This classic textbook now enters its forth edition, offering a distillation of decades of research and teaching experience in toxicology. Known all over the world after its translation into six languages, Lu's Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment is a benchmark text that brings clarity and insight into a rapidly evolving subject. Noted for its concise yet broad coverage of the subject, this new edition includes new chapters on over-the counter preparations, lactation and occupational toxicology. In addition, it covers: " The action of chemicals that cause cancer, mutations, congenital malformations and organ or system specific effects " Why chemical target specific organs and systems and how these effects are revealed by laboratory tests " The host and environmental factors that modify these effects " The effects of food additives, pesticides, metals, pollutants in air, water and soil, as well as toxicants encountered in workplaces " The procedures commonly used in assessing risk associated with these chemicals The breadth of this book makes it ideal for students requiring an introduction to toxicology, whether those specializing in toxicology or those from other biomedical disciplines who need a clear and concise overview of the field. The inclusion of separate subject and chemical indexes also makes it a useful shelf reference for more experienced researchers. In Lu's Basic Toxicology, Frank Lu and Sam Kacew have transcribed their vast experience to produce a book which will be an invaluable reference to student and practising toxicologists everywhere.
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GENERAL PRINCIPLES OF TOXICOLOGY
General Considerations
Absorption, Distribution, and Excretion of Toxicants
Biotransformation of Toxicants
Toxic Effects
Modifying Factors of Toxic Effects
TESTING PROCEDURES FOR CONVENTIONAL AND NON-TARGET ORGAN TOXICITIES
Conventional Toxicity Studies
Carciogenesis
Mutagenesis
Developmental Toxicology
Lactation
TARGET ORGANS AND SYSTEMS
Toxicology of the Immune System
Respiratory System: Inhalation Toxicology
Toxicology of the Liver
Toxicology of the Kidney
Toxicology of the Skin
Toxicology of the Eye
Toxcicology of the Nervous System
Reproductive and Cardiovascular Systems
TOXIC SUBSTANCES AND RISK ASSESSMENT
Food Additives and Contaminants
Toxicity of Pesticides
Toxicity of Metals
Over-the-Counter Preparations
Environmental Pollutants
Occupational Toxicology
Toxicologic Evaluation: Assessment of Safety/Risk
Book by Lu Frank C Kacew Sam
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