Articoli correlati a Mechanisms of Lymphocyte Activation and Immune Regulation...
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In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.
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Contenuti
Regulation and Function of the E2A Proteins in B Cell Development.- Multiple Roles for Blimp-1 in B and T Lymphocytes.- Memory B Cell Evolution: B Cell Biology.- BCR-linked Factors in Developmental Fate Decisions.- Gene Regulatory Networks that Orchestrate the Development of B Lymphocyte Precursors.- Rules for the Rearrangement Events at the L Chain Gene Loci of the Mouse.- Regulation of AID Function In Vivo.- Targeting of AID to Immunoglobulin Genes.- Targeting AID to the Ig Genes.- DNA Replication to Aid Somatic Hypermutation.- Regulation of Activation Induced Deaminase via Phosphorylation.- Modulation of MHC Class II Signal Transduction by CD19.- Role of NFUP?B Signaling in Normal and Malignant B Cell Development.- Fc Receptor–like Proteins (FCRL): Immunomodulators of B Cell Function.- Tolerance Mechanisms in the Late Phase of the Antibody Response.- Role of RS/?DE in B Cell Receptor Editing.- The Regulation of Receptor Editing.- B Cell Hyporesponsiveness and Autoimmunity: A New Paradigm.
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Mechanisms of Lymphovyte Activation and Immune Regulation XI. B Cell Biology.
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New York, Springer., 2007
ISBN 10: 0387465278
ISBN 13: 9780387465272
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X, 196 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Advances in Experimental Medicine and Biology, Vol. 596. Sprache: Englisch. Codice articolo 31462AB
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Mechanisms of Lymphocyte Activation and Immune Regulation XI
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Mechanisms Of Lymphocyte Activation And Immune Regulation Xi: B Cell Biology
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Mechanisms Of Lymphocyte Activation And Immune Regulation Xi: B Cell Biology
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Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide. Codice articolo ABNR-88227
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Mechanisms of Lymphocyte Activation and Immune Regulation XI
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Mechanisms of Lymphocyte Activation and Immune Regulation XI
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Mechanisms of Lymphocyte Activation and Immune Regulation XI
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Discusses the latest developments in the area of lymphocyte activation and immune regulationIn recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the gener. Codice articolo 5910368
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Mechanisms of Lymphocyte Activation and Immune Regulation XI
Editore:
Springer US, Springer New York Feb 2007, 2007
ISBN 10: 0387465278
ISBN 13: 9780387465272
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role and mechanism of DNA repair proteins in somatic hypermutation has been elucidated. Genetic mutation studies have been instrumental in providing insight into some of the mechanisms involved in targeting CSR to various switch DNA regions located upstream of C region genes, especially a role of AID motifs, transcription, and R-loops. Recent studies support a dominant role of receptor editing in central B cell tolerance and signaling pathways that regulate receptor editing in self-reactive and non-self-reactive immature B cells. These were some of the topics of discussion at the 11th International Conference on B cell Biology. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity. 208 pp. Englisch. Codice articolo 9780387465272
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Mechanisms of Lymphocyte Activation and Immune Regulation XI: B Cell Biology (Advances in Experimental Medicine and Biology, 596)
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Mechanisms of Lymphocyte Activation and Immune Regulation XI
Editore:
Springer US, Springer New York Feb 2007, 2007
ISBN 10: 0387465278
ISBN 13: 9780387465272
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
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Buch. Condizione: Neu. Neuware -In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role and mechanism of DNA repair proteins in somatic hypermutation has been elucidated. Genetic mutation studies have been instrumental in providing insight into some of the mechanisms involved in targeting CSR to various switch DNA regions located upstream of C region genes, especially a role of AID motifs, transcription, and R-loops. Recent studies support a dominant role of receptor editing in central B cell tolerance and signaling pathways that regulate receptor editing in self-reactive and non-self-reactive immature B cells. These were some of the topics of discussion at the 11th International Conference on B cell Biology. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch. Codice articolo 9780387465272
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