Multiple Sclerosis, 2Ed - Rilegato

Rilegato

ISBN 10: 0412308908 ISBN 13: 9780412308901

Casa editrice: CRC Press, 1998

Riassunto

Multiple sclerosis is a serious condition to the patient and their family, an awesome task to the clinician who confronts it, and a formidable challenge to the investigator who chooses to research it. With evidence implicating an immunologic basis for lesion pathogenesis and the myelin sheath as the primary target, there has been in recent years, a heavy bias towards a break in self-tolerance and autoimmunity as major mechanisms. This and other immunologic anomalies now figure prominently in several treatment modalities and are presented in a balanced fashion in many of the accompanying chapters.



The editors labored long over the composition of the table of contents and contributors. Accordingly, they decided to meld the works of clinicians from several disciplines with laboratory-based scientists actively researching neuroimaging, electrophysiology, molecular neuropathology, neurobiology, immunopathogenesis and virology. To accomplish this, the book is divided into four sections: clinical parameters, neuropathology and etiopathogenesis, primary treatments, and symptomatic treatment based on advances in psychiatry, medicine and surgery. Cumulatively, these are areas that have helped to accomplish the goal of full longevity and modestly improved quality of life. In an attempt to keep abreast with developments in the field and to counter the possibility of becoming prematurely outdated, each chapter not only provides didactic coverage but also indicates recent trends and makes prediction for the future. Some sections are even more speculative and provide rationale for therapies not yet in vogue. The net result is a fresh, kaleidscopic overview of multiple sclerosis from both the applied and basic standpoints - the balance between broad brush strokes and fine details has been carefully weighed.

Su questo libro

Recensione

...excellent...I recommend it to anyone who wishes to learn about the disease
British Medical Journal

Contenuti

Clinical Parameters
Clinical features of multiple sclerosis
Optic neuritis
Imaging in multiple sclerosis
Evoked potentials in multiple sclerosis
Evoked potentials in multiple sclerosis
Multiple sclerosis: cerebrospinal fluid
Natural history of multiple sclerosis
Risk factors in multiple sclerosis
Neuropathology and etiopathogenesis
The neuropathology of multiple sclerosis
The immunocytochemistry of multiple sclerosis plaques
Genes and development of myelin-forming cells
Pathophysiology of the demyelinated nerve fiber
Genetic influences in multiple sclerosis
Immnunology of multiple sclerosis
Immunology of multiple sclerosis
The lesion in multiple sclerosis and chronic relapsing experimental allergic encephalomyelites: a structural comparison
The proposed viral etiology of multiple sclerosis
Treatment: etiopathogenetic
Current disease-modifying therapies in multiple sclerosis
An investigational approach to disease therapy in multiple sclerosis
Conduct of a clinical trial in multiple sclerosis.
Treatment: symptomatic.Neuropsychological aspects of multiple sclerosis
The bladder in multiple sclerosis
Sexual dysfunction in the patient with multiple sclerosis
Comprehensive management of multiple sclerosis
Index

Dettagli dell'edizione

• Editore: CRC Press
• Data di pubblicazione: 1998
• Lingua: Inglese
• ISBN 10: 0412308908
• ISBN 13: 9780412308901
• Rilegatura: Copertina rigida
• Numero edizione: 2
• Numero di pagine: 448
• Redattore: Raine Cedric S., McFarland Henry F. M.D., Tourtellotte Wallace W.
• Contatto del produttore: non disponibile
• Persona responsabile: Buchpark GmbH; gpsr@buchpark.de; ; Krügerweg 1; Trebbin; Brandenburg; 14959; Germania