The structure of the nucleic acids; genomes of eukaryotes, bacteria and viruses - chromosome organization; degradation and modification of nucleic acids; the metabolism of nucleotides; replication of DNA; DNA damage, repair and recombination; the arrangement of genes; RNA biosynthesis; control of transcription; processing of RNA transcripts and its control; the translation of mRNA - protein synthesis. Appendices: occurrence and chemical analysis; isolation and separation of nucleic acids; hybridization of nucleic acids; methods of labelling nucleic acids; determination of nucleic acid sequences; cloning DNA; analysis and manipulation of cloned DNA.
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`With its emphasis on the biochemistry that has led to so much of our knowledge of nucleic acids, this text is a valuable complement to other works that concentrate on the contribution made by more genetic approaches.'
Nature
`This book is very readable with helpful diagrmas, and an extensive bibliography at the end of each chapter; thus it is useful not only for third year undergraduate courses, but also as a basic reference book.'
New Scientist
`The authors have contiued to select their material to fulfil the requirements of advanced undergraduate, and graduate, students in biochemistry, genetics and molecular biology ... The book is very readable and profusely illustrated, and embraces most of the current trends in molecular biology.'
Febs Letters
Preface. Introduction. The structure of the nucleic acids. Genomes of eukaryotes, bacteria and viruses: chromosome organization. Degradation and modification of nucleic acids. The metabolism of nucleotides. Replication of DNA. Repair, recombination and rearrangement of DNA. The arrangement of genes, RNA biosynthesis. Control of transcription. Processing of RNA transcripts and its control. The translation of mRNA: protein synthesis. Appendix.
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Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. When the first edition of this book was published in 1950, it predated the publication of the double-helical structure of DNA by three years. It is not, therefore, surprizing that nothing of the original book remains in the current edition. Indeed, such is . Codice articolo 5914599
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