A review of current research discoveries shedding light on the function of c-Myc in neoplasia and overviewing the most current understandings of signal tranduction and neoplastic transformation. The discussions present the discovery of "myc" starting with the recognition of retroviral "myc" and the cloning of the vertebrate homologs, regulation of c-Myc gene expression and protein products, observations on c-Myc protein structure and function, and the genes that appear to be regulated by c-Myc and their role in induced neoplastic transformation and apoptosis. Originally published by R.G. Landes, but now handled by Chapman & Hall. To confuse matters, two additional ISBNs are associated with the book: 1-57059-312-4, and 3-640-60623-7. Annotation c. by Book News, Inc., Portland, Or.
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