A presentation of the technology for studying human chromosomes, this text serves as a basic techniques manual designed to show the current working protocols in cytogenetics. It details tissue culture procedures for all tissue types from blood to solid tumours, with subsequent chapters providing coverage of chromosome preparations, differential staining techniques, chromosome sorting, high-resolution banding, fragile X analysis, sister chromatoid exchanges and DNA replication. This edition includes a new chapter entitled "Molecular Cytogenetic Techniques" which covers fluorescent in-site hybridization (FISH) procedures, and is illustrated by 20 colour plates.
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