Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.
This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality.
* Major families of eukaryotic transcription factors described
* Mechanisms of gene activation and repression analysed
* Structure-function relationships indicated
* Interaction between transcription factors and chromatin structure described
* Roles in inducible and cell type-specific gene expression
* Roles in development, differentiation and human diseases including cancer
* Methods of study in vitro and in vivo
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Praise for Previous Editions "A standard for the genre...presented with great clarity...profusely illustrated...admirably up-to-date." (The Lancet)From the Back Cover:
Revised and completely up-to-date, the Third Edition of Eukaryotic Transcription Factors has been extensively rewritten to reflect the rapid advances in the field. These include the emerging roles of specific co-activator molecules such as CBP in the action of a number of different transcription factors emphasizing particularly their ability to modulate chromatin structure. New sections cover current methods for determining DNA binding specificity, regulation by protein degradation and processing, Pax family transcription factors, and novel anti-oncogenic transcription factors, as well as a discussion of transcription factors in human diseases. A special new colour section illustrates the various aspects of transcription factor structure.
Emphasising common motifs, themes and mechanisms this volume covers:
* Major families of eukaryotic transcription factors
* Mechanisms of gene activation and repression
* Structure-function relationships
* Their roles in inducible and cell type-specific gene expression, development, differentiation, and human diseases including cancer
* Methods of study in vivo and in vitro
Essential reading for all those who seriously wish to understand the impact of molecular biology on medicine, whatever their specialty.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
Descrizione libro Academic Press Inc, 1991. Paperback. Condizione libro: Good. Sent within 24 hours. Expedited UK delivery available. Codice libro della libreria BBI2416367
Descrizione libro Academic Press Inc, 1991. Paperback. Condizione libro: Very Good. In VERY GOOD overall condition, with some signs of previous ownership. Daily dispatch from UK warehouse. Codice libro della libreria mon0000104636
Descrizione libro Academic Press Inc, 1991. Condizione libro: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. In fair condition, suitable as a study copy. Codice libro della libreria 3377107
Descrizione libro Academic Press, 1991. Paperback. Condizione libro: Used: Good. Paperback - 1991 - good condition - - used books, secondhand books, out of print books, hard to find books, for sale, second-hand books, college books, student books, nonfiction, first edition, exlibrary books sold, , non-fiction books delivered world wide. 0-12-437171-X. Isbn 012437171X. Familiarity with the mechanisms of eukaryotic gene regulation is now essential for scientists and students in both clinical and basic disciplines. However, the vast array of transcription factors, which are central to such regulation, can prove daunting to students and newcomers to this fascinating field of molecular genetics. The Third Edition of Eukaryotic Transcription Factors provides the reader with a clear and concise understanding not only of transcription factors, but also of their vital role in the regulation of transcription in different cell types during development and in disease. Codice libro della libreria 9376
Descrizione libro Academic Press, London, 1991. Hardcover. Condizione libro: Good. Condizione sovraccoperta: No Dust Jacket. No dust jacket. Hardcover. Ex-Academic Library (Oxford University). Library labels on spine foot and front pastedown. Library barcode label on front endpaper. Library stamps on front endpaper, reverse of title page and page block. Laminated boards and spine with several scores. Small sticker on rear board. Some wear and bumping on spine ends and leading corners. Pages are a little tanned around edges. Contents are clear throughout. Binding is sound. AF. Ex-Library. Codice libro della libreria 434523