Methods in Cell Biology: Functional Organization of the Nucleus - A Laboratory Guide: 35

Wilson, Leslie; Hamkalo, Barbara A.

ISBN 10: 0123219205 ISBN 13: 9780123219206

Casa editrice: Academic Pr, 1997

Riassunto

The complex problem of the relationship between nuclear structure and function demands a multidisciplinary, multifaceted approach. This laboratory guide is designed for researchers, from graduate students to professors, who need detailed protocols and general discussions on a broad range of techniques. The volume presents a selection of different methodological approaches for the analysis of nuclear structure and function - from cytological to molecular to genetic. These include visualization of nucleic acid sequences using hybridization probes, visualization of proteins using immunological probes, isolation of chromatin fractions, mapping in vitro protein-DNA interactions, reconstitution of functional templates and nuclear substructures, and genetic approaches to identifying and characterizing chromosomal components.

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Dettagli dell'edizione

• Editore: Academic Pr
• Data di pubblicazione: 1997
• Lingua: Inglese
• ISBN 10: 0123219205
• ISBN 13: 9780123219206
• Rilegatura: Pettine di plastica
• Numero di pagine: 590
• Redattore: Elgin Sarah C. R.
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile