springer us sep 2016 (311 risultati)

Taschenbuch. Condizione: Neu. Neuware -In this volume expert researchers detail in silico methods widely used to study peptides. These include methods and techniques covering the database, molecular docking, dynamics simulation, data mining, de novo design and structure modeling of peptides and protein fragments. Chapters focus on integration and application of technologies to analyze, model, identify, predict, and design a wide variety of bioactive peptides, peptide analogues and peptide drugs, as well as peptide-based biomaterials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Computational Peptidology seeks to aid scientists in the further study into this newly rising subfield.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 352 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Automatic detection and segmentation of anatomical structures in medical images are prerequisites to subsequent image measurements and disease quantification, and therefore have multiple clinical applications. This book presents an efficient object detection and segmentation framework, called Marginal Space Learning, which runs at a sub-second speed on a current desktop computer, faster than the state-of-the-art. Trained with a sufficient number of data sets, Marginal Space Learning is also robust under imaging artifacts, noise and anatomical variations. The book showcases 35 clinical applications of Marginal Space Learning and its extensions to detecting and segmenting various anatomical structures, such as the heart, liver, lymph nodes and prostate in major medical imaging modalities (CT, MRI, X-Ray and Ultrasound), demonstrating its efficiency and robustness.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book describes recent innovations in 3D media and technologies, with coverage of 3D media capturing, processing, encoding, and adaptation, networking aspects for 3D Media, and quality of user experience (QoE). The contributions are based on the results of the FP7 European Project ROMEO, which focuses on new methods for the compression and delivery of 3D multi-view video and spatial audio, as well as the optimization of networking and compression jointly across the future Internet. The delivery of 3D media to individual users remains a highly challenging problem due to the large amount of data involved, diverse network characteristics and user terminal requirements, as well as the user¿s context such as their preferences and location. As the number of visual views increases, current systems will struggle to meet the demanding requirements in terms of delivery of consistent video quality to fixed and mobile users. ROMEO will present hybrid networking solutions that combine the DVB-T2 and DVB-NGH broadcast access network technologies together with a QoE aware Peer-to-Peer (P2P) distribution system that operates over wired and wireless links. Live streaming 3D media needs to be received by collaborating users at the same time or with imperceptible delay to enable them to watch together while exchanging comments as if they were all in the same location.This book is the second of a series of three annual volumes devoted to the latest results of the FP7 European Project ROMEO. The present volume provides state-of-the-art information on immersive media, 3D multi-view video, spatial audio, cloud-based media, networking protocols for 3D media, P2P 3D media streaming, and 3D Media delivery across heterogeneous wireless networks among other topics. Graduate students and professionals in electrical engineering and computer science with an interest in 3D Future Internet Media will find this volume to be essential reading.Describes the latestinnovations in 3D technologies and Future Internet MediaFocuses on research to facilitate application scenarios such as social TV and high-quality, real-time collaborationDiscusses QoE for 3DRepresents the last of a series of three volumes devoted to contributions from FP7 projects in the area of 3D and networked mediaSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 260 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book provides an introduction to incorporating preference information in Data Envelopment Analysis (DEA) with a special emphasis in Value Efficiency Analysis. In addition to theoretical considerations, numerous illustrative examples are included. Hence, the book can be used as a teaching text as well. Only a modest mathematical background is needed to understand the main principles. The only prerequisites are a) familiarity with linear algebra, especially matrix calculus; b) knowledge of the simplex method; and c) familiarity with the use of computer software.The book is organized as follows. Chapter 1 provides motivation and introduces the basic concepts. Chapter 2 provides the basic ideas and models of Data Envelopment Analysis. The efficient frontier and production possibility set concepts play an important role in all considerations. That's why these concepts are considered more closely in Chapter 3. Since the approaches introduced in this study are inspired by Multiple Objective Linear Programming, the basic concepts of this field are reviewed in Chapter 4. Chapter 5 also compares and contrasts Data Envelopment Analysis and Multiple Objective Linear Programming, providing some cornerstones for approaches presented later in the book. Chapter 6 discusses the traditional approaches to take into account preference information in DEA. In Chapter 7, Value Efficiency is introduced, and Chapter 8 discusses practical aspects. Some extensions are presented in Chapter 9, and in Chapter 10 Value Efficiency is extended to cover the case when a production possibility set is not convex. Three implemented applications are reviewed in Chapter 11.