Dosage Form Design Parameters (2): Volume II - Rilegato
Libro 2 di 7: Advances in Pharmaceutical Product Development and Research
Sinossi
Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.
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Informazioni sull?autore
Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.
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Dosage Form Design Parameters, Volume 2 (Advances in Pharmaceutical Product Development and Research)
Editore:
Academic Press, 2018
ISBN 10: 0128144211
ISBN 13: 9780128144213
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Hardcover. Condizione: Good. 1st Edition. Oversized hardcover, shipping weight over 2kg (please note: extra postage may be required), xix + 794 pages, NOT ex-library. Printed in the UK. Book is clean and bright with the appearance of little wear; unmarked text, free of inscriptions and stamps, firmly bound. A short crease in the upper outer corner of a portion of leaves. Boards show short corner creases, a long horizontal wrinkle in the protective laminate on the front panel. Issued without a dust jacket. -- An end-to-end guide to dosage form design - from solid-state properties and processability to IVIVC, high-throughput PK, and ADMET - with practical coverage of statistics (ANOVA), sterilization, packaging, documentation, IP, and ethics for translating lab discovery into market-ready products. -- This book provides a complete roadmap from drug substance to market-ready dosage form. It starts with solid-state fundamentals - polymorphism, crystallization, and strategic use of the amorphous state - and links particulate and bulk properties to processability and product performance. A distinctive, hands-on statistics core equips readers to design robust experiments and defend results, covering hypothesis testing, experimental design (DoE/ANOVA), and sound sampling. The formulation-biology interface follows: drug-excipient compatibility, in vitro-in vivo correlation (IVIVC), and modern high-throughput pharmacokinetic analysis. The final modules address the operational and regulatory ecosystem - sterilization, packaging material selection, regulatory documentation, food and drug law, intellectual property, and research ethics - plus advanced tools such as computer-aided ADMET prediction and guidance on software use and licensing. Integrating theory, data, and practice, the volume helps scientists turn laboratory discovery into reliable products and regulatory success. Ideal for researchers, advanced students, and industry professionals in pharmaceutical sciences and product development. -- In an era where drug development faces unprecedented challenges - ranging from escalating R&D costs and regulatory hurdles to the demand for personalized medicines - mastering dosage form design is more crucial than ever. This volume stands out for its holistic approach, combining the foundational sciences (material properties, statistical rigor) with cutting-edge applications (high-throughput screening, computer-aided predictions) and indispensable industry insights (regulatory compliance, intellectual property). It's an invaluable resource for innovating within the pharmaceutical sciences, for anyone invested in the future of drug development. Codice articolo 012100
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Dosage Form Design Parameters: Volume II
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