligned system, major changes in the physical properties of the fluid result. 144 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many of the challenges faced by family-owned businesses develop after the firm has reached a stage of maturity, when the first generation is faced with issues concerning the role of their children in the business and the long-term future of the enterprise. This collection of case studies from around the world demonstrates how governance of both the business and the family (or lack thereof) impacts succession of leadership in the firm and the inheritance of ownership and wealth.It is the role of governance and how it impacts both family and firm that link these family business cases together with succession and inheritance. These topics have been clustered together because the social systems of the family and the management system of the firm have significant impacts on the success, or failure, of succession plans. All the planning in the world for succession and inheritance will not succeed if the firm does not have a well established and functional governance system. Likewise, if the family does not understand its role in the governance of the firm and the mechanisms for making sound decisions, succession choices may not be accepted by family members. Most family firms fail because of succession issues, not economic ones.This volume features nine in-depth cases of family-owned business from a variety of industries to illuminate the dynamics of governance, succession, and inheritance. Each case illustrates the complexity of issues and, through interactive exercises and questions, offers readers approaches to solutions, which may include less-than-optimal compromises or even selling the business as the only viable option. The examples and insights will prove valuable for students and members of entrepreneurial and family-owned firms, as well as consultants, investors, and other professional advisors. 136 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Born global' (BG) firms have attracted many researchers throughout the last decade. The emergence of this phenomenon initially posed a serious challenge to the validity and applicability of the traditional 'stage' theory of internationalization; however, scholars have more recently been able to reconcile traditional and new theories into a single framework for studying the process of internationalization. This volume applies both network theory and knowledge-based theory to analyze export assistance in the context of internationalization of low-tech BG firms in developing countries (with an in-depth study of the apparel industry in Bangladesh). The findings that non-governmental network partners provide more useful advice than government agencies is one that may resonate through other countries, including developed economies. Government's more useful role is confined to the financial support and incentives that are provided to such firms. It is, however, the commitment to exporting that emerges as critical for performance, more so than export strategy, suggesting that enhanced export performance is to attract, reassure and motivate entrepreneurs in ways that strengthen their commitment to international expansion. 88 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book will introduce design methodologies, known as Built-in-Self-Test (BiST) and Built-in-Self-Calibration (BiSC), which enhance the robustness of radio frequency (RF) and millimeter wave (mmWave) integrated circuits (ICs). These circuits are used in current and emerging communication, computing, multimedia and biomedical products and microchips. The design methodologies presented will result in enhancing the yield (percentage of working chips in a high volume run) of RF and mmWave ICs which will enable successful manufacturing of such microchips in high volume. 108 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Through practical cases, the author explores, dissect and examine how soft computing may complement conventional techniques in speech enhancement and speech recognition in order to provide robust systems. Includes coverage of synergy between speech technology and bio-inspired soft computing methods. The material is especially useful to graduate students and experienced researchers who are interested in expanding their horizon and in investigating new research directions through a review of the theoretical and practical settings of soft computing methods in very recent speech applications. 116 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the late 1970s and early 1980s, our nation began to grapple with the legacy of past disposal practices for toxic chemicals. With the passage in 1980 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), commonly known as Superfund, it became the law of the land to remediate these sites. The U. S. Department of Defense (DoD), the nation's largest industrial organization, also recognized that it too had a legacy of contaminated sites. Historic operations at Army, Navy, Air Force, and Marine Corps facilities, ranges, manufacturing sites, shipyards, and depots had resulted in widespread contamination of soil, groundwater, and sediment. While Superfund began in 1980 to focus on remediation of heavily contaminated sites largely abandoned or neglected by the private sector, the DoD had already initiated its Installation Restoration Program in the mid 1970s. In 1984, the DoD began the Defense Environmental Restoration Program (DERP) for contaminated site assessment and remediation. Two years later, the U. S. Congress codified the DERP and directed the Secretary of Defense to carry out a concurrent program of research, development, and demonstration of innovative remediation technologies. As chronicled in the 1994 National Research Council report, 'Ranking Hazardous-Waste Sites for Remedial Action', our early estimates on the cost and suitability of existing technologies for cleaning up contaminated sites were wildly optimistic. Original estimates, in 1980, projected an average Superfund cleanup cost of a mere $3. 