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 204 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -While this book contains numerous facts and empirical findings and touches on policy issues, its main contribution to the existing literature lies in the theoretical perspective it offers. The core of this book is a general equilibrium theory of labor and marriage presented in Chapter 2, which provides the conceptual framework for the rest of the chapters. Two major implications of the theory are sex ratio effects and compensating differentials in marriage. The book demonstrates how a few core concepts, linked via economic analysis, help explain a multitude of findings based on statistical analyses of data from a wide variety of cultures. It is hoped that readers of this book will improve their understanding of how marriage works to help us design better economic and social policies as well as help people live better and happier lives, making the book of interest to not only economists but sociologists and anthropologists as well.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book provides a complete analysis of educational production and costs using the nonparametric technique known as Data Envelopment Analysis (DEA). The book focuses on estimation of technical, allocative and scale efficiency in the public sector characterized by the influence of exogenous socio-economic variables. State of the art DEA models will be presented and fully discussed. Specific education topics important to policy makers including adequacy, technical, allocative and scale efficiency, productivity and environmental costs will be analyzed. To illustrate how these techniques can be applied to school systems worldwide, the authors use data on Australian elementary and high schools to develop nonparametric measures that will help inform current policy debate in Australia.The purpose of the book is to provide a comprehensive analysis of educational production using numerous public sector DEA models. We provide a review of DEA with SAS programming code to estimate technical, scale and allocative efficiency in chapter 2. In chapter 3, we extend the DEA models to control for exogenous factors of production. SAS code is also provided to estimate all public sector models. We use simulated data to illustrate the results. Chapters 4¿6 provide a complete analysis of the primary and secondary schools. We analyze input and output oriented models and derive measures of technical, allocative and scale efficiency. We also provide estimates of environmental costs that arise from schools facing different operating environments based on socioeconomic conditions. In addition, we show how DEA can provide insight on adequacy¿the minimum cost of providing a pre-defined adequate education. The models presented are consistent with public sector production in general and educational production in particular. We also provide a complete analysis of educational productivity for both primary and secondary schools using state of the art public sector Malmquistmeasures. The authors use current data on Australian schools to highlight important policy questions related to efficiency and productivity given concerns that schools are not allocatively scarce resources in an economic efficient way.This research focus comes at an important watershed moment in the Australian Federal Governments¿ current involvement in designing new nationally consistent funding models for both government and non-government schooling sectors with effect from 2014. A new National School Resourcing Standard is proposed to be implemented signaling a move to resource adequacy, school efficiency and value for money dimensions. These standards are consistent with the measures presented and estimated in this book. As a result, the models implemented in this book can serve as the basis to evaluate the funding changes associated with the transition from a ¿centralized¿ to a new ¿decentralized¿ set of school funding arrangements.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 164 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Transformation from Wall Street to Well-being:Joining up the dots through Participatory democracy and governance to mitigate the causes and adapt to the effects of climate changeaddresses accountable leadership, supports collective interests, ethical governance and fairness to future generations in order to develop systemic approaches relevant to these issues. The humanistic focus, whilst central, addresses how we see ourselves in relation to the environment. It explores cultural perspectives in developed and developing parts of the world where people have a closer connection with the natural environment in comparison to those who live in cities. Furthermore the book discusses participatory action research to prefigure a means to hold the market to ensure that the use of resources that are necessary for the common good are accessible and equitable. The essential systemic aim this book offers is to balance human needs with nature. The research summarizes the discourses and the adaptive praxis in order to develop a bridge between cosmopolitan ethics and cosmopolitan governance. It does this in the interest of supporting and using cultural designs for living that support quality of life and spans five core domains as explained by the author. Overall, this monograph helps evaluates the extent to which the introduced approaches enable the community to consider their perceived assets and risks and the implications of their consumption choices.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume presents relevantbackground information to understanding the molecular basis governingunconventional protein secretion (UPS), and in particular explores the latesttechniques and protocols that have been successfully applied for the study ofthis topic. Detailed chapters include an overview of conventional andunconventional secretory pathways along with multidisciplinary approaches andmethods used for UPS analysis in different organisms. Written in the highly successful Methods inMolecular Biology series format,chapters include introductions to theirrespective topics, lists of the necessary materials and reagents, step-by-stepreadily reproducible laboratory protocols, and tips on troubleshooting andavoiding known pitfalls.Authoritative and cutting-edge, UnconventionalProtein Secretion: Methods and Protocols will beusefulfor all interested in the secretory pathway field as well as applications incell biology, cell development, biomedical research, and healthcare.