Principles of Medical Biochemistry: With STUDENT CONSULT Online Access - Brossura

Meisenberg, Gerhard; Simmons, H. William, Ph.d.; Simmons, William H.

Brossura

ISBN 10: 0323029426 ISBN 13: 9780323029421

Casa editrice: Mosby Inc, 2006

Riassunto

The smart way to study!
Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.

• Half the size and weight of the usual biochemistry text.
• Includes clinical cases throughout the text, and a case study section at the end in order to illustrate the practical application of biochemistry concepts.
• Comprehensive coverage of all the topics that are typically included in medical biochemistry courses
• Focuses on topics that are of specific medical interest, such as plasma proteins and lipoproteins, molecular carcinogenesis, laboratory diagnostic tests, and the rapidly evolving new applications of molecular genetics.

• Expanded coverage of molecular genetics, genome structure, and the molecular basis of genetic disease.
• Discussions of gene therapy and germline gene modifications.
• Information on molecular carcinogenesis, apoptosis, and signaling pathways.
• Superb new page design with full color illustrations
• Online version via the STUDENT CONSULT website with USMLE test questions and integration links

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Contenuti

Table of Contents

Part One: Principles of Molecular Structure and Function.

Chapter 1: Introduction to Biomolecules.

WATER: THE SOLVENT OF LIFE.
COVALENT BONDS AND NONCOVALENT INTERACTIONS
THE MAJOR CLASSES OF BIOMOLECULES.

Chapter 2: Protein structure.

THE AMINO ACIDS.
LEVELS OF PROTEIN STRUCTURE
THE PHYSICAL PROPERTIES OF PROTEINS

Chapter 3: Oxygen Transporters: Hemoglobin and Myoglobin.

Chapter 4: Enzymatic Reactions.

THERMODYNAMICS
ENZYME KINETICS
ENZYME INHIBITION
REACTION TYPES AND REACTION MECHANISMS

Chapter 5: Coenzymes

Part Two: Cell and Tissue Structure.
Chapter 6: Biological Membranes.

THE LIPID BILAYER.
MEMBRANE PROTEINS.
MEMBRANE TRANSPORT.
Chapter 7: The Cytoskeleton

Chapter 8: The Extracellular Matrix.
FIBROUS PROTEINS OF THE EXTRACELLULAR MATRIX.
THE AMORPHOUS GROUND SUBSTANCE

Part Three: Genetic Information: DNA, RNA, and Protein Synthesis.
Chapter 9: DNA, RNA, and Protein Synthesis: The Central Dogma of Molecular Biology.
DNA STRUCTURE AND DNA REPLICATION.
RNA AND THE GENETIC CODE.
PROTEIN SYNTHESIS.
REGULATION OF GENE EXPRESSION.

Chapter 10: Viruses

Chapter 11: The Human Genome and Its Expression.
CHROMATIN STRUCTURE.
THE ARCHITECTURE OF THE HUMAN GENOME.
TRANSCRIPTION AND TRANSLATION.
Chapter 12: The processing and targeting of proteins.
Chapter 13: Introduction to Genetic Diseases.

MUTATIONS AND DNA REPAIR.
THE HEMOGLOBINOPATHIES.

Chapter 14: DNA Technology.

THE TOOLS.
THE DIAGNOSIS OF GENETIC DISORDERS.
CLONING IN MICROORGANISMS.
GENE THERAPY.

Part Four: Signaling and signaling cascades.

Chapter 15: The Blood.

THE COMPONENTS OF PLASMA
PLASMA PROTEINS.
THE IMMUNOGLOBULINS.
THE BLOOD CLOTTING SYSTEM.
CLINICAL LABORATORY DIAGNOSIS.

Chapter 16: Extracellular Messengers.

THE STEROID HORMONES.
THE THYROID HORMONES.
THE BIOGENIC AMINES
PEPTIDES AND PROTEINS
THE EICOSANOIDS
NEUROTRANSMITTERS.
Chapter 17: Intracellular Messengers.

RECEPTORS.
G PROTEINS, SECOND MESSENGERS, AND PROTEIN KINASES.
RECEPTORS WITH ENZYMATIC ACTIVITIES.

Chapter 18: Cellular Growth Control and Cancer.
CELL CYCLE CONTROL.
MITOGENIC SIGNALING.
SOMATIC MUTATIONS AND CANCER.
SPECIFIC CANCERS.

Part Five: Metabolism.

Chapter 19: Digestive Enzymes.

Chapter 20: Introduction to Metabolism.

Chapter 21: The Oxidation of Glucose: Glycolysis, the TCA Cycle, and Oxidative Phosphorylation.

GLYCOLYSIS: FROM GLUCOSE TO PYRUVATE.
PYRUVATE DEHYDROGENASE AND THE TCA CYCLE: FROM PYRUVATE TO CARBON DIOXIDE AND REDUCED COENZYMES.
THE RESPIRATORY CHAIN AND OXIDATIVE PHOSPHORYLATION.
INHIBITION OF OXIDATIVE METABOLISM

Chapter 22: Carbohydrate Metabolism.

GLUCONEOGENEIS.
GLYCOGEN METABOLISM.
THE METABOLISM OF FRUCTOSE AND GALACTOSE.
THE MINOR PATHWAYS OF CARBOHYDRATE METABOLISM.

Chapter 23: The Metabolism of Fatty Acids and Triglycerides.

THE GENERATION OF METABOLIC ENERGY FROM FATTY ACIDS.
FROM CARBOHYDRATE TO FAT.

Chapter 24: The Metabolism of Membrane Lipids.

THE METABOLISM OF PHOSPHOGLYCERIDES AND SPHINGOLIPIDS.
CHOLESTEROL METABOLISM.

Chapter 25: Lipid Transport.

THE HIGHWAYS OF LIPID TRANSPORT.
LIPOPROTEINS AND ATHEROSCLEROSIS.
Chapter 26: Amino Acid Metabolism.
THE FATE OF THE AMINO NITROGEN.
AMINO ACID DEGRADATION.

Chapter 27: Heme Metabolism.

Chapter 28: The Metabolism of Purines and Pyrimidines.

Chapter 29: Vitamins and Minerals.

THE WATER-SOLUBLE VITAMINS.
THE FAT-SOLUBLE VITAMINS.
THE TRACE MINERALS.

Chapter 30: Integration of Metabolism.

HORMONAL REGULATION.
FEEDING AND FASTING
DIABETES MELLITUS.
PHYSICAL EXERCISE.
THE METABOLISM OF XENOBIOTICS.

Product Description

Book by Gerhard Meisenberg William H Simmons

Dettagli dell'edizione

• Editore: Mosby Inc
• Data di pubblicazione: 2006
• Lingua: Inglese
• ISBN 10: 0323029426
• ISBN 13: 9780323029421
• Rilegatura: Copertina flessibile
• Numero edizione: 2
• Numero di pagine: 678
• Contatto del produttore: non disponibile
• Persona responsabile: LSWR Group; b.criscuolo@lswr.it; ; Via Spadolini, 7; Milano; Italia