296 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Remote sensing has witnessed a renaissance as new sensor systems, data collection capabilities and image processing methodologies have expanded the technological capabilities of this science into new and important applications areas. Perhaps nowhere has this trend been more evident than in the study of earth environments. Within this broad application area remote sensing has proven to be an invaluable asset supporting timely data gathering at a range of synoptic scales, facilitating the mapping of complex landscapes and promoting the analysis of environmental process. Yet remote sensing's contribution to the study of human/environmental interaction is scattered throughout a rich and diverse literature spanning the social and physical sciences, which frustrates access to, and the sharing of the knowledge gained through, these recent advances, and inhibits the operational use of these methods and techniques in day to day environmental practice, a recognized gap that reduces the effectiveness of environmental management programs. The objective of this book is to address this gap and provide the synthesis of method and application that is currently missing in the environmental science, re-introducing remote sensing as an important decision-support technology. 348 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book evaluates the newest efforts and initiative aimedat preventing burglary, discusses their merits and short-comings, and suggests how improvements might be incorporatedin burglary prevention programs. 208 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is written for quantitative finance professionals, students, educators, and mathematically inclined individual investors. It is about some of the latest developments in pricing, hedging, and investing in incomplete markets. With regard to pricing, two frameworks are fully elaborated: neutral and indifference pricing. With regard to hedging, the most conservative and relaxed hedging formulas are derived. With regard to investing, the neutral pricing methodology is also considered as a tool for connecting market asset prices with optimal positions in such assets.Srdjan D. Stojanovic is Professor in the Department of Mathematical Sciences at University of Cincinnati (USA) and Professor in the Center for Financial Engineering at Suzhou University (China). 280 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Polygraphy;' 'lie detection;' and the 'detection of deception' are all terms that refer to an application of the science of psychophysiology, which itself employs physiological measures to study and differentiate between psychological processes. The issues raised by polygraphy are controversial. One such issue is whether the polygraph is a genuinely scientifically based application, or merely a purported application, of psychophysiology. Such concerns are of interest not only to polygraph practitioners and to specialists in psychophysiology, but also to such other specialists as those in the legal and forensic professions. Moreover, there are two sorts of nonspecialists who should also be concerned. On the one hand, there are the potential 'users' of the polygraph-for example, a manager who employs a polygrapher to check on subordinates; on the other hand, there are those 'used by' the polygraph - the employee who is subjected to the poly graphic examination. To begin with the user of the polygraph, this person should know not only about its overall accuracy, but also about the rationales of the various detection methods and their validity for different purposes in different sorts of situations. This infor mation is important, because even for the potential user there are costs as well as benefits. Aside from the lack of trust generated by the polygraph, there have also been successful suits by employees against employers, so there are traps in polygraph usage that employers (and managers) need to keep in mind. 184 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -After successfully deciphering the Rongorongo script of Easter Island, Steven Roger Fischer gained a unique place in the pantheon of glyphbreakers: he is the only person to have deciphered not one but two ancient scripts. Both of these scripts yield clues of great historical importance. Fischers previous decipherment, of a Cretan artefact called the Phaistos Disk, provided the key to the ancient Minoan language and showed it to be closely related to Mycenaean Greek. Fischer's decipherment of Rongorongo shows that it was not merely a mnemonic device for recalling memorised texts, but was actually read and used for creative composition. This is the exciting story of these two decipherments, by the man who now must rank as the greatest glyphbreaker of all time. 252 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The basic notion underlying this monograph - budget or revenue constrained models of production - we owe to Ronald W. Shephard, who recognized its fundamental importance in modeling behavior in a wide variety of settings including the service and public sector. Our endeavor here is to extend Shephard's earlier work in several directions while maintaining his axiomatic approach. Our contributions include an expanded set of duality results and a general bent toward empirical implementation: including various parameterizations, applications to efficiency and productivity measurement, and shadow pricing. We hope to provide those engaged in empirical work with some powerful and useful tools which have received relatively little attention. The nature of the material in this monograph is somewhat technical, however, the level of mathematical difficulty is standard. Although we have tried to keep the monograph fairly self-contained, we have also kept technical detail to a minimum in the body of the text. Many technical extensions appear as problems at the ends of Chapters. The reader is also referred to the notes at the end of each chapter for references to additional literature. A prepublication draft of this manuscript was used as lecture notes in a graduate course in production theory at the Department of Economics at Bilkent University. We thank our students as well as faculty members for their patience and interest. Special thanks go to Dean Togan, Zeynap Koksal and Ali Dogramaci for making our stay in Ankara not only productive, but also enjoyable. 