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 288 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This text integrates different mobility data handling processes, from database management to multi-dimensional analysis and mining, into a unified presentation driven by the spectrum of requirements raised by real-world applications. It presents a step-by-step methodology to understand and exploit mobility data: collecting and cleansing data, storage in Moving Object Database (MOD) engines, indexing, processing, analyzing and mining mobility data. Emerging issues, such as semantic and privacy-aware querying and mining as well as distributed data processing, are also covered. Theoretical presentation is smoothly interchanged with hands-on exercises and case studies involving an actual MOD engine. The authors are established experts who address both theoretical and practical dimensions of the field but also presentvaluable prototype software. The background context, clear explanations and sample exercises make this an ideal textbook for graduate students studying database management, data mining and geographic information systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 316 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Distributions in the Physical and Engineering Sciences is a comprehensive exposition on analytic methods for solving science and engineering problems. It is written from the unifying viewpoint of distribution theory and enriched with many modern topics which are important for practitioners and researchers. The goal of the books is to give the reader, specialist and non-specialist, useable and modern mathematical tools in their research and analysis.Volume 2: Linear and Nonlinear Dynamics of Continuous Media continues the multivolume project which endeavors to show how the theory of distributions, also called the theory of generalized functions, can be used by graduate students and researchers in applied mathematics, physical sciences, and engineering. It contains an analysis of the three basic types of linear partial differential equations--elliptic, parabolic, and hyperbolic--as well as chapters on first-order nonlinear partial differential equations and conservation laws, and generalized solutions of first-order nonlinear PDEs. Nonlinear wave, growing interface, and Burger¿s equations, KdV equations, and the equations of gas dynamics and porous media are also covered.The careful explanations, accessible writing style, many illustrations/examples and solutions also make it suitable for use as a self-study reference by anyone seeking greater understanding and proficiency in the problem solving methods presented. The book is ideal for a general scientific and engineering audience, yet it is mathematically precise.Features Application oriented exposition of distributional (Dirac delta) methods in the theory of partial differential equations. Abstract formalism is keep to a minimum. Careful and rich selection of examples and problems arising in real-life situations. Complete solutions to all exercises appear at the end of the book. Clear explanations, motivations, and illustration of all necessary mathematical concepts.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 436 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Engineering Viscoelasticity covers all aspects of the thermo- mechanical response of viscoelastic substances that a practitioner in the field of viscoelasticity would need to design experiments, interpret test data, develop stress-strain models, perform stress analyses, design structural components, and carry out research work. The material in each chapter is developed from the elementary to the esoteric, providing the background in mathematics and mechanics that are central to understanding the subject matter being presented. This book also examines how viscoelastic materials respond to the application of loads, and provides practical guidelines to use them in the design of commercial, military and industrial applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Contingency tables arise in diverse fields, including life sciences, education, social and political sciences, notably market research and opinion surveys. Their analysis plays an essential role in gaining insight into structures of the quantities under consideration and in supporting decision making.Combining both theory and applications, this book presents models and methods for the analysis of two- and multidimensional-contingency tables. The author uses a threefold approach, presenting fundamental models and related inference, highlighting their interpretational aspects, and demonstrating their practical usefulness.Emphasis is on applications and methods of fitting models using standard statistical tools - such as SPSS, R, and BUGS - and on interpretation of the results.An excellent reference for advanced undergraduates, graduate students, and practitioners in statistics as well as biosciences, social sciences, education, and economics, the work may also be used as a textbook for a course on categorical data analysis. Prerequisites include basic background on statistical inference and knowledge of statistical software packages.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 324 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book presents a new approach to the analysis of networks, which emphasizes how one can compress a network while preserving all information relative to the network's spectrum. Besides these compression techniques, the authors introduce a number of other isospectral transformations and demonstrate how, together, these methods can be applied to gain new results in a number of areas. This includes the stability of time-delayed and non time-delayed dynamical networks, eigenvalue estimation, pseudospectra analysis and the estimation of survival probabilities in open dynamical systems. The theory of isospectral transformations, developed in this text, can be readily applied in any area that involves the analysis of multidimensional systems and is especially applicable to the analysis of network dynamics. This book will be of interest to Mathematicians, Physicists, Biologists, Engineers and to anyone who has an interest in the dynamics of networks.