Basic Clinical Radiobiology, 3Ed - Rilegato

Gordon Steel, G

Rilegato

ISBN 10: 0340807830 ISBN 13: 9780340807835

Casa editrice: CRC Press, 2002

Riassunto

This concise, but comprehensive textbook sets out all the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology. The fully updated 3rd edition continues to discuss the basis of radiation therapy and presents the principles and significant scientific developments that underlie current attempts to improve the radiotherapeutic managemnet of all cancers.



New topics in the 3rd edition include chapters on volume effects in normal tissues and the L-Q approach in clinical practice, with major revisions to sections on cell proliferation, radiation cytogenetics, radiotherapy-related morbidity, hyperfractionation and individualisation of radiotherapy. The book continues to provide invaluable advice for trainee and practising radiation oncologists from a team of internationally respected contributors and draws on the considerable experience of the Editor, gained during his time as Course Director of the annual ESTRO course in Basic Clinical Radiobiology.

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Contenuti

Introduction: the significance of radiobiology for radiotherapy
Cell proliferation and growth rate tumours
Proliferative and cellular organization of normal tissues
Radiation response and tolerance of normal tissues
Volume effects in normal tissues
Clonogenic cells and the concept of cell survival
Models of radiation cell killing
DNA damage and cell killing
Genetic control of the cellular response to ionizing radiation
Dose-response relationships in radiotherapy
Radiotherapy-related morbidity
Time-dose relationships: the L-Q approach
The L-Q approach in clinical practice
Hyperfractionation and accelerated radiotherapy
The oxygen effect
Modifying the tumour microenvironment
The radiobiology of tumours
The dose-rate effect: brachytherapy and targeted radiotherapy
Particle beams in radiotherapy
Combination of radiotherapy and chemotherapy
Re-treatment tolerance of normal tissues
Individualization of radiotherapy.

Product Description

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Dettagli dell'edizione

• Editore: CRC Press
• Data di pubblicazione: 2002
• Lingua: Inglese
• ISBN 10: 0340807830
• ISBN 13: 9780340807835
• Rilegatura: Copertina rigida
• Numero edizione: 3
• Numero di pagine: 280
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile