Polypeptide hormones play a central role in the regulation of biological processes from the control of vital functions to the programming of birth, development, reproduction and ageing. This text covers topics relating to the biosynthesis, processing and secretion of polypeptides, and the major signalling systems which mediate hormone action.
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Together, Peptide Hormone Action: A Practical Approach and its companion volume, Peptide Hormone Secretion: A Practical Approach, provide both a detailed compendium of laboratory methods and a source of experimental ideas that will appeal to the novice and expert alike.
The Practical Approach series occupy a valuable niche in Biochemistry and Cell/Molecular Biology ... The present volume, which maintains the generally high standard of the series, is a companion to 'Peptide Hormone Secretion' ... the volume can be particularly recommended to research students or more senior workers who are just commencing a project involving the mechanism of action of an extracellular messenger, even if it is not a peptide hormoneR. (FEBS Letters)
S. Gammeltoft: Peptide hormone secretion; J.L. Treadway & J. Pessin: Receptor characterization; T. Laskey, G. Murphy, & N. Pyne: Cyclic nucleotides; M.B. Hallett, R.L. Dormer, & A.K. Campbell: Cytoplasmic free calcium: measurement and manipulation in living cells; C.J. Kirk, A.J. Morris, & S.B. Shears: Inositol phosphate second messengers; R.V. Farese: Lipid related second messengers; M.F. White: The insulin receptor tyrosine kinase.
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