Monoclonal Antibodies Hybridomas: A New Dimension in Biological Analyses - Rilegato

Kennett, Roger H.; McKearn, Thomas J.

 
9780306404085: Monoclonal Antibodies Hybridomas: A New Dimension in Biological Analyses
Rilegato
ISBN 10: 0306404087 ISBN 13: 9780306404085
Casa editrice: Plenum Pub Corp, 1980

Sinossi

On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing "Continuous cultures of fused cells secreting antibody of predefined specificity. " Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im­ munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi­ gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler and Milstein introduced this new technology, the editors of this volume were involved in the production of antisera against differentiation antigens (K. B. B. ), histocompatibility antigens (T. ]. McK. ), and human tumor­ associated antigens (R. H. K. ). Because of the potential usefulness of monoclonal antibodies in these areas, we each began production of hybridomas and analysis of the resulting monoclonal reagents. One of the most interesting aspects of participation in the early stages of the development and application of hybrid­ oma technology has been observing how the implications of the initial observa­ tions gradually spread first among the practitioners of immunology and immu­ nogenetics, and then to other areas of the biological sciences, such as developmental biology, biochemistry, human genetics, and cell and tumor biology.

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Editore
Plenum Pub Corp
Data di pubblicazione
1980
Lingua
Inglese
ISBN 10 
0306404087
ISBN 13 
9780306404085
Rilegatura
Copertina rigida
Numero di pagine
446
Contatto del produttore
non disponibile
Persona responsabile
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Germania

Altre edizioni note dello stesso titolo

9781461575078: Monoclonal Antibodies: Hybridomas: A New Dimension in Biological Analyses

Edizione in evidenza

ISBN 10:  1461575079 ISBN 13:  9781461575078
Casa editrice: Springer, 2012
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