Microarray Innovations: Technology and Experimentation - Brossura

 
9780367385811: Microarray Innovations: Technology and Experimentation
Brossura
ISBN 10: 0367385813 ISBN 13: 9780367385811
Casa editrice: CRC Press, 2019

Sinossi

In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarray Innovations: Technology and Experimentation examines the incredibly powerful nature of array technology and the ways in which it can be applied to understanding the genomic basis of disease.

Explores a myriad of applications in use today

This volume explores recent innovations in the microarray field and tracks the evolution of the major platforms currently used. The international panel of contributors presents a survey of the past five years’ research and advancements in microarray methods and applications and their usage in drug discovery and biomedical research. The contributions discuss improvements in automation (array fabrication and hybridization), new substrates for printing arrays, platform comparisons and contrasts, experimental design, and data normalization and mining schemes. They also review epigenomic array studies, electronic microarrays, comparative genomic hybridization, microRNA arrays, and mutational analyzes. In addition, the book provides coverage of important clinical diagnostic arrays, protein arrays, and neuroscience applications.

Examines improved methodologies

As microarrays have evolved steadily over time from archetypical in-house complementary DNA (cDNA) arrays to robust commercial oligonucleotide platforms, there has been a migration to higher density biochips with increasing content and better analytical methodologies. This compendium summarizes the vast advances that have been made in this technology, highlighting the supreme advantages of microarray-based appro

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Informazioni sull?autore

Gary Hardiman

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
CRC Press
Data di pubblicazione
2019
Lingua
Inglese
ISBN 10 
0367385813
ISBN 13 
9780367385811
Rilegatura
Copertina flessibile
Numero edizione
1
Numero di pagine
360
Redattore
Hardiman Gary
Contatto del produttore
non disponibile
Persona responsabile
non disponibile

Altre edizioni note dello stesso titolo

9781420094480: Microarray Innovations: Technology and Experimentation

Edizione in evidenza

ISBN 10:  1420094483 ISBN 13:  9781420094480
Casa editrice: CRC Press, 2009
Rilegato