Chromatography has today become an integral part of the biotechnology industry, playing a vital role in the purification of biologicals from natural sources as those produced by recombinant DNA and hybridoma techniques. This book is intended as a practical guide and reference source for all those involved in the development of economic chromatographic purification processes. Its purpose extends beyond the description of individual methods to teach the integration of steps, both up and downstream, that lead to a complete process for the successful purification of a desired protein. Researchers, advanced students, senior technicians, and process plant managers working in the biotechnology, biochemical, and pharmaceutical industries will find this text indispensible.
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