184 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With increasing frequency, the proof of facts in legal proceedings en tails the use of quantitative methods. Judges, lawyers, statisticians, social scientists, and many others involved in judicial processes must address is sues such as the evaluation and interpretation of quantitative evidence, the ethical and professional obligations of expert witnesses, and the roles of court-appointed witnesses. The Panel on Statistical Assessments as Evi dence in the Courts was convened to help clarify these issues and provide some guidance in addressing the difficulties encountered in the use of quan titative assessments in legal proceedings. This report is the culmination of more than three years of research and deliberation. In it, we address a variety of issues that arise in federal and state court proceedings when statistical assessments such as quantitative descriptions, causal inferences, and predictions of events based on earlier occurrences are presented as evidence. We appraise the forms in which such assessments are presented, aspects of their admission into evidence, and the response to and evaluation of them by judges and juries. 376 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is intended for second year graduate students and professionals who have an interest in linear and nonlinear simultaneous equations mod els. It basically traces the evolution of econometrics beyond the general linear model (GLM), beginning with the general linear structural econo metric model (GLSEM) and ending with the generalized method of mo ments (GMM). Thus, it covers the identification problem (Chapter 3), maximum likelihood (ML) methods (Chapters 3 and 4), two and three stage least squares (2SLS, 3SLS) (Chapters 1 and 2), the general nonlinear model (GNLM) (Chapter 5), the general nonlinear simultaneous equations model (GNLSEM), the special ca'3e of GNLSEM with additive errors, non linear two and three stage least squares (NL2SLS, NL3SLS), the GMM for GNLSEIVl, and finally ends with a brief overview of causality and re lated issues, (Chapter 6). There is no discussion either of limited dependent variables, or of unit root related topics. It also contains a number of significant innovations. In a departure from the custom of the literature, identification and consistency for nonlinear models is handled through the Kullback information apparatus, as well as the theory of minimum contrast (MC) estimators. In fact, nearly all estimation problems handled in this volume can be approached through the theory of MC estimators. The power of this approach is demonstrated in Chapter 5, where the entire set of identification requirements for the GLSEM, in an ML context, is obtained almost effortlessly, through the apparatus of Kullback information. 424 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Illusion of Reality was conceived during my tenure as director of the newly established Division of Information Science and Technology at the National Science Foundation in 1979-1981 as a partial response to the need for a textbook for students, both in and out of government, that would pro vide a comprehensive view of information science as a fundamental constitu ent of other more established disciplines with a unity and coherence distinct from computer science, cognitive science, and library science although it is related to all of them. Driven by the advances of information technology, the perception of information science has progressed rapidly: today it seems well understood that information processing biological organisms and informa tion processing electronic machines have something basic in common that may subsume the theory of computation, as well as fundamental parts of physics. This book is primarily intended as a text for an advanced undergraduate or a graduate introduction to information science. The multidisciplinary nature of the subject has naturally led to the inclusion of a considerable amount of background material in various fields. The reader is likely to fmd the treat ment relatively oversimplified in fields with which he is familiar and, perhaps, somewhat heavier sailing in less familiar waters. The theme of common principles among seemingly unrelated applications provides the connective tissue for the diverse topics covered in the text and, I hope, justifies the variable level of presentation. Some of the material appears here for the first time. 352 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Family-owned and managed firms are often beset by a variety of crises that can impact the firm's very survival. These may include changes in technology, deaths of critical family members, competition within an industrial sector, shifts in market dynamics and product mixes, economic turmoil, political upheaval and revolution, firm growth, succession, and selecting new firm leadership. Such crises may be internal to the firm or a function of the external environment, and several may occur simultaneously; all of them contribute to a context of uncertainty, risk, and change, presenting particular challenges that are unique to family-owned businesses.This volume presents eight in-depth case studies of family-owned firms that represent a variety of industries and situations. Each case explores the dynamics of managing in chaotic environments and how family leadership responded to crises. Lessons learned from these experiences will help readers understand how to solve problems under conditions of uncertainty and how to avoid failure, when the survival of the firm is at stake. Featuring questions and learning notes designed to engage the reader directly, this volume will be a valuable resources for students and members of entrepreneurial and family-owned firms, as well as consultants, investors, and other professional advisors. 112 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Modern radar, telecommunication, sonar, and radio-astronomy systems use integrated systems, complex signals, and signal processing methods exten sively. These systems require the development of new, more efficient systems. One of the major ways to improve radar and sonar systems is to use multichannel systems, the most promising of which employ space-time signal processing. In the last few years the intensive growth in electronics, informa tion processing techniques, microwave and laser technology, electrooptics and holography, acoustics, and optoelectronics have resulted in new scientific and technological research fronts. One of these is the theory and technology of electrooptical array antennas-a new class of receiving antennas whose pat tern is controlled by means of coherent optics and holography. Electrooptical array theory and technology have been involved in the study of the power, resolution, and range characteristics of arrays with various coherent opti cal processors. The practical applications of these systems and methods for building them using contemporary optoelectronics have also been studied. 