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book provides a framework for computational researchers studying the basics of cancer through comparative analyses of omic data. It discusses how key cancer pathways can be analyzed and discovered to derive new insights into the disease and identifies diagnostic and prognostic markers for cancer. Chapters explain the basic cancer biology and how cancer develops, including the many potential survival routes. The examination of gene-expression patterns uncovers commonalities across multiple cancers and specific characteristics of individual cancer types. The authors also treat cancer as an evolving complex system, explore future case studies, and summarize the essential online data sources. Cancer Bioinformatics is designed for practitioners and researchers working in cancer research and bioinformatics. It is also suitable as a secondary textbook for advanced-level students studying computer science, biostatistics or biomedicine.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 396 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The purpose of the corona workshop was toconsider the corona problem in both one and several complex variables, both in the context of function theory and harmonic analysis as well as the context of operator theory and functional analysis. It was held in June 2012 at the Fields Institute in Toronto, and attended by about fifty mathematicians. This volume validates and commemorates the workshop, and records some of the ideas that were developed within. The corona problem dates back to 1941. It has exerted a powerful influence over mathematical analysis for nearly 75 years. There is material to help bring people up to speed in the latest ideas of the subject, as well as historical material to provide background. Particularly noteworthy is a history of the corona problem, authored by the five organizers, that provides a unique glimpse at how the problem and its many different solutions have developed. There has never been a meeting of this kind, and there has never been a volume of this kind. Mathematicians¿both veterans and newcomers¿will benefit from reading this book. This volume makes a unique contribution to the analysis literature and will be a valuable part of the canon for many years to come.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This handbook consists of seventeen chapters written by eminent scientists from the international mathematical community, who present important research works in the field of mathematical analysis and related subjects, particularly in the Ulam stability theory of functional equations. The book provides an insight into a large domain of research with emphasis to the discussion of several theories, methods and problems in approximation theory, analytic inequalities, functional analysis, computational algebra and applications.The notion of stability of functional equations has its origins with S. M. Ulam, who posed the fundamental problem for approximate homomorphisms in 1940and with D. H. Hyers, Th. M. Rassias, who provided the first significant solutions for additive and linear mappings in 1941 and 1978, respectively. During the last decade the notion of stability of functional equations has evolved into a very active domain of mathematical research with several applications of interdisciplinary nature.The chapters of this handbook focus mainly on both old and recent developments on the equation of homomorphism for square symmetric groupoids, the linear and polynomial functional equations in a single variable, the Drygas functional equation on amenable semigroups, monomial functional equation,the Cauchy¿Jensen type mappings, differential equations and differential operators, operational equations and inclusions, generalized module left higher derivations, selections of set-valued mappings, D¿Alembert¿s functional equation, characterizations of information measures,functional equations in restricted domains, as well as generalized functional stability and fixed point theory.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 408 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This pioneering text provides a comprehensive introduction to systems structure, function, and modeling as applied in all fields of science and engineering. Systems understanding is increasingly recognized as a key to a more holistic education and greater problem solving skills, and is also reflected in the trend toward interdisciplinary approaches to research on complex phenomena. While the concepts and components of systems science will continue to be distributed throughout the various disciplines, undergraduate degree programs in systems science are also being developed, including at the authors¿ own institutions. However, the subject is approached, systems science as a basis for understanding the components and drivers of phenomena at all scales should be viewed with the same importance as a traditional liberal arts education.Principles of Systems Science contains many graphs, illustrations, side bars, examples, and problems to enhance understanding. Frombasic principles of organization, complexity, abstract representations, and behavior (dynamics) to deeper aspects such as the relations between information, knowledge, computation, and system control, to higher order aspects such as auto-organization, emergence and evolution, the book provides an integrated perspective on the comprehensive nature of systems. It ends with practical aspects such as systems analysis, computer modeling, and systems engineering that demonstrate how the knowledge of systems can be used to solve problems in the real world. Each chapter is broken into parts beginning with qualitative descriptions that stand alone for students who have taken intermediate algebra. The second part presents quantitative descriptions that are based on pre-calculus and advanced algebra, providing a more formal treatment for students who have the necessary mathematical background. Numerous examples of systems