Comprehensive Chirality - Rilegato

Rilegato

ISBN 10: 0323906443 ISBN 13: 9780323906449

Casa editrice: Academic Pr, 2024

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Comprehensive Chirality, Second Edition, Nine Volume Set provides a complete overview of the field, including chiral research relevant to synthesis, analytic chemistry, catalysis, and pharmaceuticals. This new edition is focused on reactions and methods, and less so on abstract concepts discussed in the first edition. Some of the original volumes were combined to make room for newer areas, new volumes introduced, and other volumes updated. Whether in an Academic or Corporate setting, these chapters will form an invaluable resource for advanced students/researchers new to an area and those who need further background or answers to a particular problem, particularly in the development of drugs.

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Informazioni sull'autore

Janine Cossy

Molecular, Macromolecular Chemistry and Materials (C3M)

ESPCI Paris, PSL University, CNRS, 75005 Paris, France

Professor Janine Cossy graduated from the University of Reims (France) working under the supervision of Prof. Jean-Pierre P�te. After a postdoctoral stay with Prof. Barry Trost (1980-1982) at the University of Wisconsin (USA), she returned to Reims where she became Director of Research CNRS in 1990. The same year, she moved to Paris to become Professor of Organic Chemistry at the Ecole Sup�rieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris). She has published more than 560 articles and filed 18 patents in the field of synthetic organic chemistry and natural product synthesis. She was Associate Editor at Organic Letters from 2005 to 2018 and since October 2023, she is Tetrahedron Associate Editor. Her research efforts have resulted in more than 560 publications and 18 patents. Among the awards, she received: the CNRS Silver Medal (France, 1996); the UK Royal Society Rosalyn Franklin International Lecturership awarded to internationally recognized women scientists (UK, 2005); the E. C. Taylor Senior Award (2015); the IUPAC 2019 Distinguished Women in Chemistry or Chemical Engineering (2019). She was elected at the French Academy of sciences in 2017 and in 2022, she has been elected at the national Academy of Pharmacy. In addition, she was nominated Chevalier de l’Ordre National du M�rite and promoted to Officier in 2018. In 2013, she was nominated Chevalier de la L�gion d’Honneur and was promoted to Officier in 2023. She is the co-funder of two companies: CDP-Innovation and Acanthe Biotech.

Affiliations

Molecular, Macromolecular Chemistry and Materials (C3M)

ESPCI Paris, PSL University, CNRS, 75005 Paris, France

Expertise

Development of synthetic methods: Enantioselective reactions, rearrangements, radicals, photochemistry, organometallic reactions, biocatalysis, plasma reactions. Synthesis of natural products and/or bioactive compounds.

Dalla quarta di copertina

Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals.

Key highlights include:
- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.
- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.
- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.
- Asymmetric Photochemistry: light-induced asymmetric transformations.
- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.
- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.
- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.
- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers.

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