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Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cellsand not the major bulk of the tissuethat are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy.
The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.
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Cancer is a major cause of human morbidity and mortality worldwide. Despite decades of basic and clinical research, the outcome for many cancer patients is still dismal. Although the existence of "stem-like" cells in cancer was hypothesized more than 150 years ago, recent discoveries have the potential to revolutionize cancer therapy. In particular, we now know that many cancers contain a fraction of self-renewing, drug- and radiation-resistant cells (cancer stem cells or cancer-initiating cells) and it is these cellsand not the major bulk of the tissuethat are the root cause for cancer initiation, relapse and metastasis. In a single volume, Stem Cells and Cancer offers up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies across all major types of cancer. It provides timely, cutting-edge information about cancer stem cells from the perspectives of both the basic and clinical sciences.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Stem Cells and Cancer
Da: Buchpark, Trebbin, Germania
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Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 312 | Sprache: Englisch | Produktart: Bücher. Codice articolo 4945873/12
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Stem Cells and Cancer
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Springer, 2009
ISBN 10: 0387896104
ISBN 13: 9780387896106
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Stem Cells and Cancer
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Will provide timely, cutting-edge information about cancer stem cells from the perspectives of both the basic and clinical sciencesWill provide timely, cutting-edge information about cancer stem cells from the perspectives of both the basic and clini. Codice articolo 5911545
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Stem Cells and Cancer
Print on DemandDa: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells-and not the major bulk of the tissue-that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy.The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies. 312 pp. Englisch. Codice articolo 9780387896106
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Stem Cells and Cancer
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Springer New York, Springer US Jun 2009, 2009
ISBN 10: 0387896104
ISBN 13: 9780387896106
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Buch. Condizione: Neu. Neuware -Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells¿and not the major bulk of the tissue¿that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy.The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch. Codice articolo 9780387896106
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Stem Cells and Cancer
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Springer New York, Springer US, 2009
ISBN 10: 0387896104
ISBN 13: 9780387896106
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells-and not the major bulk of the tissue-that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy.The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies. Codice articolo 9780387896106
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Stem Cells and Cancer
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Hardcover. Condizione: Like New. Like New. book. Codice articolo ERICA75403878961045
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