Provides a broad overview of the diverse approaches encompassed by the emerging discipline of molecular epidemiology. Concepts and methods at the forefront of infectious disease studies are discussed along with recent advances in studying host genetics, methods for the detection of mutations and polymorphisms, the relationship between pathologies and immune system genetics, and the use of D.N.A. sequence information to garner insights into the evolution of infectious pathogens. The evolution and function of the immune system and a synopsis of general epidemiological design and analysis are included.
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Each chapter has been written with new researchers in mind, with an easily navigable layout and succinct definitions of specialist terms. The examples provided are presented well and the authors successfully avoid redundant statements, making the information accessible and easy to digest...Molecular Epidemiology was a delight to read and would be invaluable for an undergraduate module. (Journal of Biological Education, 2002, 36 (3))
Mary Carrington is at National Cancer Institute, Frederick, Maryland, U.S.A. . Rus Hoelzel is at Department of Biological Sciences, University of Durham, U.K. .
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