from every realm of life, including the physical and biological sciences,humanities, social sciences, engineering, pre-med and pre-law, are based on the fundamental systems concepts of boundaries, components as subsystems, processes as flows of materials, energy, and messages, work accomplished, functions performed, hierarchical structures, and more. Understanding these basics enables further understanding both of how systems endure and how they may become increasingly complex and exhibit new properties or characteristics.Serves as a textbook for teaching systems fundamentals in any discipline or for use in an introductory course in systems science degree programsAddresses a wide range of audiences with different levels of mathematical sophisticationIncludes open-ended questions in special boxes intended to stimulate integrated thinking and class discussionDescribes numerous examples of systems in science and societyCaptures the trend towards interdisciplinary research and problem solvingSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 792 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book opens new avenues in understanding mathematical models within the context of a transition economy. The exposition lays out the methods for combining different mathematical structures and tools to effectively build the next model that will accurately reflect real world economic processes. Mathematical modeling of weather phenomena allows us to forecast certain essential weather parameters without any possibility of changing them. By contrast, modeling of transition economies gives us the freedom to not only predict changes in important indexes of all types of economies, but also to influence them more effectively in the desired direction. Simply put: any economy, including a transitional one, can be controlled.This book is useful to anyone who wants to increase profits within their business, orimprove the quality of their family life and the economic area they live in. It is beneficial for undergraduate and graduate students specializing in the fields of Economic Informatics, Economic Cybernetics, Applied Mathematics and Large Information Systems, as well as for professional economists, and employees of state planning and statistical organizations.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Receptor Tyrosine Kinases: Methods and Protocols explores on the most widely studied of the protein classes, known for their central role in several cellular functions and in a variety of human pathologies. Beginning with a section on activation and signaling of Receptor Tyrosine Kinases (RTKs), the book continues with chapters on aberrant expression of RTKs, trafficking and negative regulation, as well as RTKs as pharmacological targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Receptor Tyrosine Kinases: Methods and Protocols contains an up-to-date overview of the most relevant and widely used methods employed in this field, providing detailed protocols that molecular and cellular biologists could easily adopt in their research programs on RTKs.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 196 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book covers the issues of monitoring, failure localization, and restoration in the Internet optical backbone, and focuses on the progress of state-of-the-art in both industry standard and academic research. The authors summarize, categorize, and analyze the developed technology in the context of Internet fault management and failure recovery under the Generalized Multi-Protocol Label Switching (GMPLS), via both aspects of network operations and theories.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book presents a unique approach not found in any other text for those looking to improve the clinical results of refractive surgery by gaining a better understanding of corneal biomechanics and the instrumentation related to it. Written by leading experts in the field, this book provides authoritative coverage of the interactions of the cornea and the bioinstrumentation, such as corneal topography, pachymetry, aberrometers, tonometry and optical coherence tomography.Organized in an easy-to-read manner, Corneal Biomechanics and Refractive Surgery is designed for refractive surgeons and general ophthalmologists alike and describes the biomechanical role of the corneal tissue and how each part is affected in refractive surgery. Additionally, showing what the bioinstrumentation can measure, how models can improve understanding of the interaction between biomechanics, bioinstrumentation, and refractive surgery, and how these models and bioinstrumentation together can improve the refractive results, are also discussed.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 156 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book presents fundamental concepts and seminal results to the study of vortex filaments in equilibrium. It also presents new discoveries in quasi-2D vortex structures with applications to geophysical fluid dynamics and magnetohydrodynamics in plasmas. It fills a gap in the vortex statistics literature by simplifying the mathematical introduction to this complex topic, covering numerical methods, and exploring a wide range of applications with numerous examples. The authors have produced an introduction that is clear and easy to read, leading the reader step-by-step into this topical area. Alongside the theoretical concepts and mathematical formulations, interesting applications are discussed. This combination makes the text useful for students and researchers in mathematics and physics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 152 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This volume provides complete coverage of the computational approaches currently used in Synthetic Biology. Chapters focus on computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.Authoritative and practical, Computational Methods in Synthetic Biology serves as a guide to plan in silico the in vivo or in vitro construction of a variety of synthetic bio-circuits.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 372 pp. Englisch.

