Genetic Engineering: Principles and Methods: 23 - Rilegato

 
9780306466458: Genetic Engineering: Principles and Methods: 23
Rilegato
ISBN 10: 0306466457 ISBN 13: 9780306466458
Casa editrice: Springer-Verlag GmbH, 2001

Sinossi

Over the past decade, our laboratory and others have been concerned with molecular archaeological studies aimed at revealing the origins and evolutionary histories of permeases (1). These studies have revealed that several different families, defined on the basis of sequence similarities, arose independently of each other, at different times in evolutionary history, following different routes. When complete microbial genomes first became available for analysis, we adapted p- existing software and designed new programs that allowed us quickly to identify probable transmembrane proteins, estimate their topologies and determine the likelihood that they function in transport (2). This work allowed us to expand previously-recognized families and to identify dozens of new families. All of this work then led us to attempt to design a rational but comprehensive classification system that would be applicable to the complete complement of transport systems found in all living organisms (3). The classification system that we have devised is based primarily on mode of transport and energy coupling mechanism, secondarily on molecular phylogeny, and lastly on the substrate specificities of the individual permeases (4).

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Informazioni sull?autore

Jane K. Setlow, PhD. has championed the field of genetics for over 30 years, agreeing to edit Genetic Engineering: Principles & Methods since its inception in 1979. An internationally recognized scientist with numerous publications, Dr. Setlow is the former Chairperson of the NIH Recombinant DNA Molecule Advisory Committee (RAC). Her lab can found at Brookhaven National Laboratory, Upton, New York.

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Editore
Springer-Verlag GmbH
Data di pubblicazione
2001
Lingua
Inglese
ISBN 10 
0306466457
ISBN 13 
9780306466458
Rilegatura
Copertina rigida
Numero di pagine
256
Redattore
Setlow Jane K.
Contatto del produttore
non disponibile
Persona responsabile
ProductSafety@springernature.com
ProductSafety@springernature.com

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Altre edizioni note dello stesso titolo

9781475787986: Genetic Engineering: Principles and Methods: 23

Edizione in evidenza

ISBN 10:  1475787987 ISBN 13:  9781475787986
Casa editrice: Springer, 2013
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