This second book in the trio describes techniques for analysing the signalling mechanisms of neurotransmitter and hormone receptors. Specific practical guidance is provided in the measurement of the main varieties of receptor response. The book also provides a guide to the science behind the protocols, and includes contributions from some of the most active scientists in this diverse field. It is the first time that this range of techniques have been brought together in such a coordinated manner.
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'the methods and protocols are accurate and well described and should allow a newcomer to use them as such ... I highly recommend this book for all students and researchers working in the field ... The reasonable price should allow many labs to acquire this very useful book.' Professor Dumont, Universite Libre de Bruxelles, Methods in Molecular and Cellular Biology, Vol.2, No.5
'... I highly recommend this book for all students and researchers working in the field. The reasonable price should allow many labs to acquire this very useful book.' Methods in Molecular and Cellular Biology
'As with other volumes in this series, the accent is on the methodology and practical details, which are very helpful.' International Journal of Biochemistry
'Dr. Hulme has edited this book in a very clear manner such that the various chapters, although written by different authors, appear in very similar style. This is a most important job for editors of such practical volumes and makes the reading of the book much more easy ... it is, typically of the practical approach series, extremely good value for money.' Robin E. Leake, FEB Letters, Volume 297, number 3, February 1992
'it will be a useful bench companion for researchers and advanced students in biochemistry, pharmacology, neuroscience, and molecular biology'Anticancer Researcher 12:(1992)
`It is the first volume of its kind to provide practical instruction for measurement of the main varieties of receptor response, as well as a guide to the science behind the methods. As such it will be a useful bench companion for researchers and advanced students in biochemistry, pharmocology, neuroscience and molecular biology.'Anticancer Research
K. Oldham: Polyphosphoinositide turnover; D. Poyner: Receptor-G protein complexes in solution; P. Sternweis, & I.H. Pang: Preparation of G-proteins and their subunits; R. Cerione: Reconstitution of B-adrenergic receptor-G-protein interactions; K. Haga, & T. Haga: Reconstitution of muscarinic receptor-G-protein interactions; A. Gurney: Measurement and control of intracellular calcium; L. Mahadevan, & John C. Bell: Phosphate labelling studies of receptor tyrosine kinases; J. Benovic: Receptors as kinase substrates; A. Gurney: Molecular pharmacology of ion channels using the patch clamp
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