ISBN 10: 1420092383 / ISBN 13: 9781420092387
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This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Summary: This revised third edition has been updated to cover all aspects of chiral drugs from the academic, governmental industrial and clinical perspective reflecting the many advances in techniques and methodology. The title will cover new material including the use of enzymes for the synthesis and resolution of enantiomeric compounds as well as their use in drug discovery; how stereochemistry impacts on decisions taken during the ADMET (absorption, distribution, metabolism, excretion, toxicity) stage of drug discovery; issues faced during the final stages of the drug development process; the impact of ICH (International Conference on Harmonisation) on the use of single isomer drugs; racemic switches; and legal perspectives looking at IP and patent issues surrounding racemic switches and marketing single enantiomer switches. Codice inventario libreria

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Riassunto:

Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition covers all aspects of chiral drugs from academic, governmental, industrial, and clinical perspectives, reflecting the many advances in techniques and methodology.

Topics include:

  • The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery
  • How stereochemistry impacts decisions made in the absorption, distribution, metabolism, excretion, and toxicity (ADMET) stages of drug discovery
  • Pharmacokinetics and pharmacodynamics and the issues faced during the final stages of the drug development process
  • The impact of the International Conference on Harmonisation (ICH) on the use of single isomer drugs
  • Chiral switches
  • The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs
  • Patent issues surrounding chiral switches and the marketing of single enantiomer switches

The book provides a solid background on stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. It is a one-stop reference for pharmaceutical scientists and chemists working with chiral drug molecules.

Sinossi:

Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition has been updated to cover all aspects of chiral drugs from the academic, governmental, industrial, and clinical perspectives reflecting the many advances in techniques and methodology.

New topics include:

  • The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery
  • How stereochemistry impacts decisions made in the absorption, distribution, metabolism, excretion, and toxicity (ADMET) stages of drug discovery
  • A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process
  • The impact of International Conference on Harmonisation (ICH) on the use of single isomer drugs
  • Chiral switches
  • The concept of molecular chiral recognition and how it affects the separation and behavior o stereochemically pure drugs
  • A chapter on the legal perspectives of patent issues surrounding chiral switches and the marketing of single enantiomer switches

This third edition covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. The book is a one-stop shop for pharmaceutical scientists and chemists working with chiral drug molecules.

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Jozwiak
ISBN 10: 1420092383 ISBN 13: 9781420092387
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Descrizione libro Condizione libro: Brand New. Brand New Paperback International Edition, Perfect Condition. Printed in English. Excellent Quality, Service and customer satisfaction guaranteed!. Codice libro della libreria AIND-32242

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Descrizione libro Condizione libro: Brand New. U.S.Edition ,Brand New,Hardcover,Perfect Condition. Printed in English. excellent Quality, and customer satisfaction guaranteed. NO CD ROM & NO ACCESS CODE.We Do not Ship APO FPO AND PO BOX. Codice libro della libreria ABEKHST173

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Descrizione libro Condizione libro: Brand New. PAPERBACK,Book Condition New, Brand New, Softcover, International Edition. We Do not Ship APO FPO AND PO BOX.NOT LOOSE LEAF VERSION,NO SOLUTION MANUAL, NO CD, NO ACCESS CARD Cover Image & ISBN may be different from US edition but contents as US Edition. Printing in English language. Quick delivery by USPS/UPS/DHL/FEDEX/ARAMEX ,Customer satisfaction guaranteed. We may ship the books from Asian regions for inventory purpose. Codice libro della libreria ABEJULNAD117

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Krzysztof Jozwiak, W. J. Lough, Irving W. Wainer
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Descrizione libro Hardcover. Condizione libro: New. Brand New Book, 332 Pages, READY TO SHIP BUY WITH CONFIDENCE, Note:***WE DO NOT ENTERTAIN BULK ORDERS.***. Codice libro della libreria 391471

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Descrizione libro Hardcover. Condizione libro: New. Brand New Book. Codice libro della libreria 26131

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Descrizione libro Taylor & Francis. Condizione libro: Like New. This is an Int'l Edition. Please note: We do not ship to PO Boxes, please provide us with your complete delivery address. Codice libro della libreria LNDXPCBS1MAR-10515

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Descrizione libro Taylor & Francis. Condizione libro: New. This is an Int'l Edition. Please note: We do not ship to PO Boxes, please provide us with your complete delivery address. Codice libro della libreria DXPCBS1MAR-10515

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Irving W. Wainer,Krzysztof Jozwiak,W. John Lough
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Descrizione libro CBS Publishers & Distributors Pvt. Ltd., 2012. Hardcover. Condizione libro: New. 3rd edition. This revised third edition has been updated to cover all aspects of chiral drugs from the academic, governmental industrial and clinical perspective reflecting the many advances in techniques and methodology. The title will cover new material including the use of enzymes for the synthesis and resolution of enantiomeric compounds as well, as their use in drug discovery; how stereochemistry impacts on decisions taken during the ADMET (absorption, distribution, metabolism, excretion, toxicity) stage of drug discovery; issues faced during the final stages of the drug development process; the impact of ICH (International Conference on Harmonisation) on the use of single isomer drugs; racemic switches; and legal perspectives looking at IP and patent issues surrounding chiral switches and marketing single enantiomer switches. This Third Edition comprehensively presents all aspects of chiral drugs from scientific, academic, governmental, industrial, and clinical points of view. This one-stop text covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. New topics include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery How stereochemistry impacts decisions made in the Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) stages of drug discovery A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process The impact of International Conference on Harmonisation on the use of single isomer drugs Chiral switches The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs A chapter on the legal perspectives of patent issues surrounding chiral switches and the marketing of single enantiomer switches This will be a one-stop shop for pharmaceutical scientists and chemists working with chiral drug molecules Printed Pages: 322. Codice libro della libreria 89403

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Irving W. Wainer,Krzysztof Jozwiak,W. John Lough
Editore: CBS Publishers & Distributors Pvt. Ltd. (2012)
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Descrizione libro CBS Publishers & Distributors Pvt. Ltd., 2012. Hardcover. Condizione libro: New. 3rd edition. This revised third edition has been updated to cover all aspects of chiral drugs from the academic, governmental industrial and clinical perspective reflecting the many advances in techniques and methodology. The title will cover new material including the use of enzymes for the synthesis and resolution of enantiomeric compounds as well, as their use in drug discovery; how stereochemistry impacts on decisions taken during the ADMET (absorption, distribution, metabolism, excretion, toxicity) stage of drug discovery; issues faced during the final stages of the drug development process; the impact of ICH (International Conference on Harmonisation) on the use of single isomer drugs; racemic switches; and legal perspectives looking at IP and patent issues surrounding chiral switches and marketing single enantiomer switches. This Third Edition comprehensively presents all aspects of chiral drugs from scientific, academic, governmental, industrial, and clinical points of view. This one-stop text covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. New topics include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery How stereochemistry impacts decisions made in the Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) stages of drug discovery A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process The impact of International Conference on Harmonisation on the use of single isomer drugs Chiral switches The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs A chapter on the legal perspectives of patent issues surrounding chiral switches and the marketing of single enantiomer switches This will be a one-stop shop for pharmaceutical scientists and chemists working with chiral drug molecules Printed Pages: 322. Codice libro della libreria 89403

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