Osteoimmunology: Interactions of the Immune and Skeletal Systems - Rilegato

Rilegato

ISBN 10: 0123756707 ISBN 13: 9780123756701

Casa editrice: Academic Pr, 2010

Riassunto

"The new textbook of osteoimmunology provides a comprehensive introduction to this recently established field that seeks to bridge two-well established disciplines. By reviewing both well-established concepts in bone biology and recent advances in our understanding of the interactions between the immune and skeletal systems, the text serves as both an excellent introduction to the field and a state of the art summary. Overall, each chapter provides concise history of work in the area, thus both immunologists and bone biologists can gain a view of how current paradigms evolved to their current states. This makes the book of particular use to trainees that have studied primarily immunology or bone biology in the past but know little about the other. Early chapters focus on specific cell types in the bone such as osteoclasts or osteoblasts and review both the cellular differentiation and function and our current knowledge regarding immune regulation of the cells. Later chapters nicely focus on specific pathologic states in the bone such as inflammatory arthritis or fracture healing and provide a comprehensive review of studies investigating the role of the immune system in these models. The field of osteoimmunology is rapidly expanding and evolving quickly, this textbook will help put all of us on the same page and help us understand how we got here."-Mary C. Nakamura M.D., Associate Professor of Medicine, UCSF, Division of Rheumatology, San Francisco, CA, USA

Su questo libro

Informazioni sull?autore

Joseph Lorenzo, MD - Professor of Medicine in the Division of Endocrinology and Metabolism and Director of Bone Biology Research at the University of Connecticut Health Center, Farmington, CT, USA. He is a nationally renowned expert on bone remodeling and its effect on bone health.
Yongwon Choi, PhD - Leonard Jarett Professor of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. His recent research focuses on molecular understanding of how dendritic cells and osteoclasts differentiate, and of how T cell tolerance is maintained in vivo.
Mark Horowitz, PhD - Professor of Orthopedics and Rehabilitation at the Yale University School of Medicine, New Haven, CT, USA. His research interests include the interactions between the skeletal, immune, and hematopoietic systems as they relate to normal and pathologic bone remodeling.
Hiroshi Takayanagi, MD, PhD - Professor in the Department of Cell Signaling, Tokyo Medical and Dental University, Tokyo, Japan. His group studies the mechanism of bone destruction in rheumatoid arthritis, which focuses on the regulation of osteoclasts by T cells, as well as the signal transduction mechanism in osteoclast differentiation.

Dalla quarta di copertina

"Edited by four pioneers in the field of osteoimmunology, this book contains chapters by 44 outstanding experts, spanning the breadth and depth of our current knowledge of osteoimmunology from cell and molecular biology to clinical problems."

--Tatsuo Suda, Member of the Japan Academy, Associate Member, Science Council of Japan, Emerutus Professor of Showa University, Visiting Professor, Research Center for Genomic Medicine, Saitama Medical University, Japan

"The new textbook of osteoimmunology provides a comprehensive introduction to this recently established field that seeks to bridge two-well established disciplines.

By reviewing both well-established concepts in bone biology and recent advances in our understanding of the interactions between the immune and skeletal systems, the text serves as both an excellent introduction to the field and a state of the art summary. Overall, each chapter provides concise history of work in the area, thus both immunologists and bone biologists can gain a view of how current paradigms evolved to their current states. This makes the book of particular use to trainees that have studied primarily immunology or bone biology in the past but know little about the other. Early chapters focus on specific cell types in the bone such as osteoclasts or osteoblasts and review both the cellular differentiation and function and our current knowledge regarding immune regulation of the cells. Later chapters nicely focus on specific pathologic states in the bone such as inflammatory arthritis or fracture healing and provide a comprehensive review of studies investigating the role of the immune system in these models. The field of osteoimmunology is rapidly expanding and evolving quickly, this textbook will help put all of us on the same page and help us understand how we got here."

--Mary C. Nakamura M.D., Associate Professor of Medicine, UCSF, Division of Rheumatology, San Francisco, CA, USA

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"Edited by four pioneers in the field of osteoimmunology, this book contains chapters by 44 outstanding experts, spanning the breadth and depth of our current knowledge of osteoimmunology from cell and molecular biology to clinical problems."

--Tatsuo Suda, Member of the Japan Academy, Associate Member, Science Council of Japan, Emerutus Professor of Showa University, Visiting Professor, Research Center for Genomic Medicine, Saitama Medical University, Japan

"The new textbook of osteoimmunology provides a comprehensive introduction to this recently established field that seeks to bridge two-well established disciplines.

By reviewing both well-established concepts in bone biology and recent advances in our understanding of the interactions between the immune and skeletal systems, the text serves as both an excellent introduction to the field and a state of the art summary. Overall, each chapter provides concise history of work in the area, thus both immunologists and bone biologists can gain a view of how current paradigms evolved to their current states. This makes the book of particular use to trainees that have studied primarily immunology or bone biology in the past but know little about the other. Early chapters focus on specific cell types in the bone such as osteoclasts or osteoblasts and review both the cellular differentiation and function and our current knowledge regarding immune regulation of the cells. Later chapters nicely focus on specific pathologic states in the bone such as inflammatory arthritis or fracture healing and provide a comprehensive review of studies investigating the role of the immune system in these models. The field of osteoimmunology is rapidly expanding and evolving quickly, this textbook will help put all of us on the same page and help us understand how we got here."

--Mary C. Nakamura M.D., Associate Professor of Medicine, UCSF, Division of Rheumatology, San Francisco, CA, USA

Dettagli dell?edizione

• Editore: Academic Pr
• Data di pubblicazione: 2010
• Lingua: Inglese
• ISBN 10: 0123756707
• ISBN 13: 9780123756701
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 453
• Redattore: Lorenzo Joseph M.D., Choi Yongwon, Horowitz Mark Ph.D., Takayanagi Hiroshi
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile