Signal Transduction: A Practical Approach: 102 - Rilegato

Rilegato

ISBN 10: 0199632960 ISBN 13: 9780199632961

Casa editrice: Irl Pr, 1992

Riassunto

Cellular trans-membrane signalling mechanisms are amongst the most highly studied processes in the biological sciences. G-proteins provide transduction components to allow communication between receptors for hormones and neurotransmitters and their effector systems which include enzymes involved in the generation of intracellular secondary messengers and a variety of ion channels. "Signal Transduction: A Practical Approach" details the experimental approaches which are used to define the contacts between receptors and G-proteins and between these G-proteins and their effector systems. While much emphasis in the cellular signalling field remains on the measurement of adenylyl cyclase and of phosphoinositidase C activities, it is now clear that activation of G-protein linked to receptors can also cause the regulation of phospholipases of the D and A2 classes. Thus, assays used to measure the activities of these enzyme systems are detailed in this book. The use of mutagenesis to define functional domains of G-proteins themselves has undergone considerable progress recently and examples of this approach are also provided. This volume is designed to provide a useful guide to the newcomer to the subject, as well as allowing workers already in the field to expand the range of approaches in use in their laboratories.

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Dettagli dell'edizione

• Editore: Irl Pr
• Data di pubblicazione: 1992
• Lingua: Inglese
• ISBN 10: 0199632960
• ISBN 13: 9780199632961
• Rilegatura: Copertina rigida
• Numero di pagine: 205
• Redattore: Milligan Graeme
• Contatto del produttore: non disponibile
• Persona responsabile: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; 20090; Italia