Receptor - Based Drug Design - Brossura

 
9780367400521: Receptor - Based Drug Design
Brossura
ISBN 10: 0367400529 ISBN 13: 9780367400521
Casa editrice: CRC Press, 2019

Sinossi

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design.
Explains the experimental and theoretical methods used to characterize interactions between ligands and receptors-providing the pharmacological information needed to solve treatment problems and facilitate the drug design process!
Demonstrating the achievements of the receptor-based approach in therapeutics and indicating future directions, Receptor-Based Drug Design

  • introduces novel computer-assisted strategies for the design of new agonists, antagonists, and inverse agonists for G-protein-coupled receptors
  • shows how to assess agonist concentration-effect curve data
  • discusses radioligand binding assays
  • presents new in vitro multiarray assays for G-protein-coupled receptors
  • explains the use of individual second messenger signaling responses in analyzing drug-receptor interactions
  • examines the role of electrophysiology in finding new drugs and drug targets
  • describes selectively acting b-adrenoceptor agonists and glucocorticoid steroids for asthma treatment
  • outlines the rationale for using angiotensin receptor antagonists
  • and more!
    Written by over 25 international authorities and containing nearly 1200 bibliographic citations, Receptor-Based Drug Design is a practical resource for pharmacologists, pharmacists, and pharmaceutical scientists; organic and medicinal chemists and biochemists; molecular biologists; biomedical researchers; and upper-level undergraduate and graduate students in these disciplines.

    • Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

    Informazioni sull?autore

    Leff Paul

    Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

    Editore
    CRC Press
    Data di pubblicazione
    2019
    Lingua
    Inglese
    ISBN 10 
    0367400529
    ISBN 13 
    9780367400521
    Rilegatura
    Copertina flessibile
    Numero edizione
    1
    Numero di pagine
    400
    Redattore
    Leff Paul
    Contatto del produttore
    Taylor and Francis, GPSR Taylor and Francis
    gpsr@taylorandfrancis.com

    Taylor & Francis Verlag GmbH, Kaufingerstraße 24
    München
    80331
    Germania

    Altre edizioni note dello stesso titolo

    9781420001136: Receptor - Based Drug Design

    Edizione in evidenza

    ISBN 10:  1420001132 ISBN 13:  9781420001136
    Rilegato