344 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mechanical engineering, an engineering discipline born of the needs of the industrial revolution, is once again asked to do its substantial share in the call for industrial renewal. The general call is urgent as we face profound issues of productivity and competitiveness that require engineering solutions, among others. The Mechanical Engineering Series is a series featuring graduate texts and research monographs intended to address the need for information in contemporary areas of mechanical engineering. The series is conceived as a comprehensive one that covers a broad range of concentrations important to mechanical engineering graduate education and research. We are fortunate to have a distinguished roster of consulting editors, each an expert in one of the areas of concentration. The names of the consulting editors are listed on the following page of this volume. The areas of concentration are applied mechanics, biomechanics, computational mechanics, dynamic systems and control, energetics, mechanics of materials, processing, thermal science, and tribology. Professor Winer, the consulting editor for tribology, and I are pleased to present this volume of the series: Laminar Viscous Flow, by Professor Constantinescu. The selection of this volume underscores again the interest of the Mechanical Engineering Series to provide our readers with topical monographs as well as graduate texts. 508 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and Inhibitors The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline) represent one class of such agents. This volume is for pharmacologists, biochemists, and medical chemists in research labs of universities, gov- ernment, and the pharmaceutical industry. 468 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Malignant hyperthermia is a genetic disease that causes an extremely high body temperature. The syndrome is triggered by depolarizing muscle relaxants and halogenated gaseous anesthetics, such as halothane. The purpose of the book is to present the latest experimental work and important conclusions to anesthesiologists, surgeons, certified registered nurse anesthesists, operating nurses, cardiovascular and temperature oriented physiologists, basic research scientists interested in heat production in muscle, animal scientists, primarily swine physiologists, and finally, muscle biology scientists. The results are based on sixteen years of experimental investigations with a malignant hyperthermia susceptible pig colony. Consequently, the data and conclusions are more concrete than the clinical data from human patients. The first five chapters present fresh material relating to the detailed biochemical mechanism of heat production during malignant hyperthermia. Subsequent chapters present recent data on malignant hyperthermia in horses and dogs; these additional animal models provide useful material for future studies of malignant hyperthermia pathophysiology. Later sections summarize the laboratory methods currently used for diagnosing malignant hyperthermia in human patients and present valuable data on malignant hyperthermia in the greater Kansas city area over a twenty year period. 184 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -International concern in scientific, industrial, and governmental communi ties over traces of xenobiotics in foods and in both abiotic and biotic envi ronments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published research papers and progress reports, and archival documentations. These three international publications are integrated and scheduled to provide the coherency essential for nonduplicative and current progress in a field as dynamic and complex as environmental contamination and toxicology. This_series is reserved ex clusively for the diversified literature on ''toxic'' chemicals in our food, our feeds, our homes, recreational and working surroundings, our domestic animals, our wildlife and ourselves. Tremendous efforts worldwide have been mobilized to evaluate the nature, presence, magnitude, fate, and toxi cology of the chemicals loosed upon the earth. Among the sequelae of this broad new emphasis is an undeniable need for an articulated set of authoritative publications, where one can find the latest important world literature produced by these emerging areas of science together with docu mentation of pertinent ancillary legislation. Research directors and legislative or administrative advisers do not have the time to scan the escalating number of technical publications that may contain articles important to current responsibility. Rather, these individu als need the background provided by detailed reviews and the assurance that the latest information is made available to them, all with minimal literature searching. 188 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this research monograph, the noted scholar Dr. Gordon K. Klintworth brings together all the available information on the pathogenesis of corneal neovascularization. This book should be a valuable contribution to the medical literature of ophthalmology and clinical pathology. Despite its relatively simple structure the cornea possesses many unique properties. These attributes include its crystal clarity and avascularity in the health state. This normally transparent structure has been the focal point for Dr. Klintworth's research endeavors for more than two decades. This monograph summarizes current knowledge about angiogenesis within this tissue as well as information about the related issue of the cornea's normal avascularity. The text provides a comprehensive overview of the topic based on studies by a large number of investigators who were either concerned with corneal neovascularization in particular or angiogenesis in general. 152 pp. Englisch.