Buch. Condizione: Neu. Neuware -This unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases, Biology and Management of Unusual Plasma Cell Dyscrasias will be a long-lasting reference for clinicians and scientists alike.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 216 pp. Englisch.

Buch. Condizione: Neu. Neuware -This comprehensive reference delves into the complex process of medical decision making¿both the nuts-and-bolts access and insurance issues that guide choices and the cognitive and affective factors that can make patients decide against their best interests. Wide-ranging coverage offers a robust evidence base for understanding decision making across the lifespan, among family members, in the context of evolving healthcare systems, and in the face of life-changing diagnosis. The section on applied decision making reviews the effectiveness of decision-making tools in healthcare, featuring real-world examples and guidelines for tailored communications with patients. Throughout, contributors spotlight the practical importance of the field and the pressing need to strengthen health decision-making skills on both sides of the clinician/client dyad.Among theHandbook¿s topics: From laboratory to clinic and back: connecting neuroeconomic and clinical measures of decision-making dysfunctions. Strategies to promote the maintenance of behavior change: moving from theoretical principles to practices.Shared decision making and the patient-provider relationship.Overcoming the many pitfalls of communicating risk. Evidence-based medicine and decision-making policy.The internet, social media, and health decision making.The Handbook of Health Decision Sciencewill interest a wide span of professionals, among them health and clinical psychologists, behavioral researchers, health policymakers, and sociologists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The Digital Da Vinci book series opens with the interviews of music mogul Quincy Jones, MP3 inventor Karlheinz Brandenburg, Tommy Boy founder Tom Silverman and entertainment attorney Jay L. Cooper. A strong supporter of science, technology, engineering and mathematics programs in schools, The Black Eyed Peas founding member will.i.am announced in July 2013 his plan to study computer science. Leonardo da Vinci, the epitome of a Renaissance man, was an Italian polymath at the turn of the 16th century. Since the Industrial Revolution in the 18th century, the division of labor has brought forth specialization in the workforce and university curriculums. The endangered species of polymaths is facing extinction. Computer science has come to the rescue by enabling practitioners to accomplish more than ever in the field of music. In this book, Newton Lee recounts his journey in executive producing a Billboard-charting song like managing agile software development; M. Nyssim Lefford expounds producing and its effect on vocal recordings; Dennis Reidsma, Mustafa Radha and Anton Nijholt survey the field of mediated musical interaction and musical expression; Isaac Schankler, Elaine Chew and Alexandre François describe improvising with digital auto-scaffolding; Shlomo Dubnov and Greg Surges explain the use of musical algorithms in machine listening and composition; Juan Pablo Bello discusses machine listening of music; Stephen and Tim Barrass make smart things growl, purr and sing; Raffaella Folgieri, Mattia Bergomi and Simone Castellani examine EEG-based brain-computer interface for emotional involvement in games through music and last but not least, Kai Ton Chau concludes the book with computer and music pedagogy. Digital Da Vinci: Computers in Music is dedicated to polymathic education and interdisciplinary studies in the digital age empowered by computer science. Educators and researchers ought to encourage the new generation of scholars to become as well rounded as aRenaissance man or woman.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Evidence pertaining to continual violence throughout the life cycle coupled with the experience of growing old in a life permeated by intimate violence is scarce. And the focus is usually on the victims ¿ usually, the older, battered women ¿ and seldom on their aging partners or adult children who were part and parcel of the violent dynamics in the family system. With the increase in longevity and the older population¿s subsequent growth in size, the number of elderly couples living and aging in long-lasting conflictive relationships is on the rise.The relatively intense preoccupation with elder abuse in the gerontological literature in recent years has not specifically addressed long-term intimate violence among the old adults and its lasting consequences. Similarly, the literature on intimate intergenerational relationships in old age has usually focused on normative exchanges between partners and their extended family, including their adult children. Therefore, conflictive relationships, and particularly violent ones, have also fallen outside the scope of this body of research. This volume describes and analyzes the various perspectives of family members concerning life, and particularly old age, in the shadow of long-term intimate violence. It explores how people make sense out of living and aging in violence, how interpersonal, familial and cross-generational relationships are perceived and reconstructed and how ¿we-ness¿ is achieved, if at all, in such families.