The papers in this volume represent the proceedings of the XIIth North American Testis Workshop held in Tampa, Florida, April 1993 and put forth recent developments in the study of endocrine and gametogenic functions of the male gonad.
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1. Endangered Species Spermatozoa: Diversity, Research, and Conservation.- I. Functional Significance of Morphological Relationships.- 2. Stage-Related Functions of Sertoli Cells: Lessons from Lower Vertebrates.- 3. Structure-Function Relationships in Somatic Cells of the Testis and Accessory Reproductive Glands.- 4. Local Growth Factor Effects During Spermatogenesis.- 5. Stage-Specific Expression of the Cathepsin L Gene by Rat Sertoli Cells.- II. Functions of Somatic Cells in the Testis.- 6. Characterization, Regulation, and Tissue-Specific Expression of Steroidogenic Enzymes.- 7. Molecular Genetics, Structure-Function Relationships, and Tissue-Specific Expression and Regulation of the 3?HSD Gene Family.- 8. Regulation of DNA Synthesis in Leydig Cells.- 9. Use of Two-Compartment Cultures of Sertoli Cells for Investigating Blood-Testis Barrier Physiology.- 10. Mediation of the Hormonal Stimulation of Steroidogenesis by the Polypeptide Diazepam Binding Inhibitor.- 11. Inhibition of Spermatogenesis by Tetanus Toxin Expression in Sertoli Cells of Transgenic Mice.- III. Signaling Molecules and Their Receptors.- 12. Pituitary Control of Fetal and Adult Leydig Cells and Physiological Regulation of Gonadotropin Gene Expression and Secretion in the Male.- 13. Expression of the FSH Receptor in the Sertoli Cells.- 14. Regulation of Germ Cell Proliferation In Vitro by Activins, Follistatin, and Other Growth Factors.- 15. Androgen Action in Sertoli and Peritubular Cells.- 16. Hormonal Control of Apoptotic Cell Death in the Testis.- 17. Involvement of Liver-Regulating Protein-Like Molecule in Sertoli-Germ Cell Cross Talk.- 18. 5?-Reductase Activity Increased by Oxytocin in the Rat Testis.- 19. Induction by LH/hCG of an Increase in the Rate of Pig Leydig Cell Receptor mRNA Degradation.- 20. Genetics and Luteinizing Hormone Receptors.- IV. Regulation of Germ Cells, Differentiation, and Gene Expression.- 21. Development of Postnatal Gonocytes In Vivo and In Vitro.- 22. Role of Retinoids in Spermatogonial Proliferation and Differentiation and the Meiotic Prophase.- 23. Role and Regulation of Spermatogenic Cell-Specific Gene Expression: Enzymes of Glycolysis.- 24. Regulation of the Cyclic Nucleotide-Dependent Pathway in Seminiferous Tubule Cells.- 25. Testis-Specific Proprotein Convertase 4: Gene Structure, Optional Exons, and mRNA Isoforms.- 26. Neonatal Propylthiouracil Treatment as a Model System for Studying Factors Controlling Testis Growth and Sperm Production.- V. Recent Developments in the Studies of Male Reproductive Functions.- 27. Molecular Biology of Human Androgen Insensitivity Syndrome.- 28. Congenital Absence of the Vas Deferens and the Cystic Fibrosis Transmembrane Conductance Regulator Gene: Evidence for a Common Genetic Background.- 29. GnRH Neurons in an Interpretation of Kallmann’s Syndrome.- Author Index.
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