Lesk, Arthur Introduction to Genomics

ISBN 13: 9780199564354

Introduction to Genomics

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9780199564354: Introduction to Genomics

Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life?

Introduction to Genomics is a fascinating insight into what can be revealed from the study of genomes: how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.

Covering the latest techniques that enable us to study the genome in ever-increasing detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism. Learning features throughout make this book the ideal teaching and learning tool: extensive end of chapter exercises and problems help the student to fully grasp the concepts being presented, while end of chapter weblems (web-based problems) and lab assignments give the student the opportunity to engage with the subject in a hands-on manner.

The field of genomics is enabling us to analyze life in more detail than ever before; Introduction to Genomics is the perfect guide to this enthralling subject.

Online Resource Centre
The Online Resource Centre to accompany Introduction to Genomics features

For lecturers:
Figures from the book in electronic format

For students:
Answers to end-of-chapter exercises
Guided tour of web sites in genomics
Hints to end-of-chapter problems
Rotating figures

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Recensione:

Introduction to Genomics provides an excellent, broad and comprehensive overview of genomics research in biology. The field of genomics is highly technology driven and moves extremely fast and this book stands out in translating all this technological information into biological, meaningful concepts. It is highly appropriate to support genomics education to undergraduates. ( Dr Dick Roelofs, VU University, Amsterdam)

Review from previous edition This is an excellent book for students studying this exciting and fast paced subject. It has a number of chapters covering all aspect of genomics, from comparative genomics and evolution to mapping, sequencing and databases through to microarrays and proteomics, finally bringing it all together with systems biology. Suitable for final year undergraduates and masters students, it will also make a good reference book for PhD students ( Dr Dawn L. Arnold, University of the West of England,)

Clearly written and easy to navigate. Thanks to its wide scope, it not only serves as a useful introduction to the field but can also be used to understand how many other key biology topics have changed in recent years as a consequence of the genomics age. A very good resource for undergraduates looking to understand the current state of molecular biology. ( Penny Sarchet, Student, University of Oxford in THE, 2012)

Contenuti:

  • 1: Introduction to Genomics
  • 2: Genomes are the Hub of Biology
  • 3: Mapping, Sequencing, Annotation, and Databases
  • 4: Comparitive Genomics
  • 5: Evolution and Genomic Change
  • 6: Genomes of Prokaryotes
  • 7: Genomes of Eukaryotes
  • 8: Genomics and Human Biology
  • 9: Microarrays and Transcriptomics
  • 10: Proteomics
  • 11: Systems Biology

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