The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students.
Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers.
The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques.
An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.
Online Resource Centre
The Online Resource Centre features:
For registered adoptors of the book:
· Answers to end-of-chapter questions
· Figures from the book
· Power Point slides
· Test Bank questions
· Hyperlinked bibliography
· Six-monthly updates to text
· 3D Rotatable structures
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Descrizione libro Oxford University Press, 2009. Condizione libro: New. Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: 1. Drugs and drug targets: an overviewPART A: Drug targets: Structure and Function2. Protein structure and function3. Enzymes: structure and function4. Receptors: structure and function5. Receptors and signal transduction6. Nucleic acids - structure and functionPART B: Pharmacodynamics and pharmacokinetics7. Enzymes as drug targets8. Receptors as drug targets9. Nucleic acids as drug targets10. Other drug targets11. Pharmacokinetics and related topicsCase study 1: StatinsPART C: Drug discovery, design, and development12. Drug discovery: finding a lead13. Drug design: optimizing target interactions14. Drug design: optimizing access to the target15. Drug developmentCase study 2: The design of ACE inhibitorsCase study 3: Artemisinin and related antimalarial drugsCase study 4: The design of oxamniquinePART D: Tools of the trade16. Combinatorial synthesis17. Computers in medicinal chemistry18. Quantitative structure-activity relationships (QSAR)Case study 5: De novo design of a thymidylate synthase inhibitorCase study 6: Design of a serotonin antagonistPART E: Selected topics in medicinal chemistry19. Antibacterial agents20. Antiviral agents21. Anticancer agents22. The peripheral nervous system: cholinergics, anticholinergics, and anticholinesterases23. The andrenergic nervous system24. The opium analgesics25. Anti-ulcer agents. Codice libro della libreria ABE_book_new_0199234477
Descrizione libro Oxford University Press, 2009. Paperback. Condizione libro: New. book. Codice libro della libreria 0199234477
Descrizione libro Oxford University Press, USA, 2009. Paperback. Condizione libro: New. 4th. Codice libro della libreria DADAX0199234477
Descrizione libro Oxford University Press. PAPERBACK. Condizione libro: New. 0199234477 New book with very minor shelf wear. STUDENT US EDITION. Never used. Nice gift. Best buy. Shipped promptly and packaged carefully. Codice libro della libreria SKU5002789
Descrizione libro Oxford University Press. PAPERBACK. Condizione libro: New. 0199234477 New Condition. Codice libro della libreria NEW4.0083075
Descrizione libro Oxford University Press, 2009. Paperback. Condizione libro: New. Codice libro della libreria P110199234477
Descrizione libro Oxford University Press, 2009. Condizione libro: New. Nuevo! Fast delivery! Professional service with friendly customer support 7 days a week. Codice libro della libreria 9780199234479