Articoli correlati a Genetic diversity of benign breast tumors among Senegalese...
- EditoreLAP LAMBERT Academic Publishing
- Data di pubblicazione2016
- ISBN 10 3659824712
- ISBN 13 9783659824715
- RilegaturaCopertina flessibile
- Numero di pagine68
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Da: Germania a: U.S.A.
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Genetic diversity of benign breast tumors among Senegalese women
Editore:
LAP Lambert Academic Publishing Feb 2016
(2016)
ISBN 10: 3659824712
ISBN 13: 9783659824715
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Descrizione libro Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In Sub-Saharan Africa, as in Senegal, breast cancer is the second after that of cervical in women. However, although most of the studies on breast pathology concern cancer, the overwhelming majority of breast lesions, palpable or not are benign. Thus this research is done in order to understand the impact of diversity and genetic evolution of the D-loop in benign breast lesions in Senegalese women. The variability of the D-loop was investigated and the results revealed a significant presence of specific variants for breast benign tissue. The C150T mutation was associated with protection to the presence of benign breast tumors when G247A implicated in an increased risk. Patients of mitochondrial haplogroup L would be significantly more susceptible to these benign breast lesions. Finally, a significant correlation was associated with haplotypes C309CC and witnessed the D310, which respectively constitute increased risk groups and susceptible to the contraction of benign breast lesions. All these results allowed to have a global view on the influence of pathogenic mutations on diversity and genetic evolution of the D-Loop observed in Senegalese patients with benign breast tumor. 68 pp. Englisch. Codice articolo 9783659824715
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Genetic diversity of benign breast tumors among Senegalese women
Editore:
LAP Lambert Academic Publishing
(2016)
ISBN 10: 3659824712
ISBN 13: 9783659824715
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Taschenbuch
Quantità: 1
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Descrizione libro Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In Sub-Saharan Africa, as in Senegal, breast cancer is the second after that of cervical in women. However, although most of the studies on breast pathology concern cancer, the overwhelming majority of breast lesions, palpable or not are benign. Thus this research is done in order to understand the impact of diversity and genetic evolution of the D-loop in benign breast lesions in Senegalese women. The variability of the D-loop was investigated and the results revealed a significant presence of specific variants for breast benign tissue. The C150T mutation was associated with protection to the presence of benign breast tumors when G247A implicated in an increased risk. Patients of mitochondrial haplogroup L would be significantly more susceptible to these benign breast lesions. Finally, a significant correlation was associated with haplotypes C309CC and witnessed the D310, which respectively constitute increased risk groups and susceptible to the contraction of benign breast lesions. All these results allowed to have a global view on the influence of pathogenic mutations on diversity and genetic evolution of the D-Loop observed in Senegalese patients with benign breast tumor. Codice articolo 9783659824715
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Genetic diversity of benign breast tumors among Senegalese women
Editore:
LAP LAMBERT Academic Publishing
(2016)
ISBN 10: 3659824712
ISBN 13: 9783659824715
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Descrizione libro Condizione: New. Codice articolo 158124525
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