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 152 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -In this book the authors introduce and explain many methods and models for the development of Information Systems (IS). It was written in large part to aid designers in designing successful devices/systems to match user needs in the field. Chief among these are website development, usability evaluation, quality evaluation and success assessment. The book provides great detail in order to assist readers¿ comprehension and understanding of both novel and refined methodologies by presenting, describing, explaining and illustrating their basics and working mechanics. Furthermore, this book presents many traditional methods and methodologies in an effort to make up a comprehensive volume on High Level Models and Methodologies for Information Systems.The target audience for this book is anyone interested in conducting research in IS planning and development. The book represents a main source of theory and practice of IS methods and methodologies applied to these realities. The book will appeal to a range of professions that are involved in planning and building the information systems, for example information technologists, information systems developers, as well as Web designers and developers¿both researchers and practitioners; as a consequence, this book represents a genuinely multi-disciplinary approach to the field of IS methods and methodologies.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 164 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The Nature of Language addresses one of the most fundamental questions of mankind: how did language evolve, and what are the neurobiological and cognitive foundations of language processing These questions are explored from different perspectives to discuss the building blocks of language evolution and how they developed in the way they can be found in modern humans. Primarily, neural mapping methods of cognition presented in this research provide extremely valuable data about the neural circuitries that are involved in language processing. Thus, the book explores and illustrates cortical mapping in typical language patterns, but also cortical mapping in atypical populations that fail to process particular language aspects. A neurobiological stance is used to inquire about how language abilities of our species evolved to communicate for the purposes of conveying information such as ideas, emotions, goals, and humor.The evolutionary language model presented builds on the cognitive abilities of our ancestors, and it allows readers to draw a variety of expansive conclusions from that, including the idea that human language as an interface system provides the basis for consciousness.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book discusses current research on identity formation, family and peer influences, risk and resilience factors, and concepts of masculinity and sexuality in African American boys. Sorting out genuine findings from popular misconceptions and misleading headlines, this concise and wide-ranging reference covers the crucial adolescent years, ages 11-16, acknowledging diversity of background and experience in the group, and differences and similarities with African American girls as well as with other boys. In addition, the authors review strengths-based school and community programs that harness evidence and insights to promote pro-social behavior.Featured areas of coverage include:The protective role of ethnic identity and racial socialization.Family management, cohesion, communication, and well-being.Development and importance of peer relationships.Health and well-being.Theoretical perspectives on educational achievement.Factors that contribute to delinquency and victimization.What works: effective programs and practices.African American Boys is an essential resource for a wide range of clinicians and practitioners¿ as well as researchers and graduate students ¿ in school and clinical child psychology, prevention and public health, social work, mental health therapy and counseling, family therapy, and criminal justice.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 188